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alkalistable alpha-carbonic anhydrase
alpha class carbonic anhydrase
-
-
alpha-carbonic anhydrase isozyme II
-
alpha-class carbonic anhydrase
alpha-type carbonic anhydrase
beta carbonic anhydrase
-
beta-class carbonic anhydrase
bovine carbonic anhydrase II
-
-
cab-type beta-class carbonic anhydrase
-
-
cadmium carbonic anhydrase
-
-
carbonate anhydrase
-
-
-
-
Carbonate dehydratase
-
-
-
-
carbonate dehydratase I
-
carbonate dehydratase III
-
Carbonate dehydratase IX
-
-
-
-
Carbonate dehydratase VA
-
-
-
-
Carbonate dehydratase VB
-
-
-
-
Carbonate dehydratase VII
-
-
-
-
Carbonate dehydratase XII
-
-
-
-
Carbonate dehydratase XIV
-
-
-
-
carbonic acid anhydrase
-
-
-
-
carbonic anhydrase 6
A0A2D1CFJ9
-
carbonic anhydrase cambialistic enzyme
carbonic anhydrase I (CA I) Michigan 1
-
-
carbonic anhydrase isozyme I
-
-
carbonic anhydrase isozyme II
-
-
carbonic anhydrase isozyme III
-
-
carbonic anhydrase isozyme IV
carbonic anhydrase isozyme IX
-
-
carbonic anhydrase type III
-
-
carbonic anhydrase VII
-
-
carbonic anhydrase-II
-
isozyme
carbonic anhydrase-related protein
-
-
carbonic anhydrase-related protein VIII
-
carbonic dehydratase
-
-
-
-
chloroplast carbonic anhydrase
-
-
cytoplasmic carbonic anhydrase
-
dehydratase, carbonate
-
-
-
-
delta carbonic anhydrase
-
delta-carbonic anhydrase
-
diatom carbonic anhydrase
-
-
dual domain-carbonic anhydrase
-
dual-domain carbonic anhydrase
-
erythrocyte carbonic anhydrase
-
external carbonic anhydrase
-
-
extracellular carbonic anhydrase
gamma carbonic anhydrase 1
-
gamma carbonic anhydrase 2
-
gamma carbonic anhydrase-like 1
-
gamma carbonic anhydrase-like 2
-
gamma-class carbonic anhydrase
hCA XIV catalytic domain
-
human carbonic anhydrase
-
-
human carbonic anhydrase I
human carbonic anhydrase II
human carbonic anhydrase III
-
-
human carbonic anhydrase isoenzyme I
-
-
human carbonic anhydrase isoenzyme II
-
-
human carbonic anhydrase IX
-
-
human carbonic anhydrase XII
-
-
human carbonic anhydrase XIV
-
luminal carbonic anhydrase
-
Membrane antigen MN
-
-
-
-
mesohalophilic carbonic anhydrase
-
pentraxin-carbonic anhydrase
-
photosystem II-associated carbonic anhydrase
-
plant-type (beta-class) carbonic anhydrase
-
-
polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase
-
-
RCC-associated antigen G250
-
-
-
-
Renal cell carcinoma-associated antigen G250
-
-
-
-
Salivary carbonic anhydrase
Secreted carbonic anhydrase
secretory carbonic anhydrase
-
-
secretory carbonic anhydrase VI
A0A2D1CFJ9
-
tobacco salicylic acid-binding protein 3
-
-
Tumor antigen HOM-RCC-3.1.3
-
-
-
-
alkalistable alpha-carbonic anhydrase

-
alkalistable alpha-carbonic anhydrase
-
-
alpha carbonic anhydrase

-
alpha carbonic anhydrase
-
-
alpha carbonic anhydrase
-
-
alpha-CA

-
-
alpha-carbonic anhydrase

-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
-
alpha-carbonic anhydrase
-
-
alpha-carbonic anhydrase
-
-
alpha-class carbonic anhydrase

-
-
alpha-class carbonic anhydrase
-
-
alpha-type CA

-
alpha-type carbonic anhydrase

-
-
alpha-type carbonic anhydrase
-
alpha-type carbonic anhydrase
-
alpha-type carbonic anhydrase
-
-
alpha-type carbonic anhydrase
-
alpha-type carbonic anhydrase
-
-
bCA IV

-
-
beta-CA

-
-
beta-carbonic anhydrase

-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
-
beta-carbonic anhydrase
-
beta-carbonic anhydrase
-
beta-class carbonic anhydrase

