EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.184 | carbonyl reductase (NADPH) |
C2C12 cell |
- |
740534 |
1.14.11.27 | [histone H3]-dimethyl-L-lysine36 demethylase |
C2C12 cell |
- |
764642 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
C2C12 cell |
- |
753418 |
1.14.19.17 | sphingolipid 4-desaturase |
C2C12 cell |
- |
744398 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
C2C12 cell |
- |
671751 |
1.21.99.4 | thyroxine 5'-deiodinase |
C2C12 cell |
- |
715736 |
1.3.3.6 | acyl-CoA oxidase |
C2C12 cell |
- |
686539 |
1.5.3.16 | spermine oxidase |
C2C12 cell |
- |
692648, 723918 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
C2C12 cell |
- |
753905 |
2.3.1.255 | N-terminal amino-acid Nalpha-acetyltransferase NatA |
C2C12 cell |
- |
741046 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
C2C12 cell |
- |
719337 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
C2C12 cell |
- |
-, 755766, 758395 |
2.3.2.26 | HECT-type E3 ubiquitin transferase |
C2C12 cell |
- |
737267 |
2.3.2.27 | RING-type E3 ubiquitin transferase |
C2C12 cell |
- |
756750 |
2.4.1.1 | glycogen phosphorylase |
C2C12 cell |
- |
-, 736105 |
2.4.1.221 | peptide-O-fucosyltransferase |
C2C12 cell |
- |
694172 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
C2C12 cell |
- |
760043 |
2.4.2.30 | NAD+ ADP-ribosyltransferase |
C2C12 cell |
- |
671826 |
2.4.2.31 | NAD+-protein-arginine ADP-ribosyltransferase |
C2C12 cell |
- |
759729 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
C2C12 cell |
- |
759198 |
2.7.1.107 | diacylglycerol kinase (ATP) |
C2C12 cell |
- |
673518, 690696, 703106, 703142, 760647 |
2.7.1.138 | ceramide kinase |
C2C12 cell |
- |
-, 761586 |
2.7.1.150 | 1-phosphatidylinositol-3-phosphate 5-kinase |
C2C12 cell |
- |
737640 |
2.7.1.40 | pyruvate kinase |
C2C12 cell |
- |
710051 |
2.7.1.91 | sphingosine kinase |
C2C12 cell |
- |
704795 |
2.7.10.1 | receptor protein-tyrosine kinase |
C2C12 cell |
- |
693754 |
2.7.11.1 | non-specific serine/threonine protein kinase |
C2C12 cell |
- |
737612 |
2.7.11.11 | cAMP-dependent protein kinase |
C2C12 cell |
- |
-, 721701 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
C2C12 cell |
- |
694154 |
2.7.11.20 | elongation factor 2 kinase |
C2C12 cell |
- |
680859 |
2.7.11.24 | mitogen-activated protein kinase |
C2C12 cell |
- |
664067 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
C2C12 cell |
- |
704122 |
2.7.12.2 | mitogen-activated protein kinase kinase |
C2C12 cell |
- |
740693 |
2.7.4.3 | adenylate kinase |
C2C12 cell |
- |
692228 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
C2C12 cell |
- |
-, 703850, 722415 |
3.1.3.36 | phosphoinositide 5-phosphatase |
C2C12 cell |
- |
729995, 732083 |
3.1.3.48 | protein-tyrosine-phosphatase |
C2C12 cell |
- |
750465 |
3.1.3.56 | inositol-polyphosphate 5-phosphatase |
C2C12 cell |
- |
751561 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
C2C12 cell |
- |
732083 |
3.1.3.86 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
C2C12 cell |
- |
732083 |
3.1.4.11 | phosphoinositide phospholipase C |
C2C12 cell |
- |
679976, 716113 |
3.1.4.12 | sphingomyelin phosphodiesterase |
C2C12 cell |
- |
749539 |
3.1.4.4 | phospholipase D |
C2C12 cell |
- |
660975, 707551 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
C2C12 cell |
- |
752667 |
3.4.21.B25 | PACE4 proprotein convertase |
C2C12 cell |
- |
708949 |
3.4.22.15 | cathepsin L |
C2C12 cell |
- |
700963, 711141 |
3.4.22.52 | calpain-1 |
C2C12 cell |
- |
695462, 697162 |
3.4.22.53 | calpain-2 |
C2C12 cell |
- |
695462, 697162 |
3.4.22.54 | calpain-3 |
C2C12 cell |
- |
709092 |
3.4.22.56 | caspase-3 |
C2C12 cell |
- |
717792 |
3.4.22.61 | caspase-8 |
C2C12 cell |
- |
708073 |
3.4.22.62 | caspase-9 |
C2C12 cell |
- |
699106 |
3.4.22.B71 | SENP2 peptidase |
C2C12 cell |
- |
-, 731703, 732158, 754620 |
3.4.24.86 | ADAM 17 endopeptidase |
C2C12 cell |
- |
