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Literature summary for 2.7.1.107 extracted from

  • Yamada, K.; Sakane, F.; Imai, S.; Tsushima, S.; Murakami, T.; Kanoh, H.
    Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells (2003), Biochem. Biophys. Res. Commun., 305, 101-107.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm prior to cell attachment, phorbol ester induce translocation of DGKgamma from the cytoplasm to the cell periphery Homo sapiens 5737
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extracellular prior to cell attachment, phorbol ester induce translocation of DGKgamma from the cytoplasm to the cell periphery Homo sapiens
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1,2-diacyl-sn-glycerol Homo sapiens DGKgamma negatively regulates macrophage differentiation through its catalytic action operating on the cytoskeleton ADP + 1,2-diacyl-sn-glycerol 3-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens
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DGKgamma
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Source Tissue

Source Tissue Comment Organism Textmining
granulocyte enzyme expression remains almost unchanged in granulocytic differentiation pathway Homo sapiens
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granulocyte enzyme expression remained almost unchanged in granulocytic differentiation pathway Homo sapiens
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HL-60 cell level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages Homo sapiens
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HL-60 cell levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages Homo sapiens
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U-937 cell levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages Homo sapiens
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U937 cell level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1,2-diacyl-sn-glycerol DGKgamma negatively regulates macrophage differentiation through its catalytic action operating on the cytoskeleton Homo sapiens ADP + 1,2-diacyl-sn-glycerol 3-phosphate
-
?

Synonyms

Synonyms Comment Organism
DGKgamma
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Homo sapiens