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Information on EC 3.4.21.53 - Endopeptidase La

for references in articles please use BRENDA:EC3.4.21.53

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IUBMB Comments

Product of the lon gene in Escherichia coli. ATP hydrolysis is linked with peptide bond hydrolysis; vanadate inhibits both reactions. Type example of peptidase family S16. A similar enzyme occurs in animal mitochondria

The enzyme appears in viruses and cellular organisms
Reaction Schemes
hydrolysis of proteins in presence of ATP

Synonyms
protease, serine protease, clpxp, lon protease, lonp1, protease la, atp-dependent lon protease, protease lon, aaa+ protease, ms-lon, more