681016, 709939 |
3.4.24.B10 | ADAM12 endopeptidase |
C2C12 cell |
- |
680191 |
3.4.24.B11 | ADAMTS1 endopeptidase |
C2C12 cell |
- |
734360 |
4.1.1.17 | ornithine decarboxylase |
C2C12 cell |
- |
713718 |
6.1.1.4 | leucine-tRNA ligase |
C2C12 cell |
- |
744849 |
7.1.1.9 | cytochrome-c oxidase |
C2C12 cell |
- |
658633 |
1.14.11.51 | DNA N6-methyladenine demethylase |
C2C12 cell |
ALKBH1 enhances proliferation and inhibits differentiation of C2C12 cells |
764640 |
2.4.2.31 | NAD+-protein-arginine ADP-ribosyltransferase |
C2C12 cell |
ART1, ART3 and ART5 present in myotubes, absent, with the exception of ART3, from myoblasts |
702912 |
1.14.13.225 | F-actin monooxygenase |
C2C12 cell |
C2C12 and satellite cells require MICAL2 for myogenic differentiation |
764435 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
C2C12 cell |
CRL 1772 (ATCC) |
5119 |
2.4.1.1 | glycogen phosphorylase |
C2C12 cell |
cultured |
688369 |
2.7.1.107 | diacylglycerol kinase (ATP) |
C2C12 cell |
diacylglycerol kinase zeta and syntrophins, scaffold proteins of the dystrophin glycoprotein complex that bind directly to diacylglycerol kinase zeta, are spatially regulated during fusion of cultured cells. Both proteins accumulate with the GTPase Rac1 at sites where fine filopodia mediate the initial contact between myoblasts. Diacylglycerol kinase zeta codistributes with the Ca2+-dependent cell adhesion molecule N-cadherin at nascent cell contacts |
691687 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
C2C12 cell |
differentiated into myotubes |
713012 |
2.7.11.19 | phosphorylase kinase |
C2C12 cell |
differentiated muscle myoblasts |
662844 |
3.1.4.11 | phosphoinositide phospholipase C |
C2C12 cell |
differentiation of C2C12 myoblasts in response to mitogen withdrrawal and insulin stimulation is characterized by a marked increase in nuclear PI-PLCbeta1 |
678395 |
3.4.21.6 | coagulation factor Xa |
C2C12 cell |
enzyme elicits a signaling response. ERK1/2 phosphorylation by factor Xa is dependent on protease-activated receptor PAR-2 cleavage and leads to fibroblast proliferation, migration, and differentiation into myofibroblasts |
701355 |
3.2.1.18 | exo-alpha-sialidase |
C2C12 cell |
isoform Neu3 plays a key role in skeletal muscle differentiation by strictly modulating the ganglioside content of adjacent cells, with special regard to GM3 |
698860 |
2.7.11.20 | elongation factor 2 kinase |
C2C12 cell |
murine myoblasts |
687926 |
3.4.24.B10 | ADAM12 endopeptidase |
C2C12 cell |
myoblast cell line |
653221 |
3.4.24.B4 | matrix metalloproteinase-13 |
C2C12 cell |
myoblast cell line, expression of enzyme and tissue inhibitor of matrix metalloproteinase, TIMP-1, is regulated by Wnt signaling combined with bone morphogenic protein BMP-2 in osteoblastic differentiation |
668702 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
C2C12 cell |
myoblast cells |
661301 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
C2C12 cell |
myotube |
710841 |
2.7.11.22 | cyclin-dependent kinase |
C2C12 cell |
myotube cells |
666718 |
2.7.1.107 | diacylglycerol kinase (ATP) |
C2C12 cell |
nuclear DGKzeta increases during myogenic differentiation of mouse C2C12 myoblasts |
673918 |
2.7.1.107 | diacylglycerol kinase (ATP) |
C2C12 cell |
nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts |
673518 |
3.4.22.B66 | caspase-12 |
C2C12 cell |
skeletal muscle myoblast |
754246 |
1.5.3.16 | spermine oxidase |
C2C12 cell |
SMO transcript accumulation and enzymatic activity increases during C2C12 cell differentiation and correlates with the decrease of spermine content. Increased spermine oxidase (SMO) activity is a differentiation marker of myogenic C2C12 cells |
692648 |
2.7.11.4 | [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase |
C2C12 cell |
undifferentiated myoblast cell line |
662283 |
3.4.24.B10 | ADAM12 endopeptidase |
C2C12 cell |
yoblast cell line |
651993 |