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Information on EC 3.1.1.25 - 1,4-lactonase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.25 1,4-lactonase
IUBMB Comments
The enzyme is specific for 1,4-lactones with 4-8 carbon atoms. It does not hydrolyse simple aliphatic esters, acetylcholine, sugar lactones or substituted aliphatic lactones, e.g. 3-hydroxy-4-butyrolactone; requires Ca2+.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
AHL lactonase, AiiA, gamma-lactonase, lactonase, lactonase, gamma, levo-lactonase, Saci_2140, SacPox, SisLac, SSO2522, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 1,4-lactone + H2O = a 4-hydroxyacid
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