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BRENDA support

Information on EC 3.4.11.3 - cystinyl aminopeptidase

for references in articles please use BRENDA:EC3.4.11.3

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IUBMB Comments

A zinc-containing sialoglycoprotein In peptidase family M1 (membrane alanyl aminopeptidase family)

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Release of an N-terminal amino acid, Cys-/-Xaa-, in which the half-cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however

Synonyms
gp160, oxytocinase, p-lap, insulin-regulated aminopeptidase, vasopressinase, at4 receptor, cystine aminopeptidase, placental leucine aminopeptidase, otase, insulin-responsive aminopeptidase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Release of an N-terminal amino acid, Cys-/-Xaa-, in which the half-cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however
show the reaction diagram
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