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Literature summary for 1.1.1.27 extracted from

  • Chung, D.; Cha, M.; Guss, A.M.; Westpheling, J.
    Direct conversion of plant biomass to ethanol by engineered Caldicellulosiruptor bescii (2014), Proc. Natl. Acad. Sci. USA, 111, 8931-8936.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
degradation direct conversion of switchgrass to ethanol without conventional pretreatment of the biomass is accomplished by deletion of lactate dehydrogenase and heterologous expression of a Clostridium thermocellum bifunctional acetaldehyde/alcohol dehydrogenase. Whereas wild-type Caldicellulosiruptor bescii lacks the ability to make ethanol, 70% of the fermentation products in the engineered strain are ethanol (12.8 mM ethanol directly from 2% wt/vol switchgrass) with decreased production of acetate by 38% compared with wild-type Caldicellulosiruptor bescii

Organism

Organism UniProt Comment Textmining
Caldicellulosiruptor bescii B9MKZ8
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Caldicellulosiruptor bescii DSM 6725 B9MKZ8
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Synonyms

Synonyms Comment Organism
LDH
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Caldicellulosiruptor bescii