Information on EC 2.7.10.1 - receptor protein-tyrosine kinase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY
2.7.10.1
-
RECOMMENDED NAME
GeneOntology No.
receptor protein-tyrosine kinase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in Metazoans [1]. In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
A-type platelet-derived growth factor receptor
P16234
-
Adhesion-related kinase
-
-
-
-
Adhesion-related kinase
Q00993
-
ALK receptor tyrosine kinase
-
-
ALK tyrosine kinase receptor
Q9UM73
-
ALK tyrosine kinase receptor
P97793
-
alpha platelet-derived growth factor receptor
P16234
-
alpha platelet-derived growth factor receptor
P26618
-
alpha platelet-derived growth factor receptor
P20786
-
alpha platelet-derived growth factor receptor
P26619
-
Anaplastic lymphoma kinase
-
-
-
-
Anaplastic lymphoma kinase
-
-
Anaplastic lymphoma kinase
-
-
Anaplastic lymphoma kinase
-
-
angiopoietin 1 receptor
Q06807
-
angiopoietin 1 receptor
O73791
-
angiopoietin 1 receptor
Q02763
-
angiopoietin 1 receptor
Q02858
-
ark
Q00993
-
Axl
P30530
-
AXL oncogene
-
-
-
-
basic fibroblast growth factor receptor 1
P21804
-
basic fibroblast growth factor receptor 1
P16092
-
basic fibroblast growth factor receptor 1
Q04589
-
basic-FGF receptor
P11362
-
BDNF/NT-3 growth factors receptor
Q9v6k3
-
BDNF/NT-3 growth factors receptor
Q91987
-
BDNF/NT-3 growth factors receptor
Q16620
-
BDNF/NT-3 growth factors receptor
P15209
-
BDNF/NT-3 growth factors receptor
Q63604
-
BEK/FGFR-2 receptor
P21803
-
beta platelet-derived growth factor receptor
P09619
-
beta platelet-derived growth factor receptor
P05622
-
brain specific kinase
Q60629
-
Brain-specific kinase
-
-
-
-
Breathless protein
-
-
-
-
c-erbB3
-
-
-
-
c-fgr
-
-
-
-
c-fms
-
-
-
-
c-kit
-
-
-
-
c-kit
-
-
c-kit
P05532
-
c-kit receptor
-
-
c-Kit receptor protein-tyrosine kinase
P10721
-
c-Kit receptor tyrosine kinase
-
-
c-Kit receptor tyrosine kinase
-
-
c-Kit RTK
-
-
c-Kit tyrosine kinase
-
-
-
-
c-kitR tyrosine kinase
P10721
-
C-mer
-
-
-
-
C-mer
-
-
c-met
-
-
-
-
c-met
Q2IBA6
-
c-met
P97523
-
c-Met receptor tyrosine kinase
-
-
c-Met receptor tyrosine kinase
P08581
-
c-Met RTK
-
-
C-ret
-
-
-
-
C-SRC
-
-
C14
-
-
-
-
Cadherin 96Ca
-
-
-
-
Cak I receptor
Q03146
-
CD115 antigen
-
-
-
-
CD117
-
-
CD117 antigen
-
-
-
-
CD135 antigen
-
-
-
-
CD136 antigen
-
-
-
-
CD140a antigen
-
-
-
-
CD140b antigen
-
-
-
-
CD167a antigen
-
-
-
-
CD202b antigen
-
-
-
-
CD220 antigen
-
-
-
-
CD221 antigen
-
-
-
-
CD246 antigen
-
-
-
-
CDW136
-
-
-
-
CEK4
-
-
-
-
Cek5
P28693
-
Cell adhesion kinase
-
-
-
-
chicken embryo kinase 5
P28693
-
cKit
-
-
class II receptor tyrosine kinase
P42159
-
colony-stimulating factor-1 receptor
-
-
CSF-1 receptor
-
also known as c-fms and CD115
DDR1
Q08345
-
DDR2
Q62371
-
Derailed protein
-
-
-
-
DFGF-R1
-
-
-
-
discoidin domain receptor 1
Q08345
-
discoidin domain receptor 2
Q16832
-
discoidin domain receptor 2
