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2 CMP-N-acetyl-beta-neuraminate + 2 methyl beta-D-(3-O-sulfo)Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal
2 CMP + methyl alpha-Neu5Ac-(2->2)-beta-D-(3-O-sulfo)Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal + methyl alpha-Neu5Ac-(2->4)-beta-D-(3-O-sulfo)Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal
-
-
-
-
?
asialo-alpha1 acid glycoprotein
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + 2-azidoethyl beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + 2-azidoethyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
CMP-N-acetyl-beta-neuraminate + 3-O-[beta-D-Gal-(1->3)-beta-D-GalNAc]-N-acetyl-L-threonine methyl ester
CMP + 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc]-N-acetyl-L-threonine methyl ester
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP-N-acetyl-beta-neuraminate + agalactofetuin
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + allyl beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + allyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
24.1% of the activity compared to allylbeta-D-Gal-(1->4)-beta-D-GlcNAc, alpha2,3(N) sialyltransferase. 112% of the activity compared to benzyl beta-D-(3-O-Me)Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc, alpha2,3(O) sialyltransferase
-
-
?
CMP-N-acetyl-beta-neuraminate + allyl beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP + allyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc
-
123.1% of the activity compared to allylbeta-D-Gal-(1->4)-beta-D-GlcNAc, alpha2,3(N) sialyltransferase. 42.1% of the activity compared to benzyl beta-D-(3-O-Me)Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc, alpha2,3(O) sialyltransferase
-
-
?
CMP-N-acetyl-beta-neuraminate + antifreeze protein
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + asialofetuin
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + asialofetuin
CMP + ?
-
-
-
?
CMP-N-acetyl-beta-neuraminate + asialotransferrin
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + benzyl beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + benzyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-(2-O-Me)Gal-(1->3)-beta-D-GlcNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-(2-O-Me)Gal-(1->3)-beta-D-GlcNAc
-
115.3% of the activity compared to allylbeta-D-Gal-(1->4)-beta-D-GlcNAc, alpha2,3(N) sialyltransferase. 2.9% of the activity compared to benzyl beta-D-(3-O-Me)Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc, alpha2,3(O) sialyltransferase
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
100% activity
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-beta-D-galactosyl-(1->3)-beta-D-glucosyl-(1->4)-R
?
-
2.9% activity compared to beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R
CMP + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
1% activity compared to beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-Gal-(1->4)-beta-GlcNAc-R
CMP + alphaNeuAc-(2->3)-beta-Gal-(1->4)-beta-GlcNAc-R
ST3Gal IV overexpressed in the gastric MKN45 cell line, shows exclusive enzymatic activity towards glycoproteins containing terminal beta-Gal-(1->4)-beta-GlcNAc structure
-
-
?
CMP-N-acetyl-beta-neuraminate + Galbeta(1->3)(GlcNAcbeta(1->6))GalNAc-OBn
CMP + ?
-
-
-
?
CMP-N-acetyl-beta-neuraminate + Galbeta(1->3)GalNAc-OBn
CMP + Neu5Acalpha(2->3)Galbeta(1->3)GalNAc-OBn
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
CMP + ganglioside GM1b
CMP-N-acetyl-beta-neuraminate + ganglioside Gb5
CMP + ganglioside MSGb5
i.e. beta-D-Gal-(1_>3)-beta-D-GalNAc-(1-3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1a
?
-
very low activity
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1a
CMP + ?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
CMP-N-acetyl-beta-neuraminate + ganglioside GL-2a
CMP + ganglioside GM3
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1
CMP + ganglioside GD1
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
CMP-N-acetyl-beta-neuraminate + ganglioside GM2
?
-
very low activity
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM3
CMP + ganglioside GD3
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + gangloside asialo-GM1
CMP + ganglioside GM1b
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + methyl beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal
CMP + methyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal
-
106.8% of the activity compared to allylbeta-D-Gal-(1->4)-beta-D-GlcNAc, alpha2,3(N) sialyltransferase. 120.8% of the activity compared to benzyl beta-D-(3-O-Me)Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc, alpha2,3(O) sialyltransferase
-
-
?
CMP-N-acetyl-beta-neuraminate + porcine submaxillary asialo-mucin
?
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + [asialofetuin]-(O-3-(beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-serine
CMP + [protein]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-serine
CMP-N-acetyl-beta-neuraminate + [asialofetuin]-(O-3-(beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-threonine
CMP + [protein]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-threonine
CMP-N-acetylneuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc-R
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-R
broad substrate specificity, the viral enzyme utilizes disaccharides type I-III and also fucosylated Lewis a and Lewis x
-
-
?
additional information
?
