Any feedback?
Literature summary for 2.7.1.147 extracted from
- Expression and role in glycolysis of human ADP-dependent glucokinase (2012), Mol. Cell. Biochem., 364, 131-145.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.29 | - |
D-glucose | pH 7.0, 37°C | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| bladder | - |
Homo sapiens | - |
| brain | - |
Homo sapiens | - |
| breast | - |
Homo sapiens | - |
| breast adenocarcinoma cell | - |
Homo sapiens | - |
| colon | - |
Homo sapiens | - |
| colorectal adenocarcinoma cell | - |
Homo sapiens | - |
| glioblastoma cell | - |
Homo sapiens | - |
| kidney | - |
Homo sapiens | - |
| leukemia cell | - |
Homo sapiens | - |
| lung | - |
Homo sapiens | - |
| lung adenocarcinoma cell | - |
Homo sapiens | - |
| lymphoma cell | - |
Homo sapiens | - |
| melanoma cell | - |
Homo sapiens | - |
| ovary | - |
Homo sapiens | - |
| pancreas | - |
Homo sapiens | - |
| pancreatic adenocarcinoma cell | - |
Homo sapiens | - |
| prostate adenocarcinoma cell | - |
Homo sapiens | - |
| prostate gland | - |
Homo sapiens | - |
| uterus | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + D-glucose | enzyme shows substrate inhibition at high glucose concentrations | Homo sapiens | AMP + D-glucose 6-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADP-dependent glucokinase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | overexpression or suppression of ADPGK does not show any relevant effect | Homo sapiens |
| metabolism | human ADPGK catalyses ADP-dependent phosphorylation of glucose in vitro | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
