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Literature summary for 1.1.1.27 extracted from

  • Goetz, F.; Schleifer, K.H.
    Biochemical properties and the physiological role of the fructose-1,6-bisphosphate activated L-lactate dehydrogenase from Staphylococcus epidermidis (1978), Eur. J. Biochem., 90, 555-561.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
fructose 1,6-diphosphate L-lactate dehydrogenase form which is activated by fructose 1,6-diphosphate Staphylococcus epidermidis

General Stability

General Stability Organism
fructose-1,6-diphosphate is necessary to stabilize the tetrameric enzyme form Staphylococcus epidermidis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
4 * 36000, SDS-PAGE Staphylococcus epidermidis
130000
-
tetramer, sucrose density gradient centrifugation in presence of fructose 1,6-diphosphate and NADH Staphylococcus epidermidis

Organism

Organism UniProt Comment Textmining
Staphylococcus epidermidis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + NADH + H+
-
Staphylococcus epidermidis (S)-lactate + NAD+
-
ir

Subunits

Subunits Comment Organism
tetramer 4 * 36000, SDS-PAGE Staphylococcus epidermidis

Cofactor

Cofactor Comment Organism Structure
NADH coenzyme Staphylococcus epidermidis