EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
prostate gland |
- |
705206 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
prostate gland |
21% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
prostate gland |
- |
668432, 699847, 761757 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
prostate gland |
presence of 11beta-hydroxysteroid dehydrogenase mRNA transcripts and protein in all tissues of the reproductive tract examined, but cortison-cortisol interconversion is undetectable in the corpus and cauda epididymides, vas deferens, vesicular and prostate glands |
695090 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
- |
285953, 699847 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
presence of 11beta-hydroxysteroid dehydrogenase mRNA transcripts and protein in all tissues of the reproductive tract examined, but cortison-cortisol interconversion is undetectable in the corpus and cauda epididymides, vas deferens, vesicular and prostate glands |
695090 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
prostate gland |
androgen-sensitive cancer cells LNCaP and hormone-independent PC3 cells, enzyme expression is induced by steroids |
285939 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
prostate gland |
very low expression level |
669380 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
- |
654934, 670033, 686263, 762074 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
epithelial cells of the acini and stromal cells |
675190 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
moderate expression |
685803 |
1.3.1.124 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] |
prostate gland |
- |
759825 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
prostate gland |
20alpha-HSD mRNA lower expressed |
285997 |
1.14.14.29 | 25/26-hydroxycholesterol 7alpha-hydroxylase |
prostate gland |
CYP7B1 is overexpressed in high-grade prostatic intraepithelial neoplasia and in prostate cancer |
689846 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
prostate gland |
- |
711934 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
prostate gland |
epithelial, endothelial and smooth muscle cells |
669701 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
prostate gland |
PDE11 |
668987 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
prostate gland |
PDE11A2 |
668989 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
prostate gland |
PDE11A4 |
668989 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
prostate gland |
PDE11A4, strong antibody staining in the glandular epithelium |
668988 |
1.1.1.209 | 3(or 17)alpha-hydroxysteroid dehydrogenase |
prostate gland |
- |
389547 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
prostate gland |
isozyme 17beta-HSD5 |
675983 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
- |
-, 657354, 668281, 670738, 712201 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
prostate cancer cell |
670032 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
prostate cancer cell lines |
669566 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
type 2 5alpha-reductase mRNA is predominantly expressed in the prostate gland |
662726 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
ventral prostate |
669811 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
very low activity |
391397 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
- |
390655, 390656, 390657, 396200, 396204, 396217, 396219, 396220, 656681, 675475, 675683, 686575, 687218, 688684, 688718, 688719, 689849 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
hyperplastic |
396202, 396208, 396211 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
studies in DU 145 cells, a human cell-line of low androgen sensitivity derived from a cerebral metastasis of an ephithelial prostate cancer |
396218, 396223 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
type-2 5alpha-reductase is only found in prostate and other genital tissues, enhancement of type-1 5alpha-reductase is enhanced in prostate cancer |
684816 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
ventral |
396192, 396193, 396209 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
ventral prostate, activity of both isoform I and II is increased after treatment with oxytocin |
655351 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
- |
287211, 287212 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
androgen target tissues |
673341 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
prostate gland |
- |
724711 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
prostate gland |
- |
347987, 668392, 676812 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
prostate gland |
epithelial cells, but not the stromal cells or endothelial cells |
688137 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
prostate gland |
in primary prostate stromal cells, co-localization with RODH like 3alpha/17beta-HSD, EC 1.1.1.239 |
676002 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
prostate gland |
- |
389529, 389531, 389540, 389547, 389551 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
prostate gland |
epithelial cells, but not the stromal cells or endothelial cells |
688137 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
prostate gland |
- |
763756 |
7.6.2.3 | ABC-type glutathione-S-conjugate transporter |
prostate gland |
- |
747222 |
3.1.3.2 | acid phosphatase |
prostate gland |
- |
134698, 134741, 134750, 134758, 134759, 134788, 664939 |
3.1.3.2 | acid phosphatase |
prostate gland |
