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Information on EC 7.1.1.2 - NADH:ubiquinone reductase (H+-translocating)

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IUBMB Comments
The enzyme is a very large complex that participates in electron transfer chains of mitochondria and aerobic bacteria, transferring electrons from NADH to the ubiquinone pool. Reversed electron transport through this enzyme can reduce NAD+ to NADH.
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The enzyme appears in viruses and cellular organisms
Synonyms
complex i, complex 1, nadh dehydrogenase, mitochondrial complex i, grim-19, respiratory complex i, respiratory chain complex i, nadh:ubiquinone oxidoreductase, mitochondrial nadh dehydrogenase, ndh-1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + ubiquinone + 6 H+[side 1] = NAD+ + ubiquinol + 7 H+[side 2]
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