-
-
beta-class carbonic anhydrase
-
-
-
beta-class carbonic anhydrase
-
-
beta-class carbonic anhydrase
-
beta-class carbonic anhydrase
-
BhCA

-
bsCA I

-
bsCA II

-
CA

-
-
-
-
CA
-
-
649234, 650526, 650548, 652546, 652630, 652634, 652638, 652737, 652744, 652754, 653675
CA 1

-
CA 3

-
-
CA I

-
-
CA II

-
-
649577, 650063, 650282, 652630, 652631, 652636, 652722, 652744, 652754, 696230, 696308, 696737, 696955, 698458, 700632, 702339, 702367, 703554
CA II
-
cytosolic isoform
CA III

-
-
CA IV

-
-
CA IX

-
-
CA VA

-
isoform
CA VA
-
mitochondrial isoform
CA VB

-
isoform
CA VB
-
mitochondrial isoform
CA VI

-
CA VII

-
isoform
CA XII

-
-
CA XIII

-
-
CA XIV

-
isoform
Ca XV

-
-
CA-I

-
CA-II

-
CA-VI

-
-
-
-
CA1

-
-
-
-
CA2

-
-
-
-
CA3

-
CA9

-
-
CAA1

-
CAA2

-
Cab

-
-
CAH3

-
-
CAH7

-
isoform
CAH8

-
isoform
CAI

-
-
CAII

-
-
CAIII

-
-
CAIV

-
-
CAIX

-
-
-
-
Cam

-
-
CamH

-
Carbonate dehydratase VI

-
-
-
-
Carbonate dehydratase VI
-
carbonate hydro-lyase

-
-
carbonate hydro-lyase
-
-
-
carbonate hydrolase

-
-
carbonate hydrolyase

-
-
carbonic anhydrase

-
-
-
-
carbonic anhydrase
-
-
649244, 650269, 650363, 650579, 652630, 652634, 652639, 652722, 701985, 703554, 715948
carbonic anhydrase
-
-
649907, 650062, 650063, 650162, 650271, 650522, 650526, 650548, 650579, 652310, 652546, 652630, 652631, 652634, 652638, 652639, 652722, 652737, 652744, 652754, 696634, 697525, 699234, 699426, 699461, 700632, 702563, 702571, 702654, 702679, 702687, 703005, 703159, 703554, 703558, 705064, 705068, 714423, 714439, 714445, 714459, 714467, 714469, 716412
carbonic anhydrase 1

-
-
carbonic anhydrase 2

-
carbonic anhydrase 3

-
carbonic anhydrase cambialistic enzyme

-
-
carbonic anhydrase cambialistic enzyme
-
-
carbonic anhydrase I

-
carbonic anhydrase I
-
isoform
carbonic anhydrase I
-
isozyme
carbonic anhydrase II

-
-
carbonic anhydrase II
-
-
carbonic anhydrase II
-
-
carbonic anhydrase II
-
-
-
carbonic anhydrase II
-
-
649234, 649724, 649927, 650048, 650271, 650282, 650579, 651596, 665974, 696230, 696308, 698458, 698827, 700971, 702339, 702367, 713954, 714203, 714441, 714467, 714700
carbonic anhydrase II
-
isoform
carbonic anhydrase II
-
isozyme
carbonic anhydrase II
-
-
carbonic anhydrase III

-
-
carbonic anhydrase III
-
-
carbonic anhydrase III
-
isozyme
carbonic anhydrase III
-
the enzyme possesses only low carbon dioxide hydratase activity
carbonic anhydrase III
-
-
carbonic anhydrase isozyme IV

-
-
carbonic anhydrase isozyme IV
-
-
carbonic anhydrase IV

-
-
carbonic anhydrase IV
-
-
carbonic anhydrase IV
-
isozyme
carbonic anhydrase IV
-
-
carbonic anhydrase IV
-
-
-
carbonic anhydrase IX

-
-
carbonic anhydrase V

-
-
carbonic anhydrase VI

-
-
carbonic anhydrase VI
-
-
carbonic anhydrase VI
-
-
-
carbonic anhydrase VI
A0A2D1CFJ9
-
carbonic anhydrase XII

-
-
carbonic anhydrase XIII

-
-
carbonic anhydrase XIII
-
isoform
carbonic anhydrase XIII
-
carbonic anhydrase XIII
-
-
carbonic anhydrase XIV

