Inhibitors | Comment | Organism | Structure |
---|---|---|---|
antipain | 50% inhibition at 0.0064 mM | Homo sapiens | |
Aprotinin | 50% inhibition at 0.0000018 mM | Homo sapiens | |
benzamidine | 50% inhibition at 0.86 mM | Homo sapiens | |
leupeptin | 50% inhibition at 0.1 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
108 | - |
D-Pro-Phe-Arg 7-amido-4-methylcoumarin | pH 9, 25°C | Homo sapiens | |
108 | - |
D-Pro-Phe-Arg 7-amido-4-methylcoumarin | D-Pro-Phe-Arg-7-amido-4-methylcoumarin | Homo sapiens | |
255 | - |
D-Val-Leu-Arg-7-amido-4-methylcoumarin | pH 9, 25°C | Homo sapiens | |
717 | - |
Z-Gly-Pro-Arg-7-amido-4-trifluoromethylcoumarin | pH 9, 25°C | Homo sapiens | |
827 | - |
D-Phe-Phe-Arg 7-amido-4-methylcoumarin | pH 9, 25°C | Homo sapiens | |
827 | - |
D-Phe-Phe-Arg 7-amido-4-methylcoumarin | D-Phe-Phe-Arg-7-amido-4-methylcoumarin | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Protein + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
homogeneity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bronchus | - |
Homo sapiens | - |
colon | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
additional information | no activity in brain, muscle, testis, ventricle, atrium and aorta | Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
prostate gland | epithelial cell and duct | Homo sapiens | - |
salivary gland | - |
Homo sapiens | - |
seminal plasma | - |
Homo sapiens | - |
urine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Gly-Pro-Arg-7-amido-4-trifluoromethylcoumarin | - |
Homo sapiens | benzyloxycarbonyl-Gly-Pro-Arg + 7-amino-4-trifluoromethylcoumarin | - |
? | |
D-Phe-Phe-Arg 4-methylcoumarin 7-amide | - |
Homo sapiens | ? | - |
? | |
D-Phe-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | D-Phe-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
D-Pro-Phe-Arg 4-methylcoumarin 7-amide | - |
Homo sapiens | ? | - |
? | |
D-Pro-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | D-Pro-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
D-Val-Leu-Arg 4-methylcoumarin 7-amide | - |
Homo sapiens | ? | - |
? | |
D-Val-Leu-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | D-Val-Leu-Arg + 7-amino-4-methylcoumarin | - |
? | |
Protein + H2O | - |
Homo sapiens | ? | - |
? | |
Z-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Z-Gly-Pro-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
S01.159 | Merops ID | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.068 | - |
D-Pro-Phe-Arg-7-amido-4-methylcoumarin | pH 9, 25°C | Homo sapiens | |
0.105 | - |
D-Val-Leu-Arg-7-amido-4-methylcoumarin | pH 9, 25°C | Homo sapiens | |
0.287 | - |
Z-Gly-Pro-Arg-7-amido-4-trifluoromethylcoumarin | pH 9, 25°C | Homo sapiens | |
0.29 | - |
D-Phe-Phe-Arg-7-amido-4-methylcoumarin | pH 9, 25°C | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8.5 | 9.5 | 50% activity at pH 8.5 and pH 9.5 | Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | isoelectric focusing, pH gradient 3.5-10 | - |
4.5 |