-
CMP-N-acetyl-beta-neuraminate + 2-azidoethyl beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + 2-azidoethyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + 2-azidoethyl beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + 2-azidoethyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + 3-O-[beta-D-Gal-(1->3)-beta-D-GalNAc]-N-acetyl-L-threonine methyl ester
CMP + 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc]-N-acetyl-L-threonine methyl ester
-
-
-
?
CMP-N-acetyl-beta-neuraminate + 3-O-[beta-D-Gal-(1->3)-beta-D-GalNAc]-N-acetyl-L-threonine methyl ester
CMP + 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc]-N-acetyl-L-threonine methyl ester
-
-
-
?
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
-
-
?
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
-
-
?
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
-
-
?
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
relative Vmax for ST3Gal IV is 2:5:1 for beta-D-Gal-(1->3)-beta-D-GlcNAc, beta-D-Gal-(1->4)-beta-D-GlcNAc and beta-D-Gal-(1->3)-beta-D-GalNAc, respectively
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
relative Vmax is 4:2:1 for beta-D-Gal-(1->3)-beta-D-GlcNAc, beta-D-Gal-(1->4)-beta-D-GlcNAc and beta-D-Gal-(1->3)-beta-D-GalNAc, respectively
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
Vmax is 10fold higher with beta-D-Gal-(1->3)-beta-D-GalNAc than with beta-D-Gal-(1->3)-beta-D-GlcNAc as substrate
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
Vmax is 4fold higher with beta-D-Gal-(1->3)-beta-D-GalNAc than with beta-D-Gal-(1->3)-beta-D-GlcNAc as substrate
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc
-
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc
relative Vmax for ST3Gal IV is 2:5:1 for beta-D-Gal-(1->3)-beta-D-GlcNAc, beta-D-Gal-(1->4)-beta-D-GlcNAc and beta-D-Gal-(1->3)-beta-D-GalNAc, respectively
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc
Vmax is 10fold higher with beta-D-Gal-(1->3)-beta-D-GalNAc than with beta-D-Gal-(1->3)-beta-D-GlcNAc as substrate
-
-
?
CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GlcNAc
CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc
Vmax is 4fold higher with beta-D-Gal-(1->3)-beta-D-GalNAc than with beta-D-Gal-(1->3)-beta-D-GlcNAc as substrate
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
CMP + ganglioside GM1b
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
CMP + ganglioside GM1b
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
CMP + ganglioside GM1b
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
CMP + ganglioside GM1b
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GA1
CMP + ganglioside GM1b
-
sialylated at 61% the rate of GM1
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
-
sialylated at 120% the rate of GM1
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
CMP + ganglioside GT1b
pyridylaminated ganglioside
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
ganglioside GM1a labeled with boron dipyrromethene difluoride
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
ganglioside GM1a labeled with boron dipyrromethene difluoride
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
ganglioside GM1a is galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide, most active acceptor
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
i.e. ganglioside GD1a
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
-
-
-
?
CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
CMP + ganglioside GD1a
pyridylaminated ganglioside
-
-
?
CMP-N-acetyl-beta-neuraminate + [asialofetuin]-(O-3-(beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-serine
CMP + [protein]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-serine
-
-
-
?
CMP-N-acetyl-beta-neuraminate + [asialofetuin]-(O-3-(beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-serine
CMP + [protein]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-serine
-
-
-
?
CMP-N-acetyl-beta-neuraminate + [asialofetuin]-(O-3-(beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-threonine
CMP + [protein]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-threonine
-
-
-
?
CMP-N-acetyl-beta-neuraminate + [asialofetuin]-(O-3-(beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-threonine
CMP + [protein]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->)))-L-threonine
-
-
-
?
additional information
?
-
no transfer onto D-Gal-beta-(1->4)-D-GlcNAc, GalNAc-beta-(1->4)-D-GlcNAc or D-Gal-beta-(l->4)-D-Glc is detected
-
-
?
additional information
?
-
-
no transfer onto D-Gal-beta-(1->4)-D-GlcNAc, GalNAc-beta-(1->4)-D-GlcNAc or D-Gal-beta-(l->4)-D-Glc is detected
-
-
?
additional information
?
-
no transfer onto Galbeta-(1->4)-D-GlcNAc, GalNAc-beta-(1->4)-D-GlcNAc or Gal-beta-(1->4)-Glc is detected
-
-
?
additional information
?
