Reference on EC 1.1.1.27 - L-lactate dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Garvie, E.I.
Bacterial lactate dehydrogenases
Microbiol. Rev.
44
106-139
1980
Acholeplasma laidlawii, Actinomyces viscosus, Bacillus caldolyticus, Bacillus subtilis, Bifidobacterium bifidum, Butyrivibrio fibrisolvens, Enterococcus faecalis, Enterococcus faecium, Lactobacillus acidophilus, Lactobacillus brevis, Lactobacillus buchneri, Lactobacillus casei, Lactobacillus curvatus, Lactobacillus dextrinicus, Lactobacillus fermentum, Lactobacillus helveticus, Lactobacillus mesenteroides, Lactobacillus plantarum, Lactobacillus salivarius, Lactobacillus vermiforme, Lactococcus lactis, Lactococcus lactis subsp. cremoris, Lactococcus raffinolactis, Mycoplasma sp., Pediococcus acidilactici, Pediococcus damnosus, Pediococcus inopinatus, Pediococcus pentosaceus, Rothia dentocariosa, Selenomonas ruminantium, Sporosarcina ureae, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus acidominimus, Streptococcus agalactiae, Streptococcus equinus, Streptococcus milleri, Streptococcus mitior, Streptococcus mutans, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus thermophilus, Streptococcus uberis, Tetragenococcus halophilus, Weissella confusa, Weissella viridescens
Manually annotated by BRENDA team
Williams, R.A.; Andrews, P.
Purification of the fructose 1,6-bisphosphate-dependent lactate dehydrogenase from Streptococcus uberis and an investigation of its existence in different forms
Biochem. J.
236
721-727
1986
Streptococcus uberis
Manually annotated by BRENDA team
Place, A.R.; Powers, D.A.
Purification and characterization of the lactate dehydrogenase (LDH-B4) allozymes of Fundulus heteroclitus
J. Biol. Chem.
259
1299-1308
1984
Fundulus heteroclitus
Manually annotated by BRENDA team
Hillier, A.J.; Jago, G.R.
L-Lactate dehydrogenase, FDP-activated, from Streptococcus cremoris
Methods Enzymol.
89
362-367
1982
Lactococcus lactis subsp. cremoris
Manually annotated by BRENDA team
Gordon, G.L.; Doelle, H.W.
Purification, properties and immunological relationship of L (+)-lactate dehydrogenase from Lactobacillus casei
Eur. J. Biochem.
67
543-555
1976
Lactobacillus casei
Manually annotated by BRENDA team
Goetz, F.; Schleifer, K.H.
Purification and properties of a fructose-1,6-diphosphate activated L-lactate dehydrogenase from Staphylococcus epidermidis
Arch. Microbiol.
105
303-312
1975
Staphylococcus epidermidis
Manually annotated by BRENDA team
Mou, L.; Mulvena, D.P.; Jonas, H.A.; Jago, G.R.
Purification and properties of nicotinamide adenine dinucleotide-dependent D- and L-lactate dehydrogenases in a group N streptococcus
J. Bacteriol.
111
392-396
1972
Lactococcus lactis, Lactococcus lactis 760
Manually annotated by BRENDA team
Eichner, R.D.
L(+)-lactate dehydrogenase from Homarus americanus
Methods Enzymol.
89
359-362
1982
Homarus americanus
-
Manually annotated by BRENDA team
Lee, C.Y.; Yuan, J.H.; Goldberg, E.
Lactate dehydrogenase isozymes from mouse
Methods Enzymol.
89
351-358
1982
Mus musculus
Manually annotated by BRENDA team
Oba, K.; Uritani, I.
L-Lactate dehydrogenase isozymes from sweet potato roots
Methods Enzymol.
89
345-351
1982
Ipomoea batatas
-
Manually annotated by BRENDA team
Steinbuechel, A.; Schlegel, H.G.
NAD-linked L(+)-lactate dehydrogenase from the strict aerobe Alcaligenes eutrophus. 1. Purification and properties
Eur. J. Biochem.
130
321-328
1983
Cupriavidus necator
Manually annotated by BRENDA team
Davies, D.D.; Davies, S.
Purification and properties of L(+)-lactate dehydrogenase from potato tubers
Biochem. J.
129
831-839
1972
Solanum tuberosum
Manually annotated by BRENDA team
Pettit, S.M.; Nealon, D.A.; Henderson, A.R.
Purification of lactate dehydrogenase isoenzyme-5 from human liver
Clin. Chem.
27
88-93
1981
Homo sapiens
Manually annotated by BRENDA team
Taguchi, H.; Machida, M.; Matsuzawa, H.; Ohta, T.
Allosteric and kinetic properties of L-lactate dehydrogenase from Thermus caldophilus GK24, an extremely thermophilic bacterium
Agric. Biol. Chem.
49
359-365
1985
Thermus caldophilus, Thermus caldophilus GK24
-
Manually annotated by BRENDA team
Auerbach, G.; Ostendorp, R.; Prade, L.; Korndorfer, I.; Dams, T.; Huber, R.; Jaenicke, R.