Q62371
-
discoidin domain receptor tyrosine kinase 1
Q08345
-
Discoidin receptor tyrosine kinase
-
-
-
-
Discoidin receptor tyrosine kinase
Q08345
-
Doughnut protein
-
-
-
-
Drl RTK
Q27324
-
Dror
-
-
-
-
Dror protein
Q24488
-
Drosophila relative of ERBB
-
-
-
-
DRT
-
-
-
-
DTK
P55144
-
DTK receptor tyrosine kinase
Q06418
-
EBK
-
-
-
-
EBK
Q61772
-
Eek receptor
O09127
-
EGF receptor
P24348
-
EGF receptor
-
-
EGF receptor protein-tyrosine kinase
-
-
EGF receptor tyrosine kinase
-
-
-
-
EGF receptor tyrosine kinase
-
-
EGF receptor tyrosine kinase
-
-
EGF receptor tyrosine kinase
-
-
EGF RPTK
-
-
EGF RTK
-
-
EGF TK
-
-
EGF-R
-
-
EGF-R
Q01279
-
EGF-receptor
-
-
Egfr
-
-
-
-
Egfr
-
-
Egfr
Q01279
-
EGFR protein tyrosine kinase
-
-
EGFR protein tyrosine kinase
-
-
EGFr TK
-
-
-
-
EGFR tyrosine kinase
P00533
-
EGFR tyrosine kinase
-
-
EGFR-tyrosine kinase
-
-
Egg laying defective protein 15
-
-
-
-
ELK
-
-
-
-
Elk tyrosine kinase
P09759
-
embryo brain kinase
Q61772
-
Embryonic brain kinase
-
-
-
-
embryonic receptor kinase
P35968
-
EmRK2
P35968
-
Endothelial kinase receptor EK1
-
-
-
-
Eph homologous kinase 3
P54759
-
Eph receptor tyrosine kinase
P54764
-
EPH-and ELK-related kinase
-
-
-
-
Eph-like kinase1
O13146
-
Eph-related receptor tyrosine kinase Cek9
Q07497
-
EphA1
-
-
EphA1 receptor
-
-
EPHA1 receptor tyrosine kinase
P21709
-
EphA2
P29317
-
EphA2
Q03145
-
EPHA4
P54764
-
ephrin receptor 1
O61460
-
ephrin type-A receptor 1
P21709
-
ephrin type-A receptor 2
P29317
-
ephrin type-A receptor 2
Q03145
-
ephrin type-A receptor 3
O13146
-
ephrin type-A receptor 3
P29318
-
ephrin type-A receptor 3
P29320
-
ephrin type-A receptor 3
P29319
-
ephrin type-A receptor 3
O08680
-
ephrin type-A receptor 4
Q07496
-
ephrin type-A receptor 4
P54764
-
ephrin type-A receptor 4
Q03137
-
ephrin type-A receptor 4A
Q91845
-
ephrin type-A receptor 4B
Q91694
-
ephrin type-A receptor 5
P54755
-
ephrin type-A receptor 5
P54756
-
ephrin type-A receptor 5
Q60629
-
ephrin type-A receptor 5
P54757
-
ephrin type-A receptor 6
Q62413
-
ephrin type-A receptor 7
O42422
-
ephrin type-A receptor 7
Q15375
-
ephrin type-A receptor 7
Q61772
-
ephrin type-A receptor 7
P54759
-
ephrin type-A receptor 8
P29322
-
ephrin type-A receptor 8
O09127
-
ephrin type-B receptor 1
P54762
-
ephrin type-B receptor 1
P09759
-
ephrin type-B receptor 1A
Q91571
-
ephrin type-B receptor 2
Q90344
-
ephrin type-B receptor 2
P28693
-
ephrin type-B receptor 2
P29323
-
ephrin type-B receptor 3
P54753
-
ephrin type-B receptor 3
P54754
-
ephrin type-B receptor 4
P54760
-
ephrin type-B receptor 4
P54761
-
ephrin type-B receptor 5
Q07497
-
ephrine receptor
-
-
epidermal growth factor receptor
-
-
epidermal growth factor receptor
P04412
-
epidermal growth factor receptor
-
-
epidermal growth factor receptor
P00533
-
epidermal growth factor receptor
-
-
epidermal growth factor receptor
Q01279
-
epidermal growth factor receptor
-
-
