Information on EC 1.14.14.94 - leukotriene-B4 20-monooxygenase

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IUBMB Comments
A cytochrome P-450 (heme-thiolate) protein found in mammals.
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Word Map
  • 1.14.14.94
  • warfarin
  • vkorc1
  • cyp2c9
  • anticoagulant
  • arachidonic
  • dosing
  • pharmacogenetic
  • 20-hete
  • 20-hydroxyeicosatetraenoic
  • cyp4fs
  • cyp4a11
  • omega-hydroxylation
  • epoxide
  • eicosanoids
  • cyp3a5
  • interindividual
  • acenocoumarol
  • pharmacogenomics
  • thromboembolic
  • non-genetic
  • cyp1b1
  • omega-oxidation
  • 17-octadecynoic
  • epoxyeicosatrienoic
  • pharmacogenes
  • genotype-guided
  • lipoxins
The enzyme appears in viruses and cellular organisms
Synonyms
CYP4 omega-hydroxylases, CYP4A11, CYP4F11, CYP4F12, CYP4F13, CYP4F14, CYP4F15, CYP4F16, CYP4F17, CYP4F18, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
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PATHWAY SOURCE
PATHWAYS
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