-
-
no transfer onto Galbeta-(1->4)-D-GlcNAc, GalNAc-beta-(1->4)-D-GlcNAc or Gal-beta-(1->4)-Glc is detected
-
-
?
additional information
?
-
MeO-3-Galbeta(1->3)GalNAc-OBn is a poor acceptor for the enzyme
-
-
-
additional information
?
-
MeO-3-Galbeta(1->3)GalNAc-OBn is a poor acceptor for the enzyme
-
-
-
additional information
?
-
-
MeO-3-Galbeta(1->3)GalNAc-OBn is a poor acceptor for the enzyme
-
-
-
additional information
?
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acceptor preference of ST3GalA.1 is different from that of ST3GalA.2, although their acceptor substrate specificities are the same; i.e., gangliosides serve as predominant acceptors for the latter over O-glycosidically linked oligosaccharides of glycoproteins, which are much better acceptors for the former
-
-
?
additional information
?
-
acceptor preference of ST3GalA.1 is different from that of ST3GalA.2, although their acceptor substrate specificities are the same; i.e., gangliosides serve as predominant acceptors for the latter over O-glycosidically linked oligosaccharides of glycoproteins, which are much better acceptors for the former
-
-
?
additional information
?
-
-
acceptor preference of ST3GalA.1 is different from that of ST3GalA.2, although their acceptor substrate specificities are the same; i.e., gangliosides serve as predominant acceptors for the latter over O-glycosidically linked oligosaccharides of glycoproteins, which are much better acceptors for the former
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-
?
additional information
?
-
-
the enzyme does not catabolizes urea transporter UT-A3 alpha2,6-sialylation
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?
additional information
?
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-
no activity with beta-D-galactosyl-(1->6)-N-acetyl-beta-D-galactosaminyl-R, beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosyl-R, beta-D-galactosyl-(1->6)-N-acetyl-beta-D-glucosyl-R, beta-D-galactosyl-(1->4)beta-D-glucosyl-R, beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-beta-D-galactosyl-(1->3)-beta-D-glucosyl-(1->4)-R, D-galactose, and methyl-beta-D-galactopyranoside. Ganglioside GL-4, lactosyl ceramide do not serve as acceptors
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A systematic analysis of acceptor specificity and reaction kinetics of five human alpha(2,3)sialyltransferases Product inhibition studies illustrate reaction mechanism for ST3Gal-I
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Homo sapiens (Q11206), Homo sapiens (Q16842), Homo sapiens
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TNF induces the expression of the sialyltransferase ST3Gal IV in human bronchial mucosa via MSK1/2 protein kinases and increases FliD/sialyl-Lewis(X)-mediated adhesion of Pseudomonas aeruginosa
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Kinetic properties and acceptor substrate preferences of two kinds of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase from mouse brain
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33
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Mus musculus (P54751), Mus musculus (Q11204), Mus musculus
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Chandrasekaran, E.V.; Xue, J.; Xia, J.; Chawda, R.; Piskorz, C.; Locke, R.D.; Neelamegham, S.; Matta, K.L.
Analysis of the specificity of sialyltransferases toward mucin core 2, globo, and related structures. Identification of the sialylation sequence and the effects of sulfate, fucose, methyl, and fluoro substituents of the carbohydrate chain in the biosynthesis of selectin and siglec ligands, and novel sialylation by cloned alpha2,3(O)sialyltransferase
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44
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Delineation of the minimal catalytic domain of human Galbeta1-3GalNAc alpha2,3-sialyltransferase (hST3Gal I)
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Molecular cloning and expression of Galbeta1,3GalNAcalpha2,3-sialyltransferase from mouse brain
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Cloning and expression of cDNA for a human Gal(beta1-3)GalNAc alpha2,3-sialyltransferase from the CEM T-cell line
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A novel viral alpha2,3-sialyltransferase (v-ST3Gal I) transfer of sialic acid to fucosylated acceptors
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The evolution of galactose alpha2,3-sialyltransferase Ciona intestinalis ST3GAL I/II and Takifugu rubripes ST3GAL II sialylate Galbeta1,3GalNAc structures on glycoproteins but not glycolipids
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21
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A novel monosialoganglioside synthesized by a rat brain cytidine-5'-monophospho-N-acetylneuraminic acid galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide sialyltransferase
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1973
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Yip, M.; Nguyen, N.
The enzymic synthesis of GM1b rat-brain CMP-N-acetylneuraminic acid sialo-GM1 sialyltransferase
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16
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Rattus norvegicus
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