epidermal growth factor receptor 2
-
-
epidermal growth factor receptor 4
Q15303
-
epidermal growth factor receptor kinase
-
-
epidermal growth factor receptor tyrosine kinase
-
-
epidermal growth factor receptor tyrosine kinase
P00533
-
epidermal growth factor receptor tyrosine kinase
-
-
epidermal growth factor receptor tyrosine kinase inhibitor
-
-
Epidermal growth factor receptor-related protein
-
-
-
-
epidermal growth factor type II receptor
-
-
epidermal growth factor tyrosine protein kinase
-
-
epidermal growth factor-receptor
-
-
epidermal growth-factor receptor tyrosine kinase
-
-
Epithelial cell kinase
-
-
-
-
Epithelial cell kinase
P29317
-
epithelial discoidin domain receptor 1
Q08345
-
epithelial discoidin domain receptor 1
Q03146
-
epithelial discoidin domain receptor 1
Q63474
-
erb-B1
P00533
-
ErbB receptor protein-tyrosine kinase
-
-
erbB tyrosine kinase
-
-
-
-
ErbB-1
P00533
-
ErbB-2
P04626
-
ErbB-2
P70424
-
ErbB-4 receptor
Q15303
-
ErbB-4 tyrosine kinase
-
-
ERBB1
P00533
-
ErbB1 tyrosine kinase
-
-
ErbB2
Q61526
-
ErbB2
P06494
-
ErbB2 kinase
-
-
-
-
erbB2 receptor tyrosine kinase
-
-
erbB2 receptor tyrosine kinase
P04626
-
erbB2 receptor tyrosine kinase
-
-
erbB2 receptor tyrosine kinase
-
-
ErbB2 tyrosine kinase
-
-
ErbB3
Q61526
-
ErbB3 receptor tyrosine kinase
Q61526
-
ErbB4
-
-
ErbB4 receptor
-
-
ERK
-
-
-
-
erlotinib
-
-
ETK
-
-
-
-
fetal liver kinase 1
P35918
-
FGF receptor
P11362
-
FGF receptor tyrosine kinase
-
-
FGFR
-
-
FGFR
-
-
FGFR-4
P22455
-
FGFR1K
P11362
-
FGFR2
-
-
FGFR2
P21802
-
FGFR3
Q61851
-
FGFR4
-
-
FGFR4
Q03142
-
fibroblast growth factor receptor
-
-
fibroblast growth factor receptor
-
-
fibroblast growth factor receptor
-
-
fibroblast growth factor receptor 1
P11362
-
fibroblast growth factor receptor 1
P22182
-
fibroblast growth factor receptor 2
P21803
-
fibroblast growth factor receptor 2
Q01279
-
fibroblast growth factor receptor 2
Q03364
-
fibroblast growth factor receptor 3
Q61851
-
fibroblast growth factor receptor 4
P22455
-
fibroblast growth factor receptor 4
Q03142
-
fibroblast growth factor receptor 4
Q91742
-
fibroblast growth factor receptor BFR-2
P21802
-
fibroblast growth factor receptor homolog 1
Q07407
-
fibroblast growth factor receptor homolog 2
Q09147
-
FL cytokine receptor
Q00342
-
Flk-1
P52583
-
Flk-1
-
-
Flt-1
-
-
FLT3
P36888
-
FLT3 receptor protein
-
-
FLT3/FLK2 receptor tyrosine kinase
Q00342
-
FLT4
P35916
-
FLT4 receptor tyrosine kinase
P35916
-
Fms proto-oncogene
-
-
-
-
fms-like tyrosine kinase 3
-
-
GCTK
-
-
-
-
GCTK
P42159
-
GP145-TrkB
-
-
-
-
GP145-TrkB/GP95-TrkB
-
-
-
-
GP145-TrkC
-
-
-
-
gp145trkC
P24786
-
growth hormone receptor
-
-
Gurken receptor
-
-
-
-
Heartless protein
-
-
-
-
HEK
-
-
-
-
HEK
P29320
-
HEK 2
P54753
-
HEK3
-
-
-
-
HEK4
-
-
-
-
HEK6
-
-
-
-
Heparin-binding growth factor receptor
-
-
-
-
hepatocyte growth factor receptor
Q2IBA6
-
hepatocyte growth factor receptor
-