-
carbonic anhydrase XIV
-
-
carbonic anhydrase XV

-
-
carbonic anhydrase XV
-
isoform
carbonic anhydrase-I

-
isozyme
CcmM

-
CDCA1

-
-
CmCA

-
CpsCA

-
CpsCAgamma

-
cynT

-
DVU_1777

-
eCA

-
-
eCA
Chaetoceros vixvisibilis
-
-
extracellular carbonic anhydrase

-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
Chaetoceros vixvisibilis
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
extracellular carbonic anhydrase
-
-
gamma-CA

-
gamma-carbonic anhydrase

-
gamma-carbonic anhydrase
-
gamma-carbonic anhydrase
-
-
gamma-carbonic anhydrase
-
-
gamma-carbonic anhydrase
-
-
gamma-carbonic anhydrase
-
-
gamma-carbonic anhydrase
-
-
-
gamma-carbonic anhydrase
-
gamma-carbonic anhydrase
-
gamma-carbonic anhydrase
-
-
gamma-class carbonic anhydrase

-
-
gamma-class carbonic anhydrase
-
hCA I

-
-
hCA I
-
678660, 678676, 678681, 678696, 678712, 747699, 748133, 748307, 748308, 748316, 748317, 749204
HCA II

-
HCA II
-
-
649234, 650048, 650139, 650526, 650548, 651596, 652310, 652546, 652634, 652722, 652737, 652754, 713954
HCA II
-
678267, 678660, 678676, 678681, 678696, 678712, 713951, 746925, 747699, 747974, 748133, 748307, 748308, 748316, 748317
hCA III

-
-
hCA IV

-
-
hCA IX

-
-
hCA XII

-
-
hCAII

-
-
HICA

-
-
human carbonic anhydrase I

-
-
human carbonic anhydrase I
-
human carbonic anhydrase II

-
-
human carbonic anhydrase II
-
Ice-CA

-
-
mCA XIII

-
-
Nce103

-
-
NstCcmM209

-
-
PERMA_1443

-
PgiCAb

-
PGJ_00014320

-
PMCA

-
Rv1284

-
-
Rv3273

-
Salivary carbonic anhydrase

-
-
-
-
Salivary carbonic anhydrase
-
SazCA

-
-
Secreted carbonic anhydrase

-
-
-
-
Secreted carbonic anhydrase
-
SspCA

-
SULAZ_0541

-
TacA

-
Tcru

-
Tcr_1545

-
Theam_1576

-
TweCA

-
-
additional information

HICA is a type II member of the beta-carbonic anhydrase family
additional information
-
the enzyme from Methanosorcina thermophila belongs to the gamma class carbonic anhydrases
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
H2CO3 = CO2 + H2O

carbonic anhydrase III is limited in rate by a step occuring outside the actual interconversion of CO2 and HCO3- and involving a change in bonding to hydrogen exchangeable with solvent water
-
H2CO3 = CO2 + H2O
zinc-hydroxide mechanism, rate-determining H+ transfer step in catalytic mechanism
-
H2CO3 = CO2 + H2O
mechanism
-
H2CO3 = CO2 + H2O
-
-
-
-
H2CO3 = CO2 + H2O
the rate limiting step in catalysis of bicarbonate dehydration by HCA II is an intramolecular proton transfer from His64 to the zinc-bound hydroxide
-
H2CO3 = CO2 + H2O
reaction mechanism, overview
H2CO3 = CO2 + H2O
reaction mechanism, model of the active site designed on the basis of the X-ray crystal structure, proposed for both metal ions similar reaction pathways consisting in the nucleophilic attack by the metal bound hydroxide to the carbon dioxide with bicarbonate formation, in a next internal rotation of this last fragment, and then in the formation of a species ready for the product removal, overview
-
H2CO3 = CO2 + H2O
reaction mechanism, model of the active site designed on the basis of the X-ray crystal structure, proposed for both metal ions similar reaction pathways consisting in the nucleophilic attack by the metal bound hydroxide to the carbon dioxide with bicarbonate formation, in a next internal rotation of this last fragment, and then in the formation of a species ready for the product removal, overview
-
H2CO3 = CO2 + H2O
interconversion of CO2 and water to bicarbonate and a proton. The general catalysis of CA is a metal-hydroxide ping-pong mechanism composed of two independent steps. The first step of catalysis is initiated by nucleophilic attack on the carbon of CO2 by the metal-bound hydroxide to yield bicarbonate, which is subsequently displaced by a water molecule. The second step is the removal of a proton from the now metal-bound water via an ordered water network and a residue acting as a weak base, which is typically a His at the opening of the active site
H2CO3 = CO2 + H2O
reaction mechanism, analysis of the restoring step of the carbonic anhydrase catalytic cycle for natural and promiscuous substrates, natural HCO3-x02and promiscuous H2NCOHN- products, catalytic reaction mechanism, NPT molecular dynamics simulations, overview
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
D9PU79
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
-
H2CO3 = CO2 + H2O
interconversion of CO2 and water to bicarbonate and a proton. The general catalysis of CA is a metal-hydroxide ping-pong mechanism composed of two independent steps. The first step of catalysis is initiated by nucleophilic attack on the carbon of CO2 by the metal-bound hydroxide to yield bicarbonate, which is subsequently displaced by a water molecule. The second step is the removal of a proton from the now metal-bound water via an ordered water network and a residue acting as a weak base, which is typically a His at the opening of the active site
-
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
-
H2CO3 = CO2 + H2O
the catalytic mechanism for the CO2 hydration reaction consists of two steps. In the first step a zinc-bound hydroxide leads the nucleophilic attack on a CO2 molecule with formation of bicarbonate bound to the zinc ion, which is then substituted by a water molecule. The second step, the rate limiting one, consists of the regeneration of the enzyme reactive species, the zinc-bound hydroxide, via a proton transfer reaction, which occurs from the zinc-bound water molecule to the external buffer. This process is generally assisted by an enzyme residue which acts as proton shuttle
-
-
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
3-nitrophenyl acetate + H2O
3-nitrophenol + acetate
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + ?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
-
-
-
?
4-nitrophenyl sulfate + H2O
4-nitrophenol + sulfate
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
-
-
-
-
?
additional information
?
-
2-nitrophenyl acetate + H2O