Lactate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization
Structure
15
769-781
1998
Thermotoga maritima
Manually annotated by BRENDA team
Oba, K.; Murakami, S.; Uritani, I.
Partial purification and characterization of L-lactate dehydrogenase isozymes from sweet potato roots
J. Biochem.
81
1193-1201
1977
Ipomoea batatas
Manually annotated by BRENDA team
Betsche, T.; Bosach, K.; Gerhardt, B.
L-Lactate dehydrogenase from leaves of Capsella bursa-pastoris (L.) Med. I. Identification and partial characterization
Planta
146
567-574
1979
Capsella bursa-pastoris, Cardamine hirsuta, Lactuca sativa, no activity in Rubus idaeus, no activity in Taraxacum officinale, no activity in Zea mays, Raphanus sativus, Spinacia oleracea, Thlaspi arvense
Manually annotated by BRENDA team
Betsche, T.
L-Lactate dehydrogenase from leaves of higher plants. Kinetics and regulation of the enzyme from lettuce (Lactuca sativa L)
Biochem. J.
195
615-622
1981
Lactuca sativa
Manually annotated by BRENDA team
Hensel, R.; Mayr, U.; Stetter, K.O.; Kandler, O.
Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and Lactobacillus curvatus
Arch. Microbiol.
112
81-93
1977
Lactobacillus casei, Lactobacillus curvatus
Manually annotated by BRENDA team
Hardman, M.J.; Pritchard, G.G.
Kinetics of activation of L-lactate dehydrogenase from Streptococcus faecalis by fructose 1,6-bisphosphate and by metal ions
Biochim. Biophys. Acta
912
185-190
1987
Enterococcus faecalis
Manually annotated by BRENDA team
Allison, N.; Fewson, C.A.
Purification and properties of L-lactate dehydrogenase from Acinetobacter calcoaceticus
FEMS Microbiol. Lett.
36
183-186
1986
Acinetobacter calcoaceticus
-
Manually annotated by BRENDA team
Hardman, M.J.; Crow, V.L.; Cruickshank, D.S.; Pritchard, G.G.
Kinetics of activation of L-lactate dehydrogenase from Streptococcus lactis by fructose 1,6-bisphosphate
Eur. J. Biochem.
146
179-183
1985
Lactococcus lactis
Manually annotated by BRENDA team
Goetz, F.; Schleifer, K.H.
Biochemical properties and the physiological role of the fructose-1,6-bisphosphate activated L-lactate dehydrogenase from Staphylococcus epidermidis
Eur. J. Biochem.
90
555-561
1978
Staphylococcus epidermidis
Manually annotated by BRENDA team
Hensel, R.; Mayr, U.; Fujiki, H.; Kandler, O.
Comparative studies of lactate dehydrogenases in lactic acid bacteria. Amino-acid composition of an active-site region and chemical properties of the L-lactate dehydrogenase of Lactobacillus casei, Lactobacillus curvatus, Lactobacillus plantarum, and Lactobacillus acidophilus
Eur. J. Biochem.
80
83-92
1977
Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus curvatus, Lactobacillus plantarum
Manually annotated by BRENDA team
Crow, V.L.; Pritchard, G.G.
Fructose 1,6-diphosphate-activated L-lactate dehydrogenase from Streptococcus lactis: kinetic properties and factors affecting activation
J. Bacteriol.
131
82-91
1977
Lactococcus lactis
Manually annotated by BRENDA team
Iwata, S.; Yoshida, S.; Ohta, T.
A regular 1:1 complex of two allosteric states in the single crystal of L-lactate dehydrogenase from Bifidobacterium longum
J. Mol. Biol.
236
958-959
1994
Bifidobacterium longum
Manually annotated by BRENDA team
Lee, B.I.; Chang, C.; Cho, S.J.; Han, G.W.; Yu, Y.G.; Eom, S.H.; Suh, S.W.
Lactate dehydrogenase from hyperthermophilic archaeon Methanococcus jannaschii: overexpression, crystallization and preliminary X-ray analysis
Acta Crystallogr. Sect. D
56
81-83
2000
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Ostendorp, R.; Auerbach, G.; Jaenicke, R.
Extremely thermostable L(+)-lactate dehydrogenase from Thermotoga maritima: cloning, characterization, and crystallization of the recombinant enzyme in its tetrameric and octameric state
Protein Sci.
5
862-873
1996
Thermotoga maritima
Manually annotated by BRENDA team
Hewitt, C.O.; Sessions, R.B.; Dafforn, T.R.; Holbrook, J.J.
Protein engineering tests of a homology model of Plasmodium falciparum lactate dehydrogenase
Protein Eng.
10
39-44
1997
Plasmodium falciparum
Manually annotated by BRENDA team
Marchat, L.; Loiseau, P.M.; Petek, F.
Purification and characterization of lactate dehydrogenase isoenzymes 1 and 2 from Molinema dessetae (Nematoda:Filarioidea)
Parasitol. Res.
82
672-680
1996
Molinema dessetae
Manually annotated by BRENDA team
Mendiola, P.; De Costa, J.
