EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
5.3.1.21 | corticosteroid side-chain-isomerase |
prostate gland |
- |
2655 |
4.1.1.50 | adenosylmethionine decarboxylase |
prostate gland |
- |
4667, 4668, 4669, 4682, 714391, 714392 |
4.1.1.50 | adenosylmethionine decarboxylase |
prostate gland |
ventral |
4679 |
4.2.1.47 | GDP-mannose 4,6-dehydratase |
prostate gland |
- |
5732 |
3.4.21.73 | u-Plasminogen activator |
prostate gland |
- |
29578 |
3.4.22.38 | cathepsin K |
prostate gland |
low activity |
30368 |
4.2.1.1 | carbonic anhydrase |
prostate gland |
contains carbonic anhydrase I, II and III |
33541 |
4.2.1.1 | carbonic anhydrase |
prostate gland |
- |
33547 |
4.2.1.11 | phosphopyruvate hydratase |
prostate gland |
- |
33611 |
4.2.1.3 | aconitate hydratase |
prostate gland |
- |
33810 |
4.2.1.3 | aconitate hydratase |
prostate gland |
epithelium |
33810 |
3.4.13.18 | cytosol nonspecific dipeptidase |
prostate gland |
- |
36115 |
3.4.13.9 | Xaa-Pro dipeptidase |
prostate gland |
- |
36115 |
3.4.17.3 | lysine carboxypeptidase |
prostate gland |
benign hypertrophy |
36402 |
3.4.23.3 | gastricsin |
prostate gland |
- |
36848, 668809, 718005 |
3.4.15.1 | peptidyl-dipeptidase A |
prostate gland |
- |
755108, 81211 |
3.1.3.1 | alkaline phosphatase |
prostate gland |
- |
94574 |
3.1.1.4 | phospholipase A2 |
prostate gland |
- |
133865 |
3.1.3.2 | acid phosphatase |
prostate gland |
low in fetal tissue, during development activity gradually increases |
134690 |
3.1.3.2 | acid phosphatase |
prostate gland |
- |
134698, 134741, 134750, 134758, 134759, 134788, 664939 |
3.1.3.2 | acid phosphatase |
prostate gland |
carcinoma prostate, benign prostate hypertrophy, normal prostate |
134726 |
3.1.3.2 | acid phosphatase |
prostate gland |
isoenzyme PAP-I and PAP-II |
134726 |
3.1.3.4 | phosphatidate phosphatase |
prostate gland |
isoenzyme PAP2a |
134884 |
3.1.3.9 | glucose-6-phosphatase |
prostate gland |
- |
134945 |
3.13.2.1 | adenosylhomocysteinase |
prostate gland |
- |
-, 137149 |
3.4.17.21 | Glutamate carboxypeptidase II |
prostate gland |
prostrate carcinoma cell line LNCaP |
137218, 137219, 137226, 137230 |
3.4.22.41 | cathepsin F |
prostate gland |
- |
137259 |
3.4.22.42 | cathepsin O |
prostate gland |
- |
137267 |
3.5.4.3 | guanine deaminase |
prostate gland |
- |
209590 |
1.1.1.14 | L-iditol 2-dehydrogenase |
prostate gland |
ventral and dorsal |
285881 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
prostate gland |
androgen-sensitive cancer cells LNCaP and hormone-independent PC3 cells, enzyme expression is induced by steroids |
285939 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
- |
285953, 699847 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
prostate gland |
20alpha-HSD mRNA lower expressed |
285997 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
- |
287211, 287212 |
1.1.1.95 | phosphoglycerate dehydrogenase |
prostate gland |
- |
287528 |
1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
prostate gland |
- |
288202 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
prostate gland |
- |
349718 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
prostate gland |
- |
389529, 389531, 389540, 389547, 389551 |
1.1.1.209 | 3(or 17)alpha-hydroxysteroid dehydrogenase |
prostate gland |
- |
389547 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
- |
390655, 390656, 390657, 396200, 396204, 396217, 396219, 396220, 656681, 675475, 675683, 686575, 687218, 688684, 688718, 688719, 689849 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
very low activity |
391397 |
1.5.1.6 | formyltetrahydrofolate dehydrogenase |
prostate gland |
moderate FDH mRNA level |
392350 |
1.8.3.2 | thiol oxidase |
prostate gland |
small amounts |
393063 |
1.8.4.2 | protein-disulfide reductase (glutathione) |
prostate gland |
DU145 carcinoma |
394854 |
1.8.1.9 | thioredoxin-disulfide reductase |
prostate gland |
isoform TR1 |
394945 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
ventral |
396192, 396193, 396209 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
hyperplastic |
396202, 396208, 396211 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
studies in DU 145 cells, a human cell-line of low androgen sensitivity derived from a cerebral metastasis of an ephithelial prostate cancer |
396218, 396223 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
prostate gland |
low levels of BCO mRNA |
438228 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
prostate gland |
- |
438404 |
1.13.11.5 | homogentisate 1,2-dioxygenase |
prostate gland |
- |
439387 |
2.3.1.56 | aromatic-hydroxylamine O-acetyltransferase |
prostate gland |
- |
487253 |
2.3.2.2 | gamma-glutamyltransferase |
prostate gland |
- |
487898, 487932 |
2.3.2.2 | gamma-glutamyltransferase |
prostate gland |
secretion into seminal plasma |
487940 |
2.3.2.8 | arginyltransferase |
prostate gland |
- |
488023 |
2.4.1.17 | glucuronosyltransferase |
prostate gland |
- |
488786, 488790, 693011 |
2.4.1.69 | type 1 galactoside alpha-(1,2)-fucosyltransferase |
