EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
3.2.2.16 | methylthioadenosine nucleosidase |
cell surface |
Bgp protein |
GO:0009986 AmiGO QuickGO |
698517 |
3.2.2.5 | NAD+ glycohydrolase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
668457 |
3.2.2.5 | NAD+ glycohydrolase |
cell surface |
NADase is a glycosylated, glycosylphosphatidylinositol-anchored cell surface protein |
GO:0009986 AmiGO QuickGO |
-, 732135 |
3.2.2.9 | adenosylhomocysteine nucleosidase |
cell surface |
Bgp protein |
GO:0009986 AmiGO QuickGO |
698517 |
3.4.11.16 | Xaa-Trp aminopeptidase |
cell surface |
cells expressing the enzyme intracellularly do not necessarily express it at the surface |
GO:0009986 AmiGO QuickGO |
643873 |
3.4.11.2 | membrane alanyl aminopeptidase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
663873, 664466, 665146, 665231, 665710, 665955, 665958, 666240, 666997, 666998, 707961, 707970 |
3.4.11.2 | membrane alanyl aminopeptidase |
cell surface |
CD13 |
GO:0009986 AmiGO QuickGO |
665112 |
3.4.11.2 | membrane alanyl aminopeptidase |
cell surface |
ectoenzyme |
GO:0009986 AmiGO QuickGO |
664688, 666148 |
3.4.11.2 | membrane alanyl aminopeptidase |
cell surface |
ectoenzyme, the enzyme has an N-terminal membrane anchor |
GO:0009986 AmiGO QuickGO |
663607 |
3.4.11.2 | membrane alanyl aminopeptidase |
cell surface |
ectopeptidase |
GO:0009986 AmiGO QuickGO |
663842 |
3.4.11.2 | membrane alanyl aminopeptidase |
cell surface |
wild-type mature enzyme |
GO:0009986 AmiGO QuickGO |
665708 |
3.4.11.3 | cystinyl aminopeptidase |
cell surface |
the enzyme translocates to the cell surface within GLUT4 vesicles in response to insulin |
GO:0009986 AmiGO QuickGO |
668760 |
3.4.11.3 | cystinyl aminopeptidase |
cell surface |
TUG regulates IRAP cell surface targeting in 3T3-L1 adipocytes |
GO:0009986 AmiGO QuickGO |
-, 754109 |
3.4.11.7 | glutamyl aminopeptidase |
cell surface |
enzyme resides in the cytosol, but a subset of molecules are both bound to and secreted from the cell surface |
GO:0009986 AmiGO QuickGO |
-, 732596 |
3.4.11.7 | glutamyl aminopeptidase |
cell surface |
of COS cells, wild-type enzyme and mutant enzyme C43S |
GO:0009986 AmiGO QuickGO |
654495 |
3.4.14.12 | Xaa-Xaa-Pro tripeptidyl-peptidase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
647188 |
3.4.14.5 | dipeptidyl-peptidase IV |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
679975, 703039, 703300, 703678, 704968 |
3.4.15.1 | peptidyl-dipeptidase A |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
667172 |
3.4.15.1 | peptidyl-dipeptidase A |
cell surface |
both isoforms are shed from the cell surface via a sheddase-mediated cleavage, testis ACE is shed much more efficiently than somatic ACE |
GO:0009986 AmiGO QuickGO |
678511 |
3.4.15.1 | peptidyl-dipeptidase A |
cell surface |
membrane-bound on the surface of epithelial cells of epididymis and prostate |
GO:0009986 AmiGO QuickGO |
755108 |
3.4.16.4 | serine-type D-Ala-D-Ala carboxypeptidase |
cell surface |
PBP3 is evenly distributed on both hemispheres but absent at the equator, the site of future division |
GO:0009986 AmiGO QuickGO |
670303 |
3.4.16.5 | carboxypeptidase C |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
702764 |
3.4.17.12 | carboxypeptidase M |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
668817, 669830, 670291 |
3.4.17.21 | Glutamate carboxypeptidase II |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
668154, 669506, 708256 |
3.4.17.21 | Glutamate carboxypeptidase II |
cell surface |
of glia and nonmyelinating Schwann cells |
GO:0009986 AmiGO QuickGO |
707124 |
3.4.17.21 | Glutamate carboxypeptidase II |
cell surface |
PSMA is a transmembrane protein commonly found on the surface of late-stage and metastatic prostate cancer |
GO:0009986 AmiGO QuickGO |
709648 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
707074 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cell surface |
cell-surface non-raft protein with the extracellular N-terminal and intracellular C-terminal domains. Binding to SARS-CoV-2 protein S induces the ACE2 internalization |
GO:0009986 AmiGO QuickGO |
762787 |
3.4.18.1 | cathepsin X |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
679023 |
3.4.18.1 | cathepsin X |
cell surface |
cathepsin X is localized on the cell surface of primary osteoblasts |
GO:0009986 AmiGO QuickGO |
708633 |
3.4.19.13 | glutathione gamma-glutamate hydrolase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
754112 |
3.4.21.105 | rhomboid protease |
cell surface |
