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Results 1 - 10 of 13 > >>
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3diagnostics the increase in serum IRAP activity can be an indicator of a misregulation of vasopressin (AVP) function 753943
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine activities of soluble cystyl aminopeptidase do not differ between diabetic and control rats in both hippocampus and hypothalamus. Membrane-bound cystyl aminopeptidase is about 2.5foldincreased in the hypothalamus and 5fold increased in the hippocampus 682252
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine blocking of alpha-1adrenoceptor by doxazosin increases enzyme activity in male, but not in female thalamus. Increased capacity of males to degrade vasopressin and to regulate cardiovascular homeostasis 683515
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine development of stable second generation inhibitors of IRAP based on the AT4 ligands angiotensin IV or LVV-H7 may provide the opportunity for the development of therapeutics for memory loss in patients Altheimer's disease 667888
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine enzyme isoform IRAP is involved in increasing malignant potential of endometrial cancer mediated by insulin. Endometrial adenocarcinoma A-MEC cells expressing the enzyme exhibit a significant growth-stimulatory effect compared with control. They have a remarkably high level of p85PI3K protein and show a higher degree of AKT phosphorylation by insulin stimulation 683302
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine excessive activity of vasopressinase is probably responsible for gestational diabetes insipidus 699736
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine marked decrease of membrane-bound cystinyl aminopeptidase activity in clear cell renal carcinoma cell, papillary renal carcinoma cell, and chromophobe renal carcinoma cell compared to surrounding non-tumor tissue. Minor and non-significant changes of enzyme activity in soluble fractions of carcinoma cells 684051
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine Otsuka Long Evans Tokushima Fatty rats, model of type II Diabetes mellitus, show significantly lower cell surface IRAP equilibrium activity than control. Time to reach equilibrium is significantly longer and adipocytes isolated from the model rats demonstrate both a delay and a reduction in 3-O-methyl-D-glucose uptake 683907
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine P-LAP is an independent prognosticator of clinical outcome in patients with endometrial carcinoma. Assessment of the P-LAP status provides clinically useful prognostic information in patients with endometrial carcinoma 670450
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3medicine P-LAP is available for evaluation of avarian epithelial malignancy and also as target for molecular therapy 668753
Results 1 - 10 of 13 > >>