EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
4.1.99.13 | (6-4)DNA photolyase |
heart |
- |
747608 |
2.3.2.24 | (E3-independent) E2 ubiquitin-conjugating enzyme |
heart |
- |
759177 |
1.1.1.75 | (R)-aminopropanol dehydrogenase |
heart |
- |
287301 |
1.1.5.13 | (S)-2-hydroxyglutarate dehydrogenase |
heart |
- |
755232 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
heart |
- |
486345, 671597, 705206, 756108 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
heart |
analysis of enzyme mRNA expression, transcript of approximately 2 kb length dominant |
487202 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
heart |
low expression level |
-, 705005 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
heart |
mAGPAT1, mAGPAT2, mAGPAT3, mAGPAT4 barely detectable, mAGPAT5 expressed at high levels, mRNA expression of cardiac mAGPAT3 is regulated by activation of peroxisome-proliferator-activated receptors |
657854 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
heart |
- |
486618, 486622, 486626, 486629, 486631, 657761 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
heart |
low content |
755989 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
heart |
myocardium |
486625 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
heart |
northern blot analysis |
688774 |
2.7.8.22 | 1-alkenyl-2-acylglycerol choline phosphotransferase |
heart |
- |
643767 |
2.3.1.121 | 1-alkenylglycerophosphoethanolamine O-acyltransferase |
heart |
- |
486241 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
heart |
- |
682621, 80941 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
heart |
- |
641769 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
heart |
high expression of PIP5KIbeta and PIP5KIalpha |
641842 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
heart |
high mRNA expression |
684375 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
heart |
PIP4Kgamma in heart run predominantly as a 40 kDa band, suggesting that processing of this isoform occurs. |
684375 |
1.5.1.1 | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] |
heart |
- |
392038 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
heart |
26% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
heart |
low mRNA expression |
692939 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
heart |
the 3 kb isoform is the most abundant one |
692332 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
heart |
- |
760868 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
heart |
coexpression of 121beta-HSD1 with hexose-6-phosphate dehydrogenase |
686419 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
heart |
low level of expression, low activity |
693886 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
heart |
of normotensive and hypertensive rats, the latter are hyperthrophied and fibrotic and have structural alterations in the coronary circulation, expression of isozymes 11beta-HSD1 and 11beta-HSD2, overview |
670034 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
heart |
weak expression |
693886 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
heart |
of normotensive and hypertensive rats, the latter are hyperthrophied and fibrotic and have structural alterations in the coronary circulation, expression of isozymes 11beta-HSD1 and 11beta-HSD2, overview |
670034 |
1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
heart |
- |
390820, 390826 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
heart |
- |
285912, 285918 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
heart |
- |
734569 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
heart |
- |
688956, 740849 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
heart |
low mRNA expression |
688007 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
heart |
moderate expression |
685803 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
heart |
very low expression of isozymes AKR1B15.1 and AKR1B15.2 |
740743 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
heart |
- |
135422, 750212, 751698 |
2.7.1.76 | 2'-deoxyadenosine kinase |
heart |
low activity |
641099 |
2.7.1.160 | 2'-phosphotransferase |
heart |
- |
690027 |
2.7.1.160 | 2'-phosphotransferase |
heart |
high level of TRPT1 transcript |
668216 |
1.3.1.34 | 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing] |
heart |
- |
652365 |
1.3.1.124 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] |
heart |
- |
-, 390714, 700872, 759138 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
heart |
- |
705006 |
2.3.1.62 | 2-acylglycerophosphocholine O-acyltransferase |
heart |
- |
487355 |
2.6.1.39 | 2-aminoadipate transaminase |
heart |
- |
639985 |
1.3.1.27 | 2-hexadecenal reductase |
heart |
- |
390629 |
2.2.1.5 | 2-hydroxy-3-oxoadipate synthase |
heart |
- |
395924, 395928, 395929, 657709 |
2.2.1.5 | 2-hydroxy-3-oxoadipate synthase |
heart |
distribution in rat tissues |
395928 |
3.1.3.106 | 2-lysophosphatidate phosphatase |
heart |
presence of lipin-1 and lipin-3, lipin-2 is absent. Marked differences in cardiac distribution of PAP1 |
707381 |
1.2.1.49 | 2-oxoaldehyde dehydrogenase (NADP+) |
heart |
- |
288148 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
heart |
- |
348910, 348914, 349005, 349014, 349020, 349021, 349023, 349026, 349027, 349028, 349033, 656580, 656591, 672280, 676088, 676319, 685238, 758747, 759437, 759561 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
heart |
