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Literature summary for 2.3.1.21 extracted from
- Interrelation between long-chain fatty acid oxidation rate and carnitine palmitoyltransferase 1 activity with different isoforms in rat tissues (2005), Life Sci., 77, 435-443.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| KCN | - |
Rattus norvegicus |  |
| Mg2+ | - |
Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | the enzyme is involved in long-chain fatty acid oxidation, overview | ? | - |
? | |
| palmitoyl-CoA + L-carnitine | Rattus norvegicus | - |
CoA + L-palmitoylcarnitine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Sprague-Dawley rats, tissue-specific isozymes L-CPT1 and M-CPT1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brown adipose tissue | M-CPT1 isozyme | Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| liver | L-CPT1 isozyme | Rattus norvegicus | - |
| additional information | activity of tissue-specific isozymes L-CPT1 and M-CPT1, overview | Rattus norvegicus | - |
| muscle | white and red gastrocnemius muscles | Rattus norvegicus | - |
| white adipose tissue | very low activity | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
activity of tissue-specific isozymes L-CPT1 and M-CPT1, overview | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme is involved in long-chain fatty acid oxidation, overview | Rattus norvegicus | ? | - |
? | |
| palmitoyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-palmitoylcarnitine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carnitine palmitoyltransferase 1 | - |
Rattus norvegicus |
| CPT1 | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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