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Information on EC 3.4.21.42 - complement subcomponent C1s

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.42 complement subcomponent C1s
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Cleavage of Arg-/-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-/-Lys bond in complement component C2 to form C2a and C2b: the "classical" pathway C3 convertase
Synonyms
masp-2, c1 esterase, c1-esterase, mbl-associated serine protease-2, complement c1s, c1s protease, complement component c1s, complement protease, serine protease c1s, protease c1s, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Cleavage of Arg-/-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-/-Lys bond in complement component C2 to form C2a and C2b: the "classical" pathway C3 convertase
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