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Information on EC 1.8.4.2 - protein-disulfide reductase (glutathione)

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IUBMB Comments
Reduces insulin and some other proteins.
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Word Map
  • 1.8.4.2
  • insulin-degrading
  • 5.3.4.1
  • dsbas
  • thioredoxin-like
  • tautomerase
  • whib-like
  • d-dopachrome
  • disulphide-isomerase
  • 125i-insulin
  • medicine
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
glutathione-insulin transhydrogenase, whib1, dsba2, mif-2, dsba1, thiol disulfide oxidoreductase, insulin reductase, gsh-insulin transhydrogenase, thiol:protein-disulfide oxidoreductase, cata protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 glutathione + protein-disulfide = glutathione-disulfide + protein-dithiol
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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