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BRENDA support

Information on EC 3.4.21.37 - leukocyte elastase

for references in articles please use BRENDA:EC3.4.21.37

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IUBMB Comments

Differs from pancreatic elastase in specificity on synthetic substrates and in inhibitor sensitivity. In peptidase family S1 (trypsin family). Formerly included in EC 3.4.21.11

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Hydrolysis of proteins, including elastin. Preferential cleavage Val-/- > Ala-/-

Synonyms
neutrophil elastase, leukocyte elastase, granulocyte elastase, pmn elastase, elane, pmn-elastase, polymorphonuclear leukocyte elastase, polymorphonuclear neutrophil elastase, neutrophil-elastase, lysosomal elastase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Hydrolysis of proteins, including elastin. Preferential cleavage Val-/- > Ala-/-
show the reaction diagram
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