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Information on EC 3.1.2.20 - acyl-CoA hydrolase

for references in articles please use BRENDA:EC3.1.2.20

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IUBMB Comments

Broad specificity for medium- to long-chain acyl-CoA. Insensitive to NAD+ (cf. EC 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase)

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes

Synonyms
acyl-coa hydrolase, them2, type ii thioesterase, them1, acot11, them4, acot13, thioesterase superfamily member 2, te ii, thioesterase 2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an acyl-CoA + H2O = CoA + a carboxylate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
acyl-CoA hydrolysis, firefly bioluminescence, jasmonic acid biosynthesis, palmitoleate biosynthesis IV (fungi and animals)