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Literature summary for 2.3.1.62 extracted from
- Acylation of 2-acyl-glycerophosphocholine in guinea pig heart microsomal fractions (1989), Biochem. J., 261, 575-580.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5'-dithiobis-(2-nitrobenzoic acid) | 0.5 mM 76% activity | Cavia porcellus |  |
| dithiothreitol | 0.5 mM 47% activity | Cavia porcellus | |
| additional information | not inhibited by glutathione or iodoacetate | Cavia porcellus | |
| N-ethylmaleimide | 0.5 mM 68% activity | Cavia porcellus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Cavia porcellus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | enhanced activity by 75% | Cavia porcellus | |
| additional information | Ca2+ does not affect activity | Cavia porcellus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine | Cavia porcellus | reaction in phosphatidylcholine metabolism | CoA + phosphatidylcholine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Cavia porcellus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + phosphatidylcholine | - |
? | |
| acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine | reaction in phosphatidylcholine metabolism | Cavia porcellus | CoA + phosphatidylcholine | - |
? | |
| arachidonoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-arachidonoyl-2-arachidonoyl-sn-glycero-3-phosphocholine | - |
? | |
| arachidonoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-arachidonoyl-2-palmitoyl-sn-glycero-3-phosphocholine | - |
? | |
| linoleoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-linoleoyl-2-arachidonoyl-sn-glycero-3-phosphocholine | - |
? | |
| linoleoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-linoleoyl-2-palmitoyl-sn-glycero-3-phosphocholine | - |
? | |
| oleoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphocholine | - |
? | |
| oleoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine | - |
? | |
| palmitoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine | - |
? | |
| palmitoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine | - |
? | |
| stearoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine | - |
? | |
| stearoyl-CoA + 2-palmitoyl-sn-glycero-3-phosphocholine | - |
Cavia porcellus | CoA + 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 2-acylglycerophosphocholine acyltransferase | - |
Cavia porcellus |
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