EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
white adipose tissue |
- |
697625, 761908 |
1.1.1.21 | aldose reductase |
white adipose tissue |
highest enzyme activity is detected in the kidneys, followed by white adipose tissue and the lungs of prehibernating jerboa |
760913 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
white adipose tissue |
moderate activity in female and male rats, decreasing from age 2 months to age 9 months |
655737 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
white adipose tissue |
- |
659398 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
white adipose tissue |
- |
728342, 728552 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
white adipose tissue |
lysyl hydroxylases are expressed in white-adipose tissue of ob/ob mice, overview |
745769 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
white adipose tissue |
lysyl hydroxylases are expressed in white-adipose tissue of ob/ob mice, wherein LH3 levels are increased compared with C57/BL controls. Expression levels of mRNAs corresponding to LH1 (Plod1) and LH3 (Plod3) are both altered in ob/ob mice, in the same direction as the changes in serum levels of adiponectin and the HMW isoforms |
745769 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
white adipose tissue |
- |
746217 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
white adipose tissue |
- |
688772, 698917, 746542 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
white adipose tissue |
high expression level of isozyme SCD1 |
688772 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
white adipose tissue |
isoform SCD-1 |
695472 |
1.2.1.48 | long-chain-aldehyde dehydrogenase |
white adipose tissue |
- |
656268 |
1.2.1.84 | alcohol-forming fatty acyl-CoA reductase |
white adipose tissue |
- |
656242 |
1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) |
white adipose tissue |
- |
710839 |
1.21.99.4 | thyroxine 5'-deiodinase |
white adipose tissue |
- |
700655 |
1.3.8.7 | medium-chain acyl-CoA dehydrogenase |
white adipose tissue |
- |
700516 |
1.3.99.23 | all-trans-retinol 13,14-reductase |
white adipose tissue |
- |
763769 |
1.4.3.21 | primary-amine oxidase |
white adipose tissue |
- |
701612 |
1.4.3.21 | primary-amine oxidase |
white adipose tissue |
very high activity |
705350 |
2.1.1.1 | nicotinamide N-methyltransferase |
white adipose tissue |
- |
756556 |
2.3.1.137 | carnitine O-octanoyltransferase |
white adipose tissue |
high expression of CRAT |
686028 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
white adipose tissue |
- |
688948, 756106 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
white adipose tissue |
highest expression level |
756106 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
white adipose tissue |
low level |
757868 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
white adipose tissue |
moderate expression |
701623 |
2.3.1.16 | acetyl-CoA C-acyltransferase |
white adipose tissue |
weak expression of thiolase B |
658349 |
2.3.1.21 | carnitine O-palmitoyltransferase |
white adipose tissue |
CPT II, L-CPT I |
486577 |
2.3.1.21 | carnitine O-palmitoyltransferase |
white adipose tissue |
CPT II, M-CPT I |
486577 |
2.3.1.21 | carnitine O-palmitoyltransferase |
white adipose tissue |
CPT II, M-CPT I, L-CPT I |
486577 |
2.3.1.21 | carnitine O-palmitoyltransferase |
white adipose tissue |
very low activity |
675740 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
white adipose tissue |
MGAT1 |
486605 |
2.3.1.291 | sphingoid base N-palmitoyltransferase |
white adipose tissue |
- |
754142 |
2.3.1.296 | omega-hydroxyceramide transacylase |
white adipose tissue |
- |
754365 |
2.3.1.48 | histone acetyltransferase |
white adipose tissue |
- |
757517 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
white adipose tissue |
- |
756108 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
white adipose tissue |
physiological significance analyzed in white adipose tissue of mice, soluble lysophosphatidic acid acyltransferase activity, existence of an alternate cytosolic phosphatidic acid biosynthetic pathway |
687752 |
2.3.1.57 | diamine N-acetyltransferase |
white adipose tissue |
expression status of spermidine/spermine N1-acetyltransferase alters body fat accumulation by metabolically modulating tissue acetyl- and malonyl-CoA levels, thereby influencing fatty acid biosynthesis and oxidation |
674903 |
2.3.1.57 | diamine N-acetyltransferase |
white adipose tissue |
low ratio of splice variant SSATX to SSAT mRNA in syngenic rats |
718560 |
2.3.1.7 | carnitine O-acetyltransferase |
white adipose tissue |
- |
686028 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
white adipose tissue |
- |
756689 |
2.3.2.8 | arginyltransferase |
white adipose tissue |
- |
706444 |
2.3.3.8 | ATP citrate synthase |
white adipose tissue |
high expression |
718760 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
white adipose tissue |
lean Wistar rats: mRNA expression levels are maximal in mesenteric WAT (2.01 +/-0.08) followed by inguinal (1.23 +/-0.15), epididymal (0.88 +/-0.13), and retroperitoneal (0.79 +/-0.07) WAT |
692570 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
white adipose tissue |
lean Zucker rats: mRNA expression levels are similar in subcutaneous (inguinal, 1.18 +/-0.33) and visceral (mesenteric (0.99 +/-0.15), retroperitoneal (0.56 +/-0.10), epididymal (1.17 +/-0.14)) WAT |
692570 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
white adipose tissue |
mesenteric, significantly decreased mRNA expression level in cafeteria diet-fed Wistar rats (diet-induced obesity) compared to standard chow diet-fed Wistar rats (control) |
