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Synonyms
prors, prolyl-trna synthetase, glutamyl-prolyl-trna synthetase, glutamyl-prolyl trna synthetase, gluprors, prolyl trna synthetase, prorstt, procysrs, bifunctional aminoacyl-trna synthetase, glutamyl-/prolyl-trna synthetase,
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bifunctional aminoacyl-tRNA synthetase
bifunctional glutamate/proline-tRNA ligase
class II prolyl-tRNA synthetase
dual-specificity prolyl-cysteinyl-tRNA synthetase
misleading
dual-specificity prolyl-tRNA synthetase
misleading
Global RNA synthesis factor
glutamyl-/prolyl-tRNA synthetase
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glutamyl-prolyl tRNA synthetase
glutamyl-prolyl-tRNA synthetase
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proline/cysteine-tRNA ligase
prolyl tRNA synthetase
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prolyl-cysteinyl-tRNA synthetase
Prolyl-transfer ribonucleate synthetase
Prolyl-transfer ribonucleic acid synthetase
Prolyl-transfer RNA synthetase
additional information
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cf. EC 6.1.1.17
bifunctional aminoacyl-tRNA synthetase
UniProt
bifunctional aminoacyl-tRNA synthetase
UniProt
bifunctional aminoacyl-tRNA synthetase
UniProt
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bifunctional glutamate/proline-tRNA ligase
UniProt
bifunctional glutamate/proline-tRNA ligase
UniProt
bifunctional glutamate/proline-tRNA ligase
UniProt
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class II prolyl-tRNA synthetase
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class II prolyl-tRNA synthetase
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class II prolyl-tRNA synthetase
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class II prolyl-tRNA synthetase
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class II prolyl-tRNA synthetase
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class II prolyl-tRNA synthetase
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class II prolyl-tRNA synthetase
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EPRS
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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Global RNA synthesis factor
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glutamyl-prolyl tRNA synthetase
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glutamyl-prolyl tRNA synthetase
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glutamyl-prolyl tRNA synthetase
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glutamyl-prolyl tRNA synthetase
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MSMEG_2621
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Pro-tRNA synthetase
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Pro-tRNA synthetase
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ProCysRS
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Proline translase
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Proline--tRNA ligase
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proline/cysteine-tRNA ligase
misleading
proline/cysteine-tRNA ligase
misleading
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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Prolyl RNA synthetase
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prolyl-cysteinyl-tRNA synthetase
misleading
prolyl-cysteinyl-tRNA synthetase
misleading
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleate synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer ribonucleic acid synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-transfer RNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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Prolyl-tRNA synthetase
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ProRS
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proS
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PRS
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
bi uni ping pong mechanism
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
ATP is the first substrate to enter into the reaction sequence and prolyl-tRNA is the last product to dissociate from the enzyme
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
dual substrate specificity
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
enzyme with dual substrate specificity which utilizes L-proline and L-cysteine as substrates, discriminating mechanism
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
induced fit substrate recognition, reaction mechanism, proline binding site structure
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
substrate binding mechanism, the two bases G35 and G36 are sufficient to uniquely identify the cognate tRNAPro
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
the C-terminal extremity folds back into the active site
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
two-step reaction, Asp350 is involved in the pre-transfer editing of alanine
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
one tRNA binds per dimeric enzyme, only 50% of active sites are active
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
one tRNA binds per dimeric enzyme, only 50% of active sites are active
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
class II synthetases are limited by a step prior to aminoacyl transfer
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ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
substrate binding mechanism, the two bases G35 and G36 are sufficient to uniquely identify the cognate tRNAPro
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
adenosine 5'-(beta,gamma-imido)triphosphate + L-proline + tRNAPro
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ATP + 2-selenaproline + tRNAPro
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ATP + 3,4-dehydro-DL-proline + tRNAPro
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ATP + 3-thiaproline + tRNAPro
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ATP + 4-amino-L-proline + tRNAPro
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ATP + 4-difluoro-L-proline + tRNAPro
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ATP + 4-fluoro-L-proline + tRNAPro
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ATP + 4-hydroxy-L-proline + tRNAPro
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ATP + azetidine-2-carboxylic acid + tRNAPro
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ATP + beta-thia-L-proline + tRNAPro
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ATP + cis(exo)-3,4-methano-L-proline + tRNAPro
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ATP + cis-4-hydroxyproline + tRNAPro
AMP + diphosphate + cis-4-hydroxyprolyl-tRNAPro
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ATP + dehydro-L-proline + tRNAPro
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ATP + gamma-thia-L-proline + tRNAPro
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ATP + gamma-thiaproline + tRNAPro
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ATP + L-alanine + tRNAPro
AMP + diphosphate + L-alanyl-tRNAPro
6.1.1.15 proline-tRNA ligase
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