EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
U-937 cell |
- |
739864 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
U-937 cell |
- |
739864 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
U-937 cell |
- |
655663 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
U-937 cell |
NADP+-dependent isocitrate dehydrogenase may play an important role in regulating the apoptosis induced by ionizing radiation |
687547 |
1.11.1.24 | thioredoxin-dependent peroxiredoxin |
U-937 cell |
0.0027 mg Prx I per mg of soluble protein Prx I, 0.0005 mg Prx II per mg of soluble protein, less than 0.0003 mg Prx III per mg of soluble protein, 0.0005 mg Prx V per mg of soluble protein and 0.0013 mg Prx VI per mg of soluble protein |
655756 |
1.11.1.6 | catalase |
U-937 cell |
- |
699926 |
1.13.11.27 | 4-hydroxyphenylpyruvate dioxygenase |
U-937 cell |
a monoblast-like human histiocytic lymphoma cell line |
742056 |
1.13.11.34 | arachidonate 5-lipoxygenase |
U-937 cell |
- |
711301, 711633 |
1.13.11.34 | arachidonate 5-lipoxygenase |
U-937 cell |
leukemic monocyte cells |
741862 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
U-937 cell |
- |
654926, 686867, 695602 |
1.3.3.4 | protoporphyrinogen oxidase |
U-937 cell |
- |
686939 |
1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
U-937 cell |
promyelomonocytic, histiocytic |
390923 |
1.5.3.16 | spermine oxidase |
U-937 cell |
monocytic cell line |
741582 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
U-937 cell |
- |
688753 |
2.1.1.319 | type I protein arginine methyltransferase |
U-937 cell |
- |
756861 |
2.3.1.147 | glycerophospholipid arachidonoyl-transferase (CoA-independent) |
U-937 cell |
- |
718983 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
U-937 cell |
- |
736546 |
2.3.1.24 | sphingosine N-acyltransferase |
U-937 cell |
- |
753169 |
2.3.1.48 | histone acetyltransferase |
U-937 cell |
- |
675963, 686174, 702554, 719084, 736055, 756850 |
2.3.1.48 | histone acetyltransferase |
U-937 cell |
leukemia cell line |
675311, 686096 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
U-937 cell |
- |
737183, 758268 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
U-937 cell |
- |
704940 |
2.3.2.23 | E2 ubiquitin-conjugating enzyme |
U-937 cell |
- |
759535 |
2.3.3.8 | ATP citrate synthase |
U-937 cell |
- |
735597 |
2.4.1.212 | hyaluronan synthase |
U-937 cell |
- |
704558 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
U-937 cell |
- |
704615 |
2.4.2.4 | thymidine phosphorylase |
U-937 cell |
- |
660558, 685026, 689244 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
U-937 cell |
- |
722730 |
2.4.3.2 | beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase |
U-937 cell |
- |
745270 |
2.7.1.107 | diacylglycerol kinase (ATP) |
U-937 cell |
levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages |
640373 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
U-937 cell |
- |
671954 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
U-937 cell |
monocyte |
-, 640862, 640880, 645044 |
2.7.1.74 | deoxycytidine kinase |
U-937 cell |
- |
662521, 721969 |
2.7.1.91 | sphingosine kinase |
U-937 cell |
- |
703611, 704087, 738839 |
2.7.1.91 | sphingosine kinase |
U-937 cell |
N,N-dimethyl-D-erythro-sphingosine induces apoptotic cell death via modulation of mitochondrial membrane potential, c-Jun N-terminal protein kinase, p38 MAP kinase, extracellular signal-regulated kinase, and Akt kinase, but not through inhibition of sphingosine kinase or protein -kinase C in U937 cells |
689845 |
2.7.10.1 | receptor protein-tyrosine kinase |
U-937 cell |
- |
691595, 693453 |
2.7.10.2 | non-specific protein-tyrosine kinase |
U-937 cell |
- |
676883 |
2.7.11.1 | non-specific serine/threonine protein kinase |
U-937 cell |
- |
723080 |
2.7.11.1 | non-specific serine/threonine protein kinase |
U-937 cell |
isozyme PKNalpha |
662053 |
2.7.11.10 | IkappaB kinase |
U-937 cell |
- |
722690 |
2.7.11.15 | beta-adrenergic-receptor kinase |
U-937 cell |
high expression of beta-ARK 1 |
490989 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
U-937 cell |
- |
691612 |
2.7.11.20 | elongation factor 2 kinase |
U-937 cell |
- |
739836 |
2.7.11.24 | mitogen-activated protein kinase |
U-937 cell |
- |
705321 |
2.7.11.30 | receptor protein serine/threonine kinase |
U-937 cell |
a myelo-monocytic leukemic cell line |