The effects of temperature and pH on the kinetic properties of heart muscle lactate dehydrogenase from anuran amphibians
Comp. Biochem. Physiol. B
98
529-534
1991
Epidalea calamita, Pelophylax perezi
-
Manually annotated by BRENDA team
Mulkiewicz, E.; Zietara, M.S.; Stachowiak, K.; Skorkowski, E.F.
Properties of lactate dehydrogenase from the isopod, Saduria entomon
Comp. Biochem. Physiol. B
126
337-346
2000
Saduria entomon
Manually annotated by BRENDA team
Klyachko, O.S.; Ozernyuk, N.D.
Functional and structural properties of lactate dehydrogenase from embryos of different fishes
Comp. Biochem. Physiol. B
119
77-80
1998
Acipenser baerii, Acipenser ruthenus, Carassius auratus, Coregonus autumnalis, Coregonus sardinella, Cyprinus carpio, Danio rerio, Misgurnus fossilis, Oncorhynchus mykiss, Salmo salar
-
Manually annotated by BRENDA team
Holland, L.Z.; McFall-Ngai, M.; Somero, G.N.
Evolution of lactate dehydrogenase-A homologs of barracuda fishes (genus Sphyraena) from different thermal environments: differences in kinetic properties and thermal stability are due to amino acid substitutions outside the active site
Biochemistry
36
3207-3215
1997
Sphyraena argentea (O13276), Sphyraena argentea, Sphyraena barracuda, Sphyraena ensis, Sphyraena helleri, Sphyraena idiastes (O13277), Sphyraena idiastes, Sphyraena lucasana (O13278), Sphyraena lucasana
Manually annotated by BRENDA team
Wu, C.Y.; Chen, S.T.; Chiou, S.H.; Wang, K.T.
Kinetic analysis of duck epsilon-crystallin with L-lactate dehydrogenase activity: determination of kinetic constants and comparison of substrate specificity
Biochem. Biophys. Res. Commun.
186
874-880
1992
Anas platyrhynchos, Gallus gallus
Manually annotated by BRENDA team
Ike, J.; Sangan, P.; Gunasekaran, M.
Purification and properties of lactate dehydrogenase from Nocardia asteroides
Microbios
69
119-127
1992
Nocardia asteroides
Manually annotated by BRENDA team
Cameron, A.D.; Roper, D.I.; Moreton, K.M.; Muirhead, H.; Holbrook, J.J.; Wigley, D.B.
Allosteric activation in Bacillus stearothermophilus lactate dehydrogenase investigated by an X-ray crystallographic analysis of a mutant designed to prevent tetramerization of the enzyme
J. Mol. Biol.
238
615-625
1994
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Iwata, S.; Kamata, K.; Yoshida, S.; Minowa, T.; Ohta, T.
T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric control
Nat. Struct. Biol.
1
176-185
1994
Bifidobacterium longum
Manually annotated by BRENDA team
Bryant, F.O.
Characterization of the fructose 1,6-bisphosphate-activated, L(+)-lactate dehydrogenase from Thermoanaerobacter ethanolicus
J. Enzyme Inhib.
5
235-248
1991
Thermoanaerobacter ethanolicus
Manually annotated by BRENDA team
LeVan, K.M.; Goldberg, E.
Properties of human testis-specific lactate dehydrogenase expressed from Escherichia coli
Biochem. J.
273
587-592
1991
Homo sapiens
Manually annotated by BRENDA team
Savijoki, K.; Palva, A.
Molecular genetic characterization of the L-lactate dehydrogenase gene (ldhL) of Lactobacillus helveticus and biochemical characterization of the enzyme
Appl. Environ. Microbiol.
63
2850-2856
1997
Lactobacillus helveticus
Manually annotated by BRENDA team
Chang, G.G.; Huang, S.M.; Chiou, S.H.
Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin
Arch. Biochem. Biophys.
284
285-291
1991
Anas platyrhynchos, Gallus gallus
Manually annotated by BRENDA team
Brown, W.M.; Yowell, C.A.; Hoard, A.; vander Jagt, T.A.; Hunsaker, L.A.; Deck, L.M.; Royer, R.E.; Piper, R.C.; Dame, J.B.; Makler, M.T.; vander Jagt, D.L.
Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human Malarial parasites
Biochemistry
43
6219-6229
2004
Plasmodium falciparum, Plasmodium falciparum (Q27743), Plasmodium malariae, Plasmodium ovale, Plasmodium vivax, Plasmodium vivax (Q6JH30)
Manually annotated by BRENDA team
Kavanagh, K.L.; Elling, R.A.; Wilson, D.K.
Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use
Biochemistry
43
879-889
2004
Toxoplasma gondii (P90613), Toxoplasma gondii
Manually annotated by BRENDA team
Al-Jassabi, S.
Purification and kinetic properties of skeletal muscle lactate dehydrogenase from the lizard Agama stellio stellio
Biochemistry
67
786-789
2002
Agama stellio stellio
Manually annotated by BRENDA team
Zheng, Y.; Guo, S.; Guo, Z.; Wang, X.