overall reaction activities of the PDH and OGDH complexes are very high, in order of heart > abdominal skeletal muscle > kidney. Their gene expression is strongest in heart and skeletal muscle |
759549 |
2.1.1.222 | 2-polyprenyl-6-hydroxyphenol methylase |
heart |
- |
485141 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
heart |
moderate expression rate of AKR1C23 |
669908 |
2.1.1.166 | 23S rRNA (uridine2552-2'-O)-methyltransferase |
heart |
transcripts are abundant |
703879 |
3.1.3.7 | 3'(2'),5'-bisphosphate nucleotidase |
heart |
- |
728931 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
heart |
- |
135264, 684819, 684821, 687488, 689817, 694262, 716347 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
heart |
highest expression in testis, followed by eye, liver, skeletal muscle, heart, 7-day embryo, kidney, ovary, and brain in decreasing order |
689816 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
heart |
lowest expression in heart |
691716 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
heart |
neonatal cardiac myocyte |
730102 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
heart |
PDE7A2 |
689817 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
heart |
- |
649549, 650342, 651412, 716347 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
heart |
enzyme isoform PDE5 mRNA and protein are markedly upregulated in hypertrophied human right ventricle |
679253 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
heart |
enzyme isoform PDE5 mRNA and protein are markedly upregulated in hypertrophied right ventricle |
679253 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
heart |
low gene expression |
691533 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
heart |
whole myocardium from failing hearts have 50% lower PDE5A expression and 30% less total and EMD82639-inhibitable cGMP-PDE activity |
651222 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
heart |
- |
135228, 135236, 135264, 135266, 135274, 692697, 716347, 752065 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
heart |
10-20% of activity found in brain |
651468 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
heart |
fetal and adult |
135271 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
heart |
PDE1 |
668987 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
heart |
PDE11A4, weak antibody staining of neuronal cells within parasympathetic ganglia in the heart |
668988 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
heart |
PDE2 |
668987 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
heart |
in female hamsters |
740637 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
heart |
isozyme 17beta-HSD8 |
675476 |
1.1.1.102 | 3-dehydrosphinganine reductase |
heart |
high expression |
656256 |
1.1.1.102 | 3-dehydrosphinganine reductase |
heart |
low level of expression |
656256 |
1.14.99.60 | 3-demethoxyubiquinol 3-hydroxylase |
heart |
COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney |
746956 |
2.1.1.64 | 3-demethylubiquinol 3-O-methyltransferase |
heart |
- |
485141 |
1.1.1.35 | 3-hydroxyacyl-CoA dehydrogenase |
heart |
- |
286269, 286588, 286596, 286598, 286606, 286607, 286608, 286609, 286610, 286611, 33713, 673340, 673530, 723558 |
1.1.1.30 | 3-hydroxybutyrate dehydrogenase |
heart |
- |
286512, 286513, 286514, 286516, 286517, 286519, 286520, 286521, 286525, 286528, 286530, 286535, 286536, 286538, 286540, 286542 |
1.1.1.31 | 3-hydroxyisobutyrate dehydrogenase |
heart |
- |
286549, 722472 |
3.1.2.4 | 3-hydroxyisobutyryl-CoA hydrolase |
heart |
- |
653127, 94556, 94558 |
1.1.1.59 | 3-hydroxypropionate dehydrogenase |
heart |
- |
287142 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
heart |
- |
645557, 645561, 645562 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
heart |
- |
349060, 349070, 349074, 712648, 763049, 94884 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
heart |
lowest activity |
675563 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
heart |
only a minor proportion of branched-chain 2-oxoacid dehydrogenase complex is active in mitochondria freshly prepared from rat heart |
349077 |
2.8.3.5 | 3-oxoacid CoA-transferase |
heart |
- |
645967, 645968, 645969, 645970, 645971, 645974, 645975, 645978, 645979, 645984, 645986, 645987, 645988, 645989, 645990, 645994, 645995, 672216, 690880, 705523, 723826, 724277, 737420 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
heart |
in female hamsters |
740637 |
1.1.1.53 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase |
heart |
- |
688455, 698084 |
1.1.1.53 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase |
heart |
weak expression of subunit A, weak expression of subunit B |
762606 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
heart |
- |
389547 |
1.7.1.11 | 4-(dimethylamino)phenylazoxybenzene reductase |
heart |
- |
394432 |
2.5.1.39 | 4-hydroxybenzoate polyprenyltransferase |
heart |
- |
636998 |
2.5.1.39 | 4-hydroxybenzoate polyprenyltransferase |
heart |
high enzyme expression |
657846 |
1.2.1.47 | 4-trimethylammoniobutyraldehyde dehydrogenase |
heart |
- |
671302, 690142, 743576, 762831 |
1.2.1.47 | 4-trimethylammoniobutyraldehyde dehydrogenase |
heart |
enzyme TMABA-DH colocalizes with myosin light chains in cardiac myocytes |
743576 |
1.2.1.47 | 4-trimethylammoniobutyraldehyde dehydrogenase |
heart |
low activity |
671302 |
1.2.1.47 | 4-trimethylammoniobutyraldehyde dehydrogenase |
heart |
medium activity |
671302 |
3.6.1.62 | 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase |
heart |
- |
716218 |