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Information on EC 3.4.17.21 - Glutamate carboxypeptidase II

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.21 Glutamate carboxypeptidase II
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Word Map
  • 3.4.17.21
  • tomography
  • lncap
  • positron
  • metastases
  • psma-targeted
  • node
  • tracer
  • prostatectomy
  • modal
  • psma-positive
  • neovasculature
  • biodistribution
  • radiotracer
  • psma-expressing
  • gleason
  • 68ga-psma
  • castration-resistant
  • radionuclide
  • radiopharmaceutical
  • theranostic
  • radioligands
  • pelvic
  • 68ga-labeled
  • metabotropic
  • aptamer
  • suvmax
  • mcrpc
  • multiparametric
  • restaging
  • dosimetry
  • spect
  • urea-based
  • oligometastatic
  • n-acetylaspartate
  • mpmri
  • hormone-refractory
  • radiosynthesis
  • enzalutamide
  • medicine
  • nonprostatic
  • extraprostatic
  • tomography-computed
  • tumor-to-background
  • 18f-labeled
  • radioimmunotherapy
  • pet-ct
  • positron-emission
  • abiraterone
  • pharmacology
  • analysis
  • diagnostics
  • drug development
  • tumor-to-blood
  • radiometals
  • antigen-based
The enzyme appears in viruses and cellular organisms
Reaction Schemes
release of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly-gamma-glutamates
Synonyms
100 kDa ileum brush border membrane protein, Acetylaspartylglutamate dipeptidase, altered meristem program1, AMP1, Dipeptidase, acetylaspartylglutamate, EC 3.4.19.8, FGCP, folate hydrolase 1, FOLH1, Folylpoly-gamma-glutamate carboxypeptidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
release of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly-gamma-glutamates
show the reaction diagram
PATHWAY SOURCE
PATHWAYS