Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | prior to cell attachment, phorbol ester induce translocation of DGKgamma from the cytoplasm to the cell periphery | Homo sapiens | 5737 | - |
extracellular | prior to cell attachment, phorbol ester induce translocation of DGKgamma from the cytoplasm to the cell periphery | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-diacyl-sn-glycerol | Homo sapiens | DGKgamma negatively regulates macrophage differentiation through its catalytic action operating on the cytoskeleton | ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | - |
DGKgamma | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
granulocyte | enzyme expression remains almost unchanged in granulocytic differentiation pathway | Homo sapiens | - |
granulocyte | enzyme expression remained almost unchanged in granulocytic differentiation pathway | Homo sapiens | - |
HL-60 cell | level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages | Homo sapiens | - |
HL-60 cell | levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages | Homo sapiens | - |
U-937 cell | levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages | Homo sapiens | - |
U937 cell | level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-diacyl-sn-glycerol | DGKgamma negatively regulates macrophage differentiation through its catalytic action operating on the cytoskeleton | Homo sapiens | ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DGKgamma | - |
Homo sapiens |