Effects of N-terminal deletion mutation on rabbit muscle lactate dehydrogenase
Biochemistry (Moscow)
69
401-406
2004
Oryctolagus cuniculus
Manually annotated by BRENDA team
Li, C.I.; Lin, Y.H.; Shih, C.L.; Tsaur, J.P.; Chau, L.K.
Sol-gel encapsulation of lactate dehydrogenase for optical sensing of L-lactate
Biosens. Bioelectron.
17
323-330
2002
Gadus morhua
Manually annotated by BRENDA team
Gronczewska, J.; Zietara, M.S.; Biegniewska, A.; Skorkowski, E.F.
Enzyme activities in fish spermatozoa with focus on lactate dehydrogenase isoenzymes from herring Clupea harengus
Comp. Biochem. Physiol. B
134
399-406
2003
Clarias gariepinus, Clupea harengus, Cyprinus carpio
Manually annotated by BRENDA team
Zheng, Y.B.; Wang, Z.; Chen, B.Y.; Wang, X.C.
Multiple effects of chemical reagent on enzyme: o-phthalaldehyde-induced inactivation, dissociation and partial unfolding of lactate dehydrogenase from pig heart
Int. J. Biol. Macromol.
32
191-197
2003
Sus scrofa
Manually annotated by BRENDA team
Russell, P.J.; Williams, A.; Amador, X.; Vargas, R.
Aldolase and actin protect rabbit muscle lactate dehydrogenase from ascorbate inhibition
J. Enzyme Inhib. Med. Chem.
19
91-98
2004
Oryctolagus cuniculus
Manually annotated by BRENDA team
Winter, V.J.; Cameron, A.; Tranter, R.; Sessions, R.B.; Brady, R.L.
Crystal structure of Plasmodium berghei lactate dehydrogenase indicates the unique structural differences of these enzymes are shared across the Plasmodium genus
Mol. Biochem. Parasitol.
131
1-10
2003
Plasmodium berghei, Plasmodium falciparum
Manually annotated by BRENDA team
Bork, S.; Okamura, M.; Boonchit, S.; Hirata, H.; Yokoyama, N.; Igarashi, I.
Identification of Babesia bovis L-lactate dehydrogenase as a potential chemotherapeutical target against bovine babesiosis
Mol. Biochem. Parasitol.
136
165-172
2004
Babesia bovis, Babesia bovis (Q7Z0X7)
Manually annotated by BRENDA team
Madern, D.; Cai, X.; Abrahamsen, M.S.; Zhu, G.
Evolution of Cryptosporidium parvum lactate dehydrogenase from malate dehydrogenase by a very recent event of gene duplication
Mol. Biol. Evol.
21
489-497
2003
Cryptosporidium parvum, Cryptosporidium parvum (Q9GT92)
Manually annotated by BRENDA team
Schaap, D.; Arts, G.; Kroeze, J.; Niessen, R.; Roosmalen-Vos, S.V.; Spreeuwenberg, K.; Kuiper, C.M.; Beek-Verhoeven, N.V.; Kok, J.J.; Knegtel, R.M.; Vermeulen, A.N.
An Eimeria vaccine candidate appears to be lactate dehydrogenase; characterization and comparative analysis
Parasitology
128
603-616
2004
Eimeria acervulina, Eimeria acervulina (Q8I8U5), Eimeria maxima, Eimeria maxima (Q8I8U3), Eimeria tenella, Eimeria tenella (Q8I8U4)
Manually annotated by BRENDA team
Assa, P.; Ozkan, M.; Ozcengiz, G.
Thermostability and regulation of Clostridium thermocellum L-lactate dehydrogenase expressed in Escherichia coli
Ann. Microbiol.
55
193-197
2005
Ruminiclostridium thermocellum
-
Manually annotated by BRENDA team
Ishida, N.; Saitoh, S.; Tokuhiro, K.; Nagamori, E.; Matsuyama, T.; Kitamoto, K.; Takahashi, H.
Efficient production of L-Lactic acid by metabolically engineered Saccharomyces cerevisiae with a genome-integrated L-lactate dehydrogenase gene
Appl. Environ. Microbiol.
71
1964-1970
2005
Bifidobacterium longum, Bifidobacterium longum (P0CW93), Bos taurus
Manually annotated by BRENDA team
Terlecki, G.; Czapinska, E.; Rogozik, K.; Lisowski, M.; Gutowicz, J.
Investigation of the interaction of pig muscle lactate dehydrogenase with acidic phospholipids at low pH
Biochim. Biophys. Acta
1758
133-144
2006
Sus scrofa
Manually annotated by BRENDA team
Ferrer, S.; Silla, E.; Tunon, I.; Oliva, M.; Moliner, V.; Williams, I.H.
Dependence of enzyme reaction mechanism on protonation state of titratable residues and QM level description: lactate dehydrogenase
Chem. Commun. (Camb.)
2005
5873-5875
2005
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Hare, K.M.; Miller, J.H.; Clark, A.G.; Daugherty, C.H.
