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BRENDA support

Information on EC 3.5.1.99 - fatty acid amide hydrolase

for references in articles please use BRENDA:EC3.5.1.99

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IUBMB Comments

Integral membrane protein, the enzyme is responsible for the catabolism of neuromodulatory fatty acid amides, including anandamide and oleamide, occurs in mammalia.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
fatty acid amide hydrolase, fatty-acid amide hydrolase, anandamide amidohydrolase, endocannabinoid-degrading enzyme, hfaah, oleamide hydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
anandamide + H2O = arachidonic acid + ethanolamine
show the reaction diagram
oleamide + H2O = oleic acid + NH3
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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