2-nitrophenol + acetate
-
-
-
r
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
-
-
-
?
4-nitrophenyl acetate + H2O

4-nitrophenol + ?
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + ?
-
-
-
?
4-nitrophenyl acetate + H2O

4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
-
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
Elephas trogontherii
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
carbonylsulfide + H2O

?
-
-
-
-
?
carbonylsulfide + H2O
?
-
-
-
-
?
CO2 + H2O

H2CO3
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
Chaetoceros vixvisibilis
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
Coccomyxa sp.
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
periplasmic alpha-carbonic anhydrase activity of Helicobacter pylori is essential for acid acclimation
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
696230, 696308, 696613, 696634, 696737, 696955, 697525, 698458, 698469, 698814, 698827, 699227, 699246, 699426, 699461, 699957, 700140, 700410, 700632, 700971, 701131, 702339, 702367, 702470, 702518, 702563, 702571, 702654, 702679, 702687, 703005, 703159, 703554, 703558, 705064, 705068, 706515 -
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
among the seven known isozymes carbonic anhydrase III is the least efficient in catalytic hydration of CO2
-
r
CO2 + H2O
H2CO3
-
roles for residues 7, 62, and 67 in finetuning the properties of His64 for optimal proton transfer in catalysis
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
Lupinus sp.
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
Melilotus sp.
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
kinetics of SspCA is characterized in terms of first order CO2 hydration rate according to a procedure based on CO2 absorption tests in a stirred cell apparatus
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
kinetics of SspCA is characterized in terms of first order CO2 hydration rate according to a procedure based on CO2 absorption tests in a stirred cell apparatus
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
CO2 + H2O
H2CO3
-
-
-
-
r
CO2 + H2O
H2CO3
-
-
-
-
?
COS + H2O

CO2 + H2S
-
-
-
-
?
COS + H2O
CO2 + H2S
-
-
-
-
?
CS2 + 2 H2O

CO2 + 2 H2S
-
-
-
-
?
CS2 + 2 H2O
CO2 + 2 H2S
-
-
-
-
?
H2CO3

CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
plays a role in various physiological functions, including interconversion between CO2 and HCO3- in intermediary metabolism, facilitated diffusion of CO2, pH homeostasis and ion transport
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
Caminibacter sp.
-
-
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
?
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
bicarbonate binding mode and binding structure, overview
-
-
r
H2CO3
CO2 + H2O
-
-
-
-
r
H2CO3
CO2 + H2O
-
CsoSCA converts HCO3- to CO2 for use in carbon fixation by ribulose-bisphosphate carboxylase/oxygenase
-
-
?
H2CO3
CO2 + H2O
-
-
-
-
?