Total lactate dehydrogenase activity of tail muscle is not cold-adapted in nocturnal lizards from cool-temperate habitats
Comp. Biochem. Physiol. B
142B
438-444
2005
Cyclodina macgregori, Hoplodactylus maculatus, Oligosoma aeneum, Oligosoma nigriplantare polychroma, Oligosoma zelandicum, Woodworthia chrysosireticus
-
Manually annotated by BRENDA team
Vivas, L.; Easton, A.; Kendrick, H.; Cameron, A.; Lavandera, J.L.; Barros, D.; de las Heras, F.G.; Brady, R.L.; Croft, S.L.
Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase
Exp. Parasitol.
111
105-114
2005
Plasmodium falciparum
Manually annotated by BRENDA team
Prachayasittikul, V.; Ljung, S.; Isarankura-Na-Ayudhya, C.; Buelow, L.
NAD(H) recycling activity of an engineered bifunctional enzyme galactose dehydrogenase/lactate dehydrogenase
Int. J. Biol. Sci.
2
10-16
2006
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Chen, Y.; Zhang, H.; Xu, A.; Li, N.; Liu, J.; Liu, C.; Lv, D.; Wu, S.; Huang, L.; Yang, S.; He, D.; Xiao, X.
Elevation of serum L-lactate dehydrogenase B correlated with the clinical stage of lung cancer
Lung Cancer
54
95-102
2006
Homo sapiens
Manually annotated by BRENDA team
Conners, R.; Schambach, F.; Read, J.; Cameron, A.; Sessions, R.B.; Vivas, L.; Easton, A.; Croft, S.L.; Brady, R.L.
Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase
Mol. Biochem. Parasitol.
142
137-148
2005
Plasmodium falciparum
Manually annotated by BRENDA team
Saad, L.O.; Mirandola, S.R.; Maciel, E.N.; Castilho, R.F.
Lactate dehydrogenase activity is inhibited by methylmalonate in vitro
Neurochem. Res.
31
541-548
2006
Bos taurus, Rattus norvegicus
Manually annotated by BRENDA team
Leiblich, A.; Cross, S.S.; Catto, J.W.; Phillips, J.T.; Leung, H.Y.; Hamdy, F.C.; Rehman, I.
Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer
Oncogene
25
2953-2960
2006
Homo sapiens (P07195)
Manually annotated by BRENDA team
Flores, H.; Ellington, A.D.
A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase
Protein Eng. Des. Sel.
18
369-377
2005
Geobacillus stearothermophilus, Geobacillus stearothermophilus (P00344)
Manually annotated by BRENDA team
Svedruzic, Z.M.; Spivey, H.O.
Interaction between mammalian glyceraldehyde-3-phosphate dehydrogenase and L-lactate dehydrogenase from heart and muscle
Proteins
63
501-511
2006
Sus scrofa
Manually annotated by BRENDA team
Viana, R.; Yebra, M.J.; Galan, J.L.; Monedero, V.; Perez-Martinez, G.
Pleiotropic effects of lactate dehydrogenase inactivation in Lactobacillus casei
Res. Microbiol.
156
641-649
2005
Lactobacillus casei
Manually annotated by BRENDA team
Stangl, D.; Wiederkehr, F.; Suter, F.; Zuber, H.
Structure and function of L-lactate dehydrogenase from thermophilic and mesophilic bacteria, V. The complete amino-acid sequence of the mesophilic L-lactate dehydrogenase from Bacillus megaterium
Biol. Chem. Hoppe-SEyler
368
1157-1166
1987
Bacillus megaterium, Bacillus megaterium (P00345), Bacillus megaterium 90 (P00345)
Manually annotated by BRENDA team
Waldvogel, S.; Weber, H.; Zuber, H.
Structure and function of L-lactate dehydrogenase from thermophilic and mesophilic bacteria VII
Biol. Chem. Hoppe-Seyler
368
1391-1399
1987
Bacillus megaterium, Geobacillus stearothermophilus
Manually annotated by BRENDA team
Kouassi, G.K.; Anantheswaran, R.C.; Knabel, S.J.; Floros, J.D.
Effect of high-pressure processing on activity and structure of alkaline phosphatase and lactate dehydrogenase in buffer and milk
J. Agric. Food Chem.
55
9520-9529
2007
Bos taurus
Manually annotated by BRENDA team
Simaga, S.; Abramic, M.; Osmak, M.; Babic, D.; Ilic-Forko, J.
Total tissue lactate dehydrogenase activity in endometrial carcinoma
Int. J. Gynecol. Cancer
18
1272-1278
2008
Homo sapiens
Manually annotated by BRENDA team
Binay, B.; Karagueler, N.G.
Attempting to remove the substrate inhibition of L-lactate dehydrogenase from Bacillus stearothermophilus by site-directed mutagenesis
Appl. Biochem. Biotechnol.
141
265-272
2007
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Ilmen, M.; Koivuranta, K.; Ruohonen, L.; Suominen, P.; Penttila, M.
Efficient production of L-lactic acid from xylose by Pichia stipitis
Appl. Environ. Microbiol.
73
117-123
2007
Lactobacillus helveticus
Manually annotated by BRENDA team
Romero, S.; Merino, E.; Bolivar, F.; Gosset, G.; Martinez, A.
Metabolic engineering of Bacillus subtilis for ethanol production: lactate dehydrogenase plays a key role in fermentative metabolism
Appl. Environ. Microbiol.