prostate gland |
prostatic epithelial cells derived from patients with benign prostatic hyperplasia and from patients with prostatic cancer |
489361 |
2.5.1.16 | spermidine synthase |
prostate gland |
- |
-, 489861, 489870, 489872, 489876, 639699, 639700, 639702, 639709, 661300, 661303 |
2.5.1.22 | spermine synthase |
prostate gland |
- |
-, 489861, 489867, 489870, 489872 |
2.7.10.2 | non-specific protein-tyrosine kinase |
prostate gland |
activity is significantly lower in prostate cancer tissue after androgen withdrawal and is also low in prostate cancer cell lines |
491949 |
2.4.2.28 | S-methyl-5'-thioadenosine phosphorylase |
prostate gland |
- |
637526, 637540, 736923 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
prostate gland |
IGnT is highly expressed in adult prostata |
638567 |
2.5.1.16 | spermidine synthase |
prostate gland |
ventral |
-, 639701, 639705 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
prostate gland |
isozyme PI3K-C2alpha inbasal epithelium and fibromuscular stroma, no isozyme PI3K-C2beta and isozyme p85 |
645046 |
3.4.21.35 | tissue kallikrein |
prostate gland |
low content |
647332 |
3.4.21.35 | tissue kallikrein |
prostate gland |
prostate-specific |
647531 |
3.4.21.B6 | prostasin |
prostate gland |
epithelial cell and duct |
651845 |
1.1.1.300 | NADP-retinol dehydrogenase |
prostate gland |
- |
654687, 656064, 762061 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
- |
654934, 670033, 686263, 762074 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
ventral prostate, activity of both isoform I and II is increased after treatment with oxytocin |
655351 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
prostate gland |
16.5% of the activity in liver |
655483 |
1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
prostate gland |
- |
655563 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
prostate gland |
- |
655948, 686531 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
- |
-, 657354, 668281, 670738, 712201 |
1.8.1.9 | thioredoxin-disulfide reductase |
prostate gland |
- |
658795, 701340 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
prostate gland |
Northern blot analysis of human tissues |
659136 |
1.13.11.33 | arachidonate 15-lipoxygenase |
prostate gland |
- |
659222, 674995, 676263 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
prostate gland |
mRNA for CYP4F8 detected |
660409 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
type 2 5alpha-reductase mRNA is predominantly expressed in the prostate gland |
662726 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
- |
663582, 665035, 666797, 677438, 680093, 682625, 701605 |
3.4.21.B10 | neurosin |
prostate gland |
splice variant 3 is preferentially expressed in spinal cord, mammary, and salivary glands and to lesser extent in protstate |
663841 |
3.1.3.2 | acid phosphatase |
prostate gland |
age- and sex-dependent enzyme expression level, overview |
664547 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
prostate gland |
low expression level of CaM-K1delta |
664928 |
2.7.11.24 | mitogen-activated protein kinase |
prostate gland |
- |
665029, 706581 |
3.4.21.77 | semenogelase |
prostate gland |
concentration of enzyme in nonprostatic tissue represents less than 1% of the amount in normal prostate |
665230 |
3.1.3.4 | phosphatidate phosphatase |
prostate gland |
- |
665805 |
4.1.1.17 | ornithine decarboxylase |
prostate gland |
- |
665902 |
3.1.3.16 | protein-serine/threonine phosphatase |
prostate gland |
low enzyme expression level |
666301 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
prostate gland |
high grade prostatic intraepithelial neoplasia |
666796 |
3.4.17.21 | Glutamate carboxypeptidase II |
prostate gland |
prostate form of the enzyme is termed prostate-specific membrane antigen |
667114, 670817 |
3.4.24.7 | interstitial collagenase |
prostate gland |
enzyme expression is significantly stronger in the epithelium than in the stroma |
667214 |
3.4.21.B45 | kallikrein 14 |
prostate gland |
- |
667860 |
3.4.21.B12 | prostase |
prostate gland |
predominant expression in basal cells of prostate gland |
668144 |
3.4.17.21 | Glutamate carboxypeptidase II |
prostate gland |
epithelial cells |
668154 |
3.4.24.B9 | ADAM9 endopeptidase |
prostate gland |
elevated level of enzyme in malignant compared to benign tissue. Increase in enzyme protein and mRNA upon exposure of prostate cells to stress conditions. Inhibition of stress-induction of enzyme by actinomycin D and cycloheximide |
668164 |
1.8.3.2 | thiol oxidase |
prostate gland |
- |
668207 |
3.4.21.B12 | prostase |
prostate gland |
healthy prostate, highest amount of enzyme |
668285 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
prostate gland |
- |
668432, 699847, 761757 |
3.4.24.56 | insulysin |
prostate gland |
activity and amount of enzyme decrease in the cytosolic fraction with castration and increase with testpsterone treatment |
668492 |
3.4.23.45 | memapsin 1 |
prostate gland |
- |
668810 |