692570 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
white adipose tissue |
significantly reduced mRNA expression level in (fa/fa) Zucker rats (obese) compared to lean Zucker rats (control) and in cafeteria diet-fed Wistar rats (diet-induced obesity) compared to standard chow diet-fed Wistar rats (control) |
692570 |
2.7.1.107 | diacylglycerol kinase (ATP) |
white adipose tissue |
DGKdelta is the most abundant isoform in murine white adipose tissue |
737685 |
2.7.1.52 | fucokinase |
white adipose tissue |
- |
661521 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
white adipose tissue |
- |
673162 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
white adipose tissue |
isozyme PDK2 |
642159 |
2.7.2.3 | phosphoglycerate kinase |
white adipose tissue |
- |
761325 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
white adipose tissue |
inguinal and epididymal, upregulated in brown adipose tissue in comparison to white adipose tissue |
722415 |
2.7.8.27 | sphingomyelin synthase |
white adipose tissue |
- |
-, 737776 |
2.7.8.41 | cardiolipin synthase (CMP-forming) |
white adipose tissue |
- |
760835 |
2.8.2.2 | alcohol sulfotransferase |
white adipose tissue |
of male, but not of female mice. Testosterone-dependent, gender-specific expression of estrogen sulfotransferase in adipose tissue |
692086 |
2.8.2.4 | estrone sulfotransferase |
white adipose tissue |
- |
725979, 760317 |
2.8.2.4 | estrone sulfotransferase |
white adipose tissue |
WAT, high level in females. EST expression in male WAT is testosterone-dependent. Although the basal expression of Est in the female mouse WAT is low, it can be induced in the parametrial fat by testosterone treatment. The induction of EST expression by testosterone in female mice is WAT specific, because testosterone treatment fails to induce the expression of EST in the liver |
-, 760317 |
2.8.2.4 | estrone sulfotransferase |
white adipose tissue |
WAT, high level in male mice |
-, 760988 |
3.1.1.13 | sterol esterase |
white adipose tissue |
- |
714048, 714756 |
3.1.1.3 | triacylglycerol lipase |
white adipose tissue |
- |
707547, 729337, 729345 |
3.1.1.3 | triacylglycerol lipase |
white adipose tissue |
ATGL expression increases dramatically in the subcutaneous adipose during adipose development and maturation, as well as during in vitro adipogenesis. Within the white adipose tissue, ATGL is expressed at higher levels in the adipocyte than in the stromal-vascular fraction |
709776 |
3.1.1.34 | lipoprotein lipase |
white adipose tissue |
- |
-, 653282, 691709, 694184, 729291, 729306, 752181 |
3.1.1.34 | lipoprotein lipase |
white adipose tissue |
highest expression is found in white adipose tissue |
690660 |
3.1.1.34 | lipoprotein lipase |
white adipose tissue |
LPL activity increases in homone-sensitive lipase ko-mice |
652229 |
3.1.1.34 | lipoprotein lipase |
white adipose tissue |
retroperitoneal white adipose tissue lipoprotein lipase activity is rapidly down-regulated in response to acute stress |
681271 |
3.1.1.4 | phospholipase A2 |
white adipose tissue |
AdPLA is highly expressed specifically in white adipose tissue and is induced during preadipocyte differentiation into adipocytes, overview |
693127 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
white adipose tissue |
robust expression of PLA2G7 mRNA |
693526 |
3.1.1.79 | hormone-sensitive lipase |
white adipose tissue |
- |
-, 665964, 677470, 714340, 714840, 730002 |
3.1.1.79 | hormone-sensitive lipase |
white adipose tissue |
adipose triglyceride lipase and hormone-sensitive lipase are responsible for more than 95% of the triglyceride hydrolase activity present in murine white adipose tissue |
680733 |
3.1.2.12 | S-formylglutathione hydrolase |
white adipose tissue |
- |
80992 |
3.1.2.18 | ADP-dependent short-chain-acyl-CoA hydrolase |
white adipose tissue |
low expression of Acot12 |
686028 |
3.1.2.2 | palmitoyl-CoA hydrolase |
white adipose tissue |
expression of isozyme CTE-I and MTE-I |
646203 |
3.1.2.2 | palmitoyl-CoA hydrolase |
white adipose tissue |
strong expression of MTE-I, expression of CTE-I, PTE-Ib, and PTE-Ia |
651962 |
3.1.2.20 | acyl-CoA hydrolase |
white adipose tissue |
- |
751912 |
3.1.2.20 | acyl-CoA hydrolase |
white adipose tissue |
expression of isozyme CTE-I and MTE-I |
646203 |
3.1.3.4 | phosphatidate phosphatase |
white adipose tissue |
- |
680849, 714316 |
3.4.11.7 | glutamyl aminopeptidase |
white adipose tissue |
low enzyme level |
752443 |
3.4.22.38 | cathepsin K |
white adipose tissue |
- |
695943 |
3.5.1.99 | fatty acid amide hydrolase |
white adipose tissue |
- |
720176 |
3.5.4.16 | GTP cyclohydrolase I |
white adipose tissue |
- |
667769 |
4.1.1.32 | phosphoenolpyruvate carboxykinase (GTP) |
white adipose tissue |
WAT |
693786, 694251 |
4.2.1.1 | carbonic anhydrase |
white adipose tissue |
- |
-, 747862 |
4.2.1.1 | carbonic anhydrase |
white adipose tissue |
contains carbonic anhydrase I, III and III |
33541 |
5.3.99.2 | Prostaglandin-D synthase |
white adipose tissue |
- |
747984 |
5.3.99.2 | Prostaglandin-D synthase |
white adipose tissue |
e.g. epididymal |
-, 728575 |
6.2.1.16 | acetoacetate-CoA ligase |
white adipose tissue |
- |
691065 |
6.2.1.16 | acetoacetate-CoA ligase |
white adipose tissue |
AACS gene expression is particularly abundant in white adipose tissue, as it is induced during adipocyte differentiation |
702149 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
white adipose tissue |
- |
675267 |
6.3.1.2 | glutamine synthetase |
white adipose tissue |
- |
673247 |