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BRENDA support

Literature summary for 3.4.21.77 extracted from

  • Olsson, A.Y.; Bjartell, A.; Lilja, H.; Lundwall, A.
    Expression of prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in ileum and other extraprostatic tissues (2005), Int. J. Cancer, 113, 290-297.
    View publication on PubMed

Application

Application Comment Organism
diagnostics concentration of enzyme in nonprostatic tissue represents less than 1% of the amount in normal prostate. Thus enzyme released from sources other than the prostate may add to the plasma pool, but it is unlikely that nonprostatic enzyme normally can interfere with the diagnosis of prostate cancer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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isoform prostate specific antigen
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Source Tissue

Source Tissue Comment Organism Textmining
epithelium secretory epithelial cells, concentration of enzyme in nonprostatic tissue represents less than 1% of the amount in normal prostate Homo sapiens
-
ileum Paneth cells, pronounced expression of enzyme Homo sapiens
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prostate gland concentration of enzyme in nonprostatic tissue represents less than 1% of the amount in normal prostate Homo sapiens
-