73
5190-5198
2007
Bacillus subtilis, Bacillus subtilis BS35
Manually annotated by BRENDA team
Atlante, A.; de Bari, L.; Bobba, A.; Marra, E.; Passarella, S.
Transport and metabolism of L-lactate occur in mitochondria from cerebellar granule cells and are modified in cells undergoing low potassium dependent apoptosis
Biochim. Biophys. Acta
1767
1285-1299
2007
Bos taurus
Manually annotated by BRENDA team
Koiri, R.K.; Trigun, S.K.; Dubey, S.K.; Singh, S.; Mishra, L.
Metal Cu(II) and Zn(II) bipyridyls as inhibitors of lactate dehydrogenase
Biometals
21
117-126
2008
Mus musculus, Mus musculus AKR
Manually annotated by BRENDA team
Pineda, J.R.; Callender, R.; Schwartz, S.D.
Ligand binding and protein dynamics in lactate dehydrogenase
Biophys. J.
93
1474-1483
2007
Homo sapiens
Manually annotated by BRENDA team
Qiu, L.; Gulotta, M.; Callender, R.
Lactate dehydrogenase undergoes a substantial structural change to bind its substrate
Biophys. J.
93
1677-1686
2007
Sus scrofa
Manually annotated by BRENDA team
Lin, D.Q.; Yao, S.J.
Optimizing dye-ligand density with molecular analysis for affinity chromatography of rabbit muscle L-lactate dehydrogenase
Biotechnol. Prog.
23
904-910
2007
Oryctolagus cuniculus
Manually annotated by BRENDA team
Terlecki, G.; Czapi?ska, E.; Hotowy, K.
Ultracentrifugation studies of the location of the site involved in the interaction of pig heart lactate dehydrogenase with acidic phospholipids at low pH. A comparison with the muscle form of the enzyme
Cell. Mol. Biol. Lett.
12
378-395
2007
Sus scrofa
Manually annotated by BRENDA team
Wiwanitkit, V.
Plasmodium and host lactate dehydrogenase molecular function and biological pathways: implication for antimalarial drug discovery
Chem. Biol. Drug Des.
69
280-283
2007
Plasmodium falciparum
Manually annotated by BRENDA team
Fields, P.A.; Strothers, C.M.; Mitchell, M.A.
Function of muscle-type lactate dehydrogenase and citrate synthase of the Galapagos marine iguana, Amblyrhynchus cristatus, in relation to temperature
Comp. Biochem. Physiol. B
150
62-73
2008
Amblyrhynchus cristatus, Amblyrhynchus cristatus (Q0GND9), Iguana iguana, Iguana iguana (Q0GND8)
Manually annotated by BRENDA team
Skory, C.D.; Ibrahim, A.S.
Native and modified lactate dehydrogenase expression in a fumaric acid producing isolate Rhizopus oryzae 99-880
Curr. Genet.
52
23-33
2007
Rhizopus oryzae
Manually annotated by BRENDA team
Paventi, G.; Pizzuto, R.; Chieppa, G.; Passarella, S.
L-Lactate metabolism in potato tuber mitochondria
FEBS J.
274
1459-1469
2007
Solanum tuberosum
Manually annotated by BRENDA team
Shoemark, D.K.; Cliff, M.J.; Sessions, R.B.; Clarke, A.R.
Enzymatic properties of the lactate dehydrogenase enzyme from Plasmodium falciparum
FEBS J.
274
2738-2748
2007
Plasmodium falciparum
Manually annotated by BRENDA team
Gaspar, P.; Neves, A.R.; Shearman, C.A.; Gasson, M.J.; Baptista, A.M.; Turner, D.L.; Soares, C.M.; Santos, H.
The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties - comparative modeling to probe the molecular basis
FEBS J.
274
5924-5936
2007
Lactococcus lactis, Lactococcus lactis (P0C2T6), Lactococcus lactis MG1363 (P0C2T6)
Manually annotated by BRENDA team
Li, X.; Jiang, B.; Pan, B.; Mu, W.; Zhang, T.
Purification and partial characterization of Lactobacillus species SK007 lactate dehydrogenase (LDH) catalyzing phenylpyruvic acid (PPA) conversion into phenyllactic acid (PLA)
J. Agric. Food Chem.
56
2392-2399
2008
Lactobacillus sp., Lactobacillus sp. SK007
Manually annotated by BRENDA team
Lagana, G.; Giacobbe, S.; Bellocco, E.; Mannucci, C.; Galtieri, A.; Ficarra, S.; Kotyk, A.; Leuzzi, U.
Lactate and malate dehydrogenase in the fan-shell associated shrimp, Pontonia pinnophylax (Otto): effects of temperature and urea
J. Exp. Mar. Biol. Ecol.
349
27-34
2007
Pontonia pinnophylax
-
Manually annotated by BRENDA team
Coquelle, N.; Fioravanti, E.; Weik, M.; Vellieux, F.; Madern, D.
Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments
J. Mol. Biol.
374
547-562
2007
Champsocephalus gunnari, Champsocephalus gunnari (O93541), Deinococcus radiodurans, Deinococcus radiodurans (P50933), Thermus thermophilus (Q5SJA1), Thermus thermophilus
Manually annotated by BRENDA team
Lemire, J.; Mailloux, R.J.; Appanna, V.D.
Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1)
PLoS ONE
3
e1550
2008
Homo sapiens
Manually annotated by BRENDA team
Yin, Y.; Kirsch, J.F.
Identification of functional paralog shift mutations: conversion of Escherichia coli malate dehydrogenase to a lactate dehydrogenase
Proc. Natl. Acad. Sci. USA
104
17353-17357
2007
Escherichia coli, Geobacillus stearothermophilus (P00344)
Manually annotated by BRENDA team
Richardson, A.R.; Libby, S.J.; Fang, F.C.
A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity
Science
319
1672-1676
2008
Staphylococcus aureus
Manually annotated by BRENDA team
Kade, I.J.; Paixao, M.W.; Rodrigues, O.E.; Ibukun, E.O.; Braga, A.L.; Zeni, G.; Nogueira, C.W.; Rocha, J.B.
Studies on the antioxidant effect and interaction of diphenyl diselenide and dicholesteroyl diselenide with hepatic delta-aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase
Toxicol. In Vitro
23
14-20
2009
Rattus norvegicus
Manually annotated by BRENDA team
Tokuhiro, K.; Ishida, N.; Nagamori, E.; Saitoh, S.; Onishi, T.; Kondo, A.; Takahashi, H.
Double mutation of the PDC1 and ADH1 genes improves lactate production in the yeast Saccharomyces cerevisiae expressing the bovine lactate dehydrogenase gene
Appl. Microbiol. Biotechnol.
82
883-890
2009
Bos taurus
Manually annotated by BRENDA team
Zhadin, N.; Gulotta, M.; Callender, R.
Probing the role of dynamics in hydride transfer catalyzed by lactate dehydrogenase
Biophys. J.
95
1974-1984
2008
Sus scrofa
Manually annotated by BRENDA team
Deng, H.; Brewer, S.; Vu, D.M.; Clinch, K.; Callender, R.; Dyer, R.B.
On the pathway of forming enzymatically productive ligand-protein complexes in lactate dehydrogenase
Biophys. J.
95
804-813
2008
Sus scrofa
Manually annotated by BRENDA team
Skory, C.; Mertens, J.; Rich, J.
Inhibition of Rhizopus lactate dehydrogenase by fructose 1,6-bisphosphate
Enzyme Microb. Technol.
44
242-247
2009
Rhizopus delemar, Rhizopus delemar RA 99-880, Rhizopus oryzae NRRL 395
-
Manually annotated by BRENDA team
Berwal, R.; Gopalan, N.; Chandel, K.; Prasad, G.B.; Prakash, S.
Plasmodium falciparum: enhanced soluble expression, purification and biochemical characterization of lactate dehydrogenase
Exp. Parasitol.
120
135-141
2008
Plasmodium falciparum
Manually annotated by BRENDA team
Liwak, U.; Ananvoranich, S.
Toxoplasma gondii: Over-expression of lactate dehydrogenase enhances differentiation under alkaline conditions
Exp. Parasitol.
122
155-161
2009
Toxoplasma gondii (P90613), Toxoplasma gondii (Q27797), Toxoplasma gondii
Manually annotated by BRENDA team
Ahmad, R.; Alam, M.; Siddiqui, M.; Hasnain, A.
Adjustments of serum lactate dehydrogenase isoenzymes and their significance in monitoring the treatment in patients with tubercular pyothorax
Indian J. Clin. Biochem.
23
181-185
2008
Homo sapiens
Manually annotated by BRENDA team
Starnes, J.
Effect of storage conditions on lactate dehydrogenase released from perfused hearts
Int. J. Cardiol.
127
114-116
2008
Rattus norvegicus
Manually annotated by BRENDA team
Jin, Q.; Jung, J.Y.; Kim, Y.J.; Eom, H.J.; Kim, S.Y.; Kim, T.J.; Han, N.S.
Production of l-lactate in Leuconostoc citreum via heterologous expression of l-lactate dehydrogenase gene
J. Biotechnol.
144
160-164
2009
Lactobacillus plantarum, Lactobacillus plantarum (P56512)
Manually annotated by BRENDA team
Gorelikov, P.L.; Savelev, S.V.
Lactate dehydrogenase isoenzymes in sympathetic neurons and satellite gliocytes in normal conditions and in blockade of nicotinic cholinoreceptors
Neurosci. Behav. Physiol.
38
817-820
2008
Oryctolagus cuniculus
Manually annotated by BRENDA team
Huang, J.; Huang, Y.; Wu, X.; Du, W.; Yu, X.; Hu, X.
Identification, expression, characterization, and immunolocalization of lactate dehydrogenase from Taenia asiatica
Parasitol. Res.
104
287-293
2009
Taenia asiatica
Manually annotated by BRENDA team
Dong, J.B.; Liu, X.; Li, L.F.; Wu, S.; Su, X.D.