age- and sex-dependent enzyme expression level, overview |
664547 |
3.1.3.2 | acid phosphatase |
prostate gland |
carcinoma prostate, benign prostate hypertrophy, normal prostate |
134726 |
3.1.3.2 | acid phosphatase |
prostate gland |
isoenzyme PAP-I and PAP-II |
134726 |
3.1.3.2 | acid phosphatase |
prostate gland |
low in fetal tissue, during development activity gradually increases |
134690 |
4.2.1.3 | aconitate hydratase |
prostate gland |
- |
33810 |
4.2.1.3 | aconitate hydratase |
prostate gland |
epithelium |
33810 |
4.2.1.3 | aconitate hydratase |
prostate gland |
mitochondrial isozyme plays the key role in the bioenergetic theory of malignant transformation of the prostate |
696168 |
3.4.24.B9 | ADAM9 endopeptidase |
prostate gland |
elevated level of enzyme in malignant compared to benign tissue. Increase in enzyme protein and mRNA upon exposure of prostate cells to stress conditions. Inhibition of stress-induction of enzyme by actinomycin D and cycloheximide |
668164 |
3.4.24.B11 | ADAMTS1 endopeptidase |
prostate gland |
prostate stromal cell |
670737 |
3.13.2.1 | adenosylhomocysteinase |
prostate gland |
- |
-, 137149 |
4.1.1.50 | adenosylmethionine decarboxylase |
prostate gland |
- |
4667, 4668, 4669, 4682, 714391, 714392 |
4.1.1.50 | adenosylmethionine decarboxylase |
prostate gland |
ventral |
4679 |
2.7.1.147 | ADP-specific glucose/glucosamine kinase |
prostate gland |
- |
723169 |
1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
prostate gland |
- |
655563 |
2.8.2.2 | alcohol sulfotransferase |
prostate gland |
- |
738296, 761169, 761662, 761881 |
2.8.2.2 | alcohol sulfotransferase |
prostate gland |
prostate epithelial cells, prostate benign prostatic hyperplasia, prostate adenocarcinoma and LNCaP prostate adenocarcinoma cells |
675680 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
prostate gland |
- |
655948, 686531 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
prostate gland |
- |
686531 |
3.1.3.1 | alkaline phosphatase |
prostate gland |
- |
94574 |
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
prostate gland |
- |
697796 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
- |
663582, 665035, 666797, 677438, 680093, 682625, 701605 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
from healthy persons, and after cystoprostatectomy and radical prostatectomy, overview, enzyme activity in prostate is increased from normal looking epithelial cells and atrophy, to prostatic intraepithelial neoplasia, away from and adjacent to prostate carcinoma, the expression in prostate carcinoma is slightly lower in cystoprostatectomy compared to radical prostatectomy specimen, immunohistochemic detection, overview |
677439 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
from patients with prostate carcinoma, atypia and benign hyperplasia |
703387 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
high grade prostatic intraepithelial neoplasia |
666796 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
low expression level |
680073 |
1.13.11.33 | arachidonate 15-lipoxygenase |
prostate gland |
- |
659222, 674995, 676263 |
2.3.2.8 | arginyltransferase |
prostate gland |
- |
488023 |
2.3.1.56 | aromatic-hydroxylamine O-acetyltransferase |
prostate gland |
- |
487253 |
4.1.1.28 | aromatic-L-amino-acid decarboxylase |
prostate gland |
total RNA is isolated from tissue specimens from benign prostate hyperplasia and prostate cancer patients |
691846 |
2.1.1.137 | arsenite methyltransferase |
prostate gland |
moderate expression |
758507 |
2.1.1.137 | arsenite methyltransferase |
prostate gland |
weak expression |
758507 |
2.3.1.5 | arylamine N-acetyltransferase |
prostate gland |
- |
675601 |
2.3.1.5 | arylamine N-acetyltransferase |
prostate gland |
NAT1 is strongly localized to androgen-positive epithelium in human prostate |
672920 |
6.1.1.12 | aspartate-tRNA ligase |
prostate gland |
- |
744436 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
prostate gland |
- |
713952 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
prostate gland |
low levels of BCO mRNA |
438228 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
prostate gland |
low expression level of CaM-K1delta |
664928 |
1.14.15.18 | calcidiol 1-monooxygenase |
prostate gland |
- |
675686 |
4.2.1.1 | carbonic anhydrase |
prostate gland |
- |
33547 |
4.2.1.1 | carbonic anhydrase |
prostate gland |
contains carbonic anhydrase I, II and III |
33541 |
1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
prostate gland |
prostate connective tissue |
720152 |
3.4.22.41 | cathepsin F |
prostate gland |
- |
137259 |
3.4.22.38 | cathepsin K |
prostate gland |
low activity |
30368 |
3.4.22.42 | cathepsin O |
prostate gland |
- |
137267 |
3.5.1.23 | ceramidase |
prostate gland |
- |
719608 |
2.7.11.12 | cGMP-dependent protein kinase |
prostate gland |
transition zone, distribution of cGKI |
673462 |
3.4.21.42 | complement subcomponent C1s |
prostate gland |
- |
753047 |
5.3.1.21 | corticosteroid side-chain-isomerase |
prostate gland |
- |
2655 |
3.4.13.18 | cytosol nonspecific dipeptidase |
prostate gland |
- |
36115 |
1.1.2.4 | D-lactate dehydrogenase (cytochrome) |
prostate gland |
- |
740447 |
1.3.1.70 | DELTA14-sterol reductase |
prostate gland |
TM7SF2 |
672378 |
3.1.21.7 | deoxyribonuclease V |
prostate gland |
- |
730709 |
1.3.1.1 | dihydropyrimidine dehydrogenase (NAD+) |
prostate gland |
- |
685782 |
3.4.14.5 | dipeptidyl-peptidase IV |
prostate gland |
- |
697519 |
1.14.11.33 | DNA oxidative demethylase |
prostate gland |
high ABH3 mRNA levels |
723671 |