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Literature summary for 2.4.1.69 extracted from

  • Marker, P.C.; Stephan, J.P.; Lee, J.; Bald, L.; Mather, J.P.; Cunha, G.R.
    Fucosyltransferase1 and H-type complex carbohydrates modulate epithelial cell proliferation during prostatic branching morphogenesis (2001), Dev. Biol., 233, 95-108.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDP-L-fucose + beta-D-galactosyl-R Homo sapiens fucosyltransferase 1 may contribute to pathological prostatic growth GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
 ?
GDP-L-fucose + beta-D-galactosyl-R Rattus norvegicus fucosyltransferase 1 may contribute to pathological prostatic growth GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BPH-1 cell
-
 Homo sapiens
-
DU-145 cell
-
 Homo sapiens
-
ND-1 cell
-
 Homo sapiens
-
NRP-152 cell
-
 Rattus norvegicus
-
NRP-154 cell
-
 Rattus norvegicus
-
PC-3 cell
-
 Homo sapiens
-
prostate gland prostatic epithelial cells derived from patients with benign prostatic hyperplasia and from patients with prostatic cancer Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-L-fucose + beta-D-galactosyl-R
-
 Homo sapiens GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
 ?
GDP-L-fucose + beta-D-galactosyl-R
-
 Rattus norvegicus GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
 ?
GDP-L-fucose + beta-D-galactosyl-R fucosyltransferase 1 may contribute to pathological prostatic growth Homo sapiens GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
 ?
GDP-L-fucose + beta-D-galactosyl-R fucosyltransferase 1 may contribute to pathological prostatic growth Rattus norvegicus GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
 ?