Preliminary X-ray crystallographic analysis of a nitric oxide-inducible lactate dehydrogenase from Staphylococcus aureus
Acta Crystallogr. Sect. F
65
1053-1055
2009
Staphylococcus aureus
Manually annotated by BRENDA team
Joensson, M.; Saleihan, Z.; Nes, I.F.; Holo, H.
Construction and characterization of three lactate dehydrogenase-negative Enterococcus faecalis V583 mutants
Appl. Environ. Microbiol.
75
4901-4903
2009
Enterococcus faecalis
Manually annotated by BRENDA team
Zhou, Q.; Shao, W.L.
Molecular genetic characterization of the thermostable L-lactate dehydrogenase gene (ldhL) of Thermoanaerobacter ethanolicus JW200 and biochemical characterization of the enzyme
Biochemistry (Moscow)
75
526-530
2010
Thermoanaerobacter ethanolicus (B1A4R6), Thermoanaerobacter ethanolicus JW 200 (B1A4R6), Thermoanaerobacter ethanolicus JW 200
Manually annotated by BRENDA team
Granchi, C.; Bertini, S.; Macchia, M.; Minutolo, F.
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials
Curr. Med. Chem.
17
672-697
2010
Bos taurus, Homo sapiens, Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, Plasmodium vivax
Manually annotated by BRENDA team
Echigoya, Y.; Sato, T.; Itou, T.; Endo, H.; Sakai, T.
Molecular characterization and expression pattern of the equine lactate dehydrogenase A and B genes
Gene
447
40-50
2009
Equus caballus (B7XH73), Equus caballus (C6L1K8), Equus caballus
Manually annotated by BRENDA team
Toyoda, K.; Teramoto, H.; Inui, M.; Yukawa, H.
The ldhA gene, encoding fermentative L-lactate dehydrogenase of Corynebacterium glutamicum, is under the control of positive feedback regulation mediated by LldR
J. Bacteriol.
191
4251-4258
2009
Corynebacterium glutamicum
Manually annotated by BRENDA team
Brown, S.A.; Whiteley, M.
Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans
PLoS ONE
4
e7864
2009
Aggregatibacter actinomycetemcomitans, Aggregatibacter actinomycetemcomitans HK1651 and VT1169
Manually annotated by BRENDA team
Zhang, Y.; Gao, X.
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of L-lactate dehydrogenase and its H171C mutant from Bacillus subtilis
Acta Crystallogr. Sect. F
68
63-65
2012
Bacillus subtilis
Manually annotated by BRENDA team
Shaw, A.J.; Covalla, S.F.; Hogsett, D.A.; Herring, C.D.
Marker removal system for Thermoanaerobacterium saccharolyticum and development of a markerless ethanologen
Appl. Environ. Microbiol.
77
2534-2536
2011
Thermoanaerobacterium saccharolyticum (E7CXT1)
Manually annotated by BRENDA team
Argyros, D.A.; Tripathi, S.A.; Barrett, T.F.; Rogers, S.R.; Feinberg, L.F.; Olson, D.G.; Foden, J.M.; Miller, B.B.; Lynd, L.R.; Hogsett, D.A.; Caiazza, N.C.
High ethanol titers from cellulose by using metabolically engineered thermophilic, anaerobic microbes
Appl. Environ. Microbiol.
77
8288-8294
2011
Ruminiclostridium thermocellum, Ruminiclostridium thermocellum DSM 1237
Manually annotated by BRENDA team
Yao, S.; Mikkelsen, M.J.
Metabolic engineering to improve ethanol production in Thermoanaerobacter mathranii
Appl. Microbiol. Biotechnol.
88
199-208
2010
Thermoanaerobacter mathranii, Thermoanaerobacter mathranii BG1
Manually annotated by BRENDA team
Lo, J.; Zheng, T.; Hon, S.; Olson, D.G.; Lynd, L.R.
The bifunctional alcohol and aldehyde dehydrogenase gene, adhE, is necessary for ethanol production in Clostridium thermocellum and Thermoanaerobacterium saccharolyticum
J. Bacteriol.
197
1386-1393
2015
Thermoanaerobacterium saccharolyticum (I3VSF1), Thermoanaerobacterium saccharolyticum, Thermoanaerobacterium saccharolyticum DSM 8691 (I3VSF1)
Manually annotated by BRENDA team
Cripps, R.E.; Eley, K.; Leak, D.J.; Rudd, B.; Taylor, M.; Todd, M.; Boakes, S.; Martin, S.; Atkinson, T.
Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production
Metab. Eng.
11
398-408
2009
Geobacillus thermoglucosidasius, Geobacillus thermoglucosidasius NCIMB 11955
Manually annotated by BRENDA team
Chung, D.; Cha, M.; Guss, A.M.; Westpheling, J.
Direct conversion of plant biomass to ethanol by engineered Caldicellulosiruptor bescii
Proc. Natl. Acad. Sci. USA
111
8931-8936
2014
Caldicellulosiruptor bescii (B9MKZ8), Caldicellulosiruptor bescii, Caldicellulosiruptor bescii DSM 6725 (B9MKZ8)
Manually annotated by BRENDA team