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Literature summary for 1.1.1.27 extracted from

  • Svedruzic, Z.M.; Spivey, H.O.
    Interaction between mammalian glyceraldehyde-3-phosphate dehydrogenase and L-lactate dehydrogenase from heart and muscle (2006), Proteins, 63, 501-511.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + NADH + H+ Sus scrofa D-glyceraldehyde-3-phosphate dehydrogenase and L-lactate dehydrogenase have a functional interaction that can affect NAD+/NADH metabolism and glycolysis in living cells (S)-lactate + NAD+
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Sus scrofa
-
muscle
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + NADH + H+
-
Sus scrofa (S)-lactate + NAD+
-
?
pyruvate + NADH + H+ D-glyceraldehyde-3-phosphate dehydrogenase and L-lactate dehydrogenase have a functional interaction that can affect NAD+/NADH metabolism and glycolysis in living cells Sus scrofa (S)-lactate + NAD+
-
?

Cofactor

Cofactor Comment Organism Structure
NADH
-
Sus scrofa