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Literature summary for 2.7.11.30 extracted from

  • Li, W.; Tang, Q.; Dai, N.; Feng, W.; Xie, C.; Cheng, G.; Liu, X.; Zhang, W.; Hu, X.; Gu, C.
    Receptor-interacting serine/threonine kinase 1- and 3-dependent inflammation induced in lungs of chicken infected with Pasteurella multocida (2020), Sci. Rep., 10, 6340 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [receptor-protein] Gallus gallus
-
 ADP + [receptor-protein] phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Gallus gallus
-
macrophage
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [receptor-protein]
-
 Gallus gallus ADP + [receptor-protein] phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 56000, isoform RIPK3, SDS-PAGE Gallus gallus
? x * 76000, isoform RIPK1, SDS-PAGE Gallus gallus

Synonyms

Synonyms Comment Organism
receptor-interacting serine/threonine kinase 1 isoform Gallus gallus
receptor-interacting serine/threonine kinase 3 isoform Gallus gallus
rIPK1 isoform Gallus gallus
RIPK3 isoform Gallus gallus

Expression

Organism Comment Expression
Gallus gallus apoptosis activates isoforms RIPK1 and RIPK3 up

General Information

General Information Comment Organism
physiological function isoforms RIPK1 and RIPK3 are involved in the injury process of chicken lungs after infection with Pasteurella multocida. The proinflammatory response involving isoforms RIPK1 and RIPK3 suggests histopathological changes associated with heterophilic granulocytes that are associated with host response to Pasteurella multocida infection in the lung Gallus gallus