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BRENDA support

Information on EC 1.3.1.70 - DELTA14-sterol reductase

for references in articles please use BRENDA:EC1.3.1.70

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IUBMB Comments

This enzyme acts on a range of steroids with a 14(15)-double bond.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
lamin b receptor, erg24, tm7sf2, 14-reductase, sterol c-14 reductase, dhcr14, fackel, c14sr, delta14-reductase, fk-j3158, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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