Application | Comment | Organism |
---|---|---|
medicine | the enzyme may have important implications in the pathophysiology and treatment of thrombotic disorders | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0015 | - |
fibrinogen | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme may have important implications in the pathophysiology and treatment of thrombotic disorders | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
U-937 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fibrin + H2O | - |
Homo sapiens | ? | - |
? | |
fibrinogen + H2O | cleaves the alpha-chain, the beta-chain and the gamma-chain | Homo sapiens | low molecular weight fragments of fibrinogen | - |
? | |
additional information | the enzyme may have important implications in the pathophysiology and treatment of thrombotic disorders | Homo sapiens | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0014 | - |
fibrinogen | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
3.5 | - |
fibrinogen | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
3.5 | 5 | pH 3.5: maximal activity, pH 5.0: about 50% of maximal activity, fibrinogen as substrate | Homo sapiens |