691532 |
2.7.8.27 | sphingomyelin synthase |
U-937 cell |
- |
668494 |
2.8.2.30 | [heparan sulfate]-glucosamine 3-sulfotransferase 3 |
U-937 cell |
- |
738745, 761164 |
3.1.1.13 | sterol esterase |
U-937 cell |
- |
714756 |
3.1.1.2 | arylesterase |
U-937 cell |
- |
749762 |
3.1.1.25 | 1,4-lactonase |
U-937 cell |
- |
749762 |
3.1.1.34 | lipoprotein lipase |
U-937 cell |
- |
708067 |
3.1.22.1 | deoxyribonuclease II |
U-937 cell |
- |
696131 |
3.1.3.4 | phosphatidate phosphatase |
U-937 cell |
promonocytic leukemia macrophage cell line |
680707 |
3.1.4.11 | phosphoinositide phospholipase C |
U-937 cell |
- |
679976 |
3.1.4.12 | sphingomyelin phosphodiesterase |
U-937 cell |
- |
135180, 716445 |
3.1.4.3 | phospholipase C |
U-937 cell |
human monocytic leukemia cell line |
652678 |
3.1.4.4 | phospholipase D |
U-937 cell |
- |
693458 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
U-937 cell |
- |
711630 |
3.2.1.17 | lysozyme |
U-937 cell |
- |
171034 |
3.2.1.46 | galactosylceramidase |
U-937 cell |
- |
697390, 714597 |
3.2.1.51 | alpha-L-fucosidase |
U-937 cell |
- |
655418 |
3.2.2.23 | DNA-formamidopyrimidine glycosylase |
U-937 cell |
- |
682052 |
3.3.2.10 | soluble epoxide hydrolase |
U-937 cell |
- |
708573 |
3.4.11.1 | leucyl aminopeptidase |
U-937 cell |
- |
665925 |
3.4.11.2 | membrane alanyl aminopeptidase |
U-937 cell |
- |
663607, 683119, 683747, 683894, 701354 |
3.4.11.2 | membrane alanyl aminopeptidase |
U-937 cell |
promonocytic cell line |
665244, 665955, 665958 |
3.4.14.2 | dipeptidyl-peptidase II |
U-937 cell |
- |
667557 |
3.4.18.1 | cathepsin X |
U-937 cell |
- |
664854, 664856, 683533 |
3.4.18.1 | cathepsin X |
U-937 cell |
monocytic |
693808 |
3.4.21.20 | cathepsin G |
U-937 cell |
- |
36523 |
3.4.21.37 | leukocyte elastase |
U-937 cell |
- |
700135 |
3.4.21.38 | coagulation factor XIIa |
U-937 cell |
FXII binds tightly to U-937 cells |
696541 |
3.4.21.69 | Protein C (activated) |
U-937 cell |
- |
752736 |
3.4.21.73 | u-Plasminogen activator |
U-937 cell |
- |
717222 |
3.4.21.73 | u-Plasminogen activator |
U-937 cell |
a histiocytic lymphoma cell line |
710133 |
3.4.21.73 | u-Plasminogen activator |
U-937 cell |
lymphoma cells |
709091 |
3.4.21.76 | Myeloblastin |
U-937 cell |
- |
665647 |
3.4.21.76 | Myeloblastin |
U-937 cell |
cell associated PR3 levels are lower than in neutrophils, thus sensitivity of the indirect immunofluorescence test is lower |
686188 |
3.4.22.1 | cathepsin B |
U-937 cell |
- |
701273 |
3.4.22.49 | separase |
U-937 cell |
- |
732703, 755097 |
3.4.22.55 | caspase-2 |
U-937 cell |
- |
663875, 665952 |
3.4.22.56 | caspase-3 |
U-937 cell |
- |
647613 |
3.4.22.56 | caspase-3 |
U-937 cell |
myeloid leukemia cells |
699937 |
3.4.22.56 | caspase-3 |
U-937 cell |
promyelocytic leukemia |
647609 |
3.4.22.61 | caspase-8 |
U-937 cell |
- |
708090, 710388, 753244 |
3.4.22.62 | caspase-9 |
U-937 cell |
treated with doxorubicin (2, 2.5, and 0.25 microg/ml in PBS), doxorubicin-induced cell death |
699440 |
3.4.22.63 | caspase-10 |
U-937 cell |
- |
666516 |
3.4.23.5 | cathepsin D |
U-937 cell |
- |
36914 |
3.4.24.7 | interstitial collagenase |
U-937 cell |
mononuclear phagocytes |
709234 |
3.4.24.7 | interstitial collagenase |
U-937 cell |
presence of high glucose levels and interferon gamma in culture medium have a synergistic effect on the expression of matrix metalloproteinases MMP-1, MMP-9 and interleukin-1beta. High glucose also enhances interferon gamma-induced priming effect on lipopolysaccharide-stimulated MMP-1 secretion. High glucose and interferon gamma exert the synergistic effect on MMP-1 expression by enhancing STAT1 phosphorylation and STAT1 transcriptional activity |
695964 |
3.4.24.81 | ADAM10 endopeptidase |
U-937 cell |
- |
720160 |
3.4.24.86 | ADAM 17 endopeptidase |
U-937 cell |
- |
708699 |
3.4.25.1 | proteasome endopeptidase complex |
U-937 cell |
- |
712918 |
3.5.1.98 | histone deacetylase |
U-937 cell |
- |
696616 |
3.5.3.15 | protein-arginine deiminase |
U-937 cell |
- |
711811 |
3.5.4.4 | adenosine deaminase |
U-937 cell |
- |
712672 |
3.6.5.5 | dynamin GTPase |
U-937 cell |
- |
700294 |
4.1.1.17 | ornithine decarboxylase |
U-937 cell |
- |
699928 |
4.1.1.28 | aromatic-L-amino-acid decarboxylase |
U-937 cell |
- |
705269 |
4.2.1.11 | phosphopyruvate hydratase |
U-937 cell |
- |
702856 |