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Information on EC 3.4.17.21 - Glutamate carboxypeptidase II

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.21 Glutamate carboxypeptidase II
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Word Map
  • 3.4.17.21
  • tomography
  • positron
  • metastases
  • lncap
  • psma-targeted
  • node
  • tracer
  • prostatectomy
  • modal
  • castration-resistant
  • psma-positive
  • biodistribution
  • androgen
  • radiotracer
  • 68ga-psma
  • radiotherapy
  • gleason
  • neovasculature
  • radionuclide
  • radioligands
  • psma-expressing
  • theranostic
  • radiopharmaceutical
  • pelvic
  • mcrpc
  • suvmax
  • multiparametric
  • 68ga-labeled
  • restaging
  • oligometastatic
  • dosimetry
  • spect
  • urea-based
  • pet-ct
  • nonprostatic
  • n-acetylaspartate
  • tomography-computed
  • hormone-refractory
  • enzalutamide
  • 18f-labeled
  • positron-emission
  • radioimmunotherapy
  • medicine
  • abiraterone
  • mpmri
  • extraprostatic
  • castrate-resistant
  • drug development
  • nuclide
  • pharmacology
  • tumor-to-background
  • radiometals
  • analysis
  • diagnostics
  • patient-based
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
release of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly-gamma-glutamates
Synonyms
100 kDa ileum brush border membrane protein, Acetylaspartylglutamate dipeptidase, altered meristem program1, AMP1, Dipeptidase, acetylaspartylglutamate, EC 3.4.19.8, FGCP, folate hydrolase, folate hydrolase 1, FOLH1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
release of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly-gamma-glutamates
show the reaction diagram
PATHWAY SOURCE
PATHWAYS