-
hepatocyte growth factor receptor
P08581
-
hepatocyte growth factor receptor
-
-
hepatocyte growth factor receptor
P16056
-
hepatocyte growth factor receptor
P97523
-
HER receptor protein-tyrosine kinase
-
-
HER-1
P00533
-
Her-2
P04626
-
Her1 tyrosine kinase
-
-
HER2
-
-
HER2
P04626
-
HER2
P70424
-
HER2neu
-
-
HER3
P21860
-
HER3/ERRB3
P21860
-
HGF receptor
-
-
-
-
HGF-SF receptor
-
-
-
-
high affinity nerve growth factor receptor
P04629
-
high affinity nerve growth factor receptor
P35739
-
HTK
P54760
-
HTL protein
Q07407
-
hydroxyaryl-protein kinase
-
-
-
-
HYK
-
-
-
-
HYK
Q02858
-
IGF-1 receptor
-
-
IGF-1R
P08069
-
IGF-1R
-
-
IGF-1R tyrosine kinase
-
-
IGFR tyrosine kinase
-
-
ILP receptor
-
-
-
-
ILP receptor
O02466
-
InRK
-
-
insulin receptor
-
-
insulin receptor
-
-
insulin receptor
P06213
-
insulin receptor
-
-
insulin receptor
P15208
-
insulin receptor
-
-
insulin receptor
P15127
-
insulin receptor kinase
-
-
insulin receptor kinase
-
-
insulin receptor kinase
-
-
insulin receptor protein tyrosine kinase
-
-
insulin receptor protein-tyrosine kinase
-
-
-
-
insulin receptor tyrosine kinase
-
-
insulin receptor tyrosine kinase
-
-
insulin receptor-beta subunit
-
-
insulin receptor-related protein
P14617
-
insulin receptor-related protein
P14616
-
insulin receptor-related protein
Q9wtl4
-
insulin receptor-related receptor
P24062
-
insulin RTK
P09208
-
insulin-growth factor-1 receptor
-
-
insulin-like growth factor 1 receptor
P08069
-
insulin-like growth factor I receptor
P08069
-
insulin-like growth factor I receptor
Q60751
-
insulin-like growth factor I receptor
P24062
-
insulin-like growth factor receptor
-
-
insulin-like growth factor type I receptor
-
-
Insulin-like growth factor-1 receptor
-
-
insulin-like growth factor-1 receptor kinase
-
-
Insulin-like Growth Factor-1 receptor tyrosine kinase
-
-
insulin-like peptide receptor
O02466
-
insulin-like receptor
Q93105
-
insulin-like receptor
P09208
-
insulin-receptor tyrosine kinase
-
-
IR kinase
-
-
iR-beta subunit
-
-
IR-PTK
-
-
IR-related receptor
-
-
-
-
IRK
-
-
-
-
IRR
-
-
-
-
IRR
P14616
-
IRR-protein tyrosine kinase
Q9wtl4
-
KDR
P35918
-
KDR
O08775
-
KDR/fetal liver kinase-1
-
-
KDR/Flk-1
-
-
Keratinocyte growth factor receptor
-
-
-
-
Keratinocyte growth factor receptor
-
-
Keratinocyte growth factor receptor
P21803
-
KGF receptor
-
-
KGF receptor
P21803
-
KGFR
-
-
Kinase insert domain receptor
-
-
-
-
Kinase NYK
-
-
-
-
Kinase VIK
-
-
-
-
Kit protein
Q08156
-
Kit protein-tyrosine kinase
-
-
Kit protein-tyrosine kinase
-
-
KIT receptor tyrosine kinase
-
-
leptin receptor
-
-
Let-23 receptor protein-tyrosine kinase
P24348
-
leukocyte tyrosine kinase receptor
P29376
-
leukocyte tyrosine kinase receptor
P08923
-
Linotte protein
-
-
-
-
ltk receptor tyrosine kinase
P08923
-
M-CSF receptor
-
-
macrophage colony stimulating factor I receptor
P13369
-
macrophage colony stimulating factor I receptor