PbROM1 localizes to the surface of sporozoites after salivary gland invasion |
GO:0009986 AmiGO QuickGO |
710398 |
3.4.21.105 | rhomboid protease |
cell surface |
TgROM4 is localized to the cell surface |
GO:0009986 AmiGO QuickGO |
-, 660387 |
3.4.21.105 | rhomboid protease |
cell surface |
TgROM5 is localized to the cell surface, primarily at the posterior of the parasite |
GO:0009986 AmiGO QuickGO |
-, 660387 |
3.4.21.106 | hepsin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
650510, 687522 |
3.4.21.107 | peptidase Do |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
669100 |
3.4.21.109 | matriptase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
657796, 673572, 675024, 683145, 683364, 683489, 683493, 683494, 683514, 683674, 731663 |
3.4.21.109 | matriptase |
cell surface |
acid-induced matriptase activation takes place both on the cell surface and inside the cells, likely due to the parallel intracellular acidification that activates intracellular matriptase |
GO:0009986 AmiGO QuickGO |
709136 |
3.4.21.109 | matriptase |
cell surface |
apical surface of epithelial cells |
GO:0009986 AmiGO QuickGO |
732419 |
3.4.21.109 | matriptase |
cell surface |
cell surface type II transmembrane protein |
GO:0009986 AmiGO QuickGO |
731410 |
3.4.21.109 | matriptase |
cell surface |
matriptase is activated when it reaches the cell surface |
GO:0009986 AmiGO QuickGO |
708947 |
3.4.21.109 | matriptase |
cell surface |
matriptase translocates to the cell surface and is activated within min after exposure of breast cancer cells to sphingosine-1-phosphate requiring actin cytoskeleton remodeling |
GO:0009986 AmiGO QuickGO |
683893 |
3.4.21.109 | matriptase |
cell surface |
the catalytic domain of matriptase is located in the extracellular space |
GO:0009986 AmiGO QuickGO |
683343 |
3.4.21.109 | matriptase |
cell surface |
the cytoplasmic domain of the enzyme contains an endocytosis motif that mediates the internalization of cell surface enzyme in a dynamin-dependent manner, Iron depletion does not affect the internalization of cell surface enzyme |
GO:0009986 AmiGO QuickGO |
732181 |
3.4.21.110 | C5a peptidase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
651482, 673973 |
3.4.21.122 | transmembrane protease serine 2 |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
754529 |
3.4.21.20 | cathepsin G |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
718143, 753787 |
3.4.21.20 | cathepsin G |
cell surface |
active enzyme |
GO:0009986 AmiGO QuickGO |
683193 |
3.4.21.20 | cathepsin G |
cell surface |
expression at high levels on the surface of activated human neutrophils in catalytically active but inhibitor-resistant form |
GO:0009986 AmiGO QuickGO |
683644 |
3.4.21.34 | plasma kallikrein |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
667855 |
3.4.21.37 | leukocyte elastase |
cell surface |
of activated neutrophils |
GO:0009986 AmiGO QuickGO |
683644 |
3.4.21.37 | leukocyte elastase |
cell surface |
of neutrophils |
GO:0009986 AmiGO QuickGO |
683316 |
3.4.21.38 | coagulation factor XIIa |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
696541 |
3.4.21.43 | classical-complement-pathway C3/C5 convertase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
732705, 81409 |
3.4.21.47 | alternative-complement-pathway C3/C5 convertase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
732705, 753082, 753422 |
3.4.21.5 | thrombin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
683292, 684005 |
3.4.21.50 | lysyl endopeptidase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
-, 732885 |
3.4.21.50 | lysyl endopeptidase |
cell surface |
the enzyme is secreted by the type IX secretion system, T9SS, and anchored onto the cell surface by binding to A-LPS |
GO:0009986 AmiGO QuickGO |
731826 |
3.4.21.59 | Tryptase |
cell surface |
of degranulated mast cells |
GO:0009986 AmiGO QuickGO |
670795 |
3.4.21.6 | coagulation factor Xa |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
652731, 683259, 717234, 717253 |
3.4.21.62 | Subtilisin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
-, 707888 |
3.4.21.68 | t-Plasminogen activator |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
701276 |
3.4.21.69 | Protein C (activated) |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
717424 |
3.4.21.69 | Protein C (activated) |
cell surface |
inactive enzyme |
GO:0009986 AmiGO QuickGO |
731565 |
3.4.21.69 | Protein C (activated) |
cell surface |
the activated protein C occurs at the cell surfaceof endothelial cells |
GO:0009986 AmiGO QuickGO |
683624 |
3.4.21.7 | plasmin |
cell surface |
plasminogen is a major surface-bound protein |
GO:0009986 AmiGO QuickGO |
718277 |
3.4.21.72 | IgA-specific serine endopeptidase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
666398, 666834 |
3.4.21.73 | u-Plasminogen activator |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
708679, 709067, 709091, 709570, 710553 |
3.4.21.73 | u-Plasminogen activator |
cell surface |
on keratinocytes |
GO:0009986 AmiGO QuickGO |
683220 |
3.4.21.73 | u-Plasminogen activator |
cell surface |
the active form of uPA is bound to its high affinity receptor uPAR on the cell surface |
GO:0009986 AmiGO QuickGO |
683550 |
3.4.21.75 | Furin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
669442, 693230, 708753, 710165, 717827 |
3.4.21.76 | Myeloblastin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
684453, 685785, 688708 |
3.4.21.76 | Myeloblastin |
cell surface |
granulocytes and monocytes |
GO:0009986 AmiGO QuickGO |
683193 |
3.4.21.76 | Myeloblastin |
cell surface |
neutrophil |
GO:0009986 AmiGO QuickGO |
709758 |
3.4.21.76 | Myeloblastin |
cell surface |
strong correlation between PR3 and CD177 surface expression |
GO:0009986 AmiGO QuickGO |
688215 |
3.4.21.B21 | trepolisin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
-, 732466 |
3.4.21.B25 | PACE4 proprotein convertase |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
675881 |
3.4.21.B25 | PACE4 proprotein convertase |
cell surface |
activated at the cell surface where it is tethered to heparan sulfate proteoglycans |
GO:0009986 AmiGO QuickGO |
680190 |
3.4.21.B25 | PACE4 proprotein convertase |
cell surface |
the enzyme is constitutively secreted into the extracellular media and localizes at the cell surface and in the extracellular matrix |
GO:0009986 AmiGO QuickGO |
732179 |
3.4.21.B26 | proprotein convertase 5 |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
731899 |
3.4.21.B27 | proprotein convertase 7 |
cell surface |
only overexpressed PC7 activity reaches the cell surface, endosomes, and the trans-Golgi network |
GO:0009986 AmiGO QuickGO |
753199 |
3.4.21.B28 | fibroblast activation protein alpha subunit |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
650762, 707629, 717591, 731043, 752802 |
3.4.21.B6 | prostasin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
731623 |
3.4.21.B6 | prostasin |
cell surface |
prostasin is glycosylphosphatidylinositol-anchored to the cell surface |
GO:0009986 AmiGO QuickGO |
677453 |
3.4.21.B61 | transmembrane protease serine 11D |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
754529 |
3.4.22.15 | cathepsin L |
cell surface |
main localization. The 80-kDa precursor protein is noncovalently associated with the S-layer proteins, while the 47-kDa mature form is tightly associated with the underlying cell wall |
GO:0009986 AmiGO QuickGO |
727753 |
3.4.22.26 | cancer procoagulant |
cell surface |
loosely anchored on outside of cells |
GO:0009986 AmiGO QuickGO |
30159 |
3.4.22.27 | cathepsin S |
cell surface |
of vascular smooth muscle cells, by association with integrin alphanybeta3, surface distribution |
GO:0009986 AmiGO QuickGO |
667140 |
3.4.22.35 | Histolysain |
cell surface |
the enzyme is secreted and localized on the cell surface |
GO:0009986 AmiGO QuickGO |
668769 |
3.4.22.36 | caspase-1 |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
699419 |
3.4.22.37 | gingipain R |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
697200 |
3.4.22.51 | cruzipain |
cell surface |
the signaling factor NF-kB P65 colocalizes with cruzain on the cell surface of intracellular wild-type parasites |
GO:0009986 AmiGO QuickGO |
718307 |
3.4.22.B28 | calpain 8 |
cell surface |
mucous cells |
GO:0009986 AmiGO QuickGO |
665705 |
3.4.22.B5 | CPB protease |
cell surface |
attached to membrane domains via glycosylphophatidylinositol anchor |
GO:0009986 AmiGO QuickGO |
697814 |
3.4.23.24 | Candidapepsin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
-, 754172 |
3.4.23.24 | Candidapepsin |
cell surface |
Sap2 |
GO:0009986 AmiGO QuickGO |
707937 |
3.4.23.25 | saccharopepsin |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
-, 754333, 755660 |
3.4.23.46 | memapsin 2 |
cell surface |
- |
GO:0009986 AmiGO QuickGO |
638909 |
3.4.23.46 | memapsin 2 |
cell surface |
beta-secretase is a type 1 transmembrane protein present at the cell surface |
GO:0009986 AmiGO QuickGO |
700482 |
3.4.23.46 | memapsin 2 |
cell surface |
close interaction between BACE and low density lipoprotein receptor-related protein on the cell surface |
GO:0009986 AmiGO QuickGO |
669331 |