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Information on EC 7.1.1.2 - NADH:ubiquinone reductase (H+-translocating)

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IUBMB Comments
A flavoprotein (FMN) containing iron-sulfur clusters. The complex is present in mitochondria and aerobic bacteria. Breakdown of the complex can release EC 1.6.99.3, NADH dehydrogenase. In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD+ to NADH.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
107364096, 13 kDa differentiation-associated protein, AIF-homologous mitochondrion-associated inducer of death, AIFM1, AIFM2, alternative complex I, alternative NADH oxidoreductase, alternative NADH: ubiquinone oxidoreductase, alternative NADH:ubiquinone oxidoreductase, AMAPOR, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + ubiquinone + 6 H+[side 1] = NAD+ + ubiquinol + 7 H+[side 2]
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PATHWAY SOURCE
PATHWAYS
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