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Literature summary for 4.2.1.1 extracted from
- Carbonic anhydrase: isoenzymes, properties, distribution, and functional significance (1972), Biol. Rev., 47, 465-513.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 3 | - |
CO2 | 25°C, pH 7.05, low activity carbonic anhydrase | Homo sapiens |  |
| 4 | - |
CO2 | 25°C, pH 7.0, low activity carbonic anhydrase | Homo sapiens | |
| 6 | - |
CO2 | 0°C, pH 7.0, high activity carbonic anhydrase | Oryctolagus cuniculus | |
| 8 | - |
CO2 | 0°C, pH 7.0, high activity carbonic anhydrase | Homo sapiens | |
| 8 | - |
CO2 | 25°C, pH 7.07, high activity carbonic anhydrase | Petroselinum crispum | |
| 9 | - |
CO2 | 25°C, pH 7.0, low activity carbonic anhydrase | Rattus norvegicus | |
| 9 | - |
CO2 | 0.5°C, pH 7.1, high activity carbonic anhydrase | Bos taurus | |
| 9 | - |
CO2 | 25°C, pH 7.0, high activity carbonic anhydrase | Homo sapiens | |
| 10 | - |
CO2 | - |
Homo sapiens | |
| 10 | - |
CO2 | 0°C, pH 7.2, high activity carbonic anhydrase | Cavia porcellus | |
| 11 | - |
CO2 | 0°C, pH 7.0, high activity carbonic anhydrase | Rattus norvegicus | |
| 12 | - |
CO2 | 25°C, pH 7.0, high activity carbonic anhydrase | Bos taurus | |
| 14 | - |
CO2 | 25°C, pH 7.05, high activity carbonic anhydrase | Homo sapiens | |
| 21 | - |
CO2 | 25°C, pH 7.2, low activity carbonic anhydrase | Bos taurus | |
| 22 | - |
CO2 | - |
Homo sapiens | |
| 22 | - |
CO2 | 0°C, pH 7.2, low activity carbonic anhydrase | Cavia porcellus | |
| 27 | - |
CO2 | 0°C, pH 7.0, low activity carbonic anhydrase | Oryctolagus cuniculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Cavia porcellus | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Mammalia | - |
two distinct kinds of isoenzymes: high activity carbonic anhydrase and low activity carbonic anhydrase | - |
| Oryctolagus cuniculus | - |
- |
- |
| Petroselinum crispum | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cecum | mucosa | Cavia porcellus | - |
| cecum | mucosa | Mammalia | - |
| choroid plexus | - |
Mammalia | - |
| erythrocyte | - |
Cavia porcellus | - |
| erythrocyte | - |
Mammalia | - |
| erythrocyte | - |
Homo sapiens | - |
| erythrocyte | - |
Bos taurus | - |
| erythrocyte | - |
Oryctolagus cuniculus | - |
| eye | retina, lens, ciliary body | Mammalia | - |
| gall bladder | - |
Mammalia | - |
| gall bladder | mucosa | Cavia porcellus | - |
| glia | - |
Mammalia | - |
| ileum | mucosa | Cavia porcellus | - |
| jejunum | mucosa | Cavia porcellus | - |
| prostate gland | - |
Mammalia | - |
| prostate gland | - |
Rattus norvegicus | - |
| right colon mucosa | - |
Cavia porcellus | - |
| right colon mucosa | - |
Mammalia | - |
| rumen epithelium | - |
Mammalia | - |
| salivary gland | - |
Mammalia | - |
| stomach | gastric mucosa | Cavia porcellus | - |
| stomach | gastric mucosa | Mammalia | - |
| uterine endometrium | - |
Mammalia | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CO2 + H2O | - |
Cavia porcellus | H2CO3 | - |
? | |
| CO2 + H2O | - |
Mammalia | H2CO3 | - |
? | |
| CO2 + H2O | - |
Homo sapiens | H2CO3 | - |
? | |
| CO2 + H2O | - |
Rattus norvegicus | H2CO3 | - |
? | |
| CO2 + H2O | - |
Bos taurus | H2CO3 | - |
? | |
| CO2 + H2O | - |
Oryctolagus cuniculus | H2CO3 | - |
? | |
| CO2 + H2O | - |
Petroselinum crispum | H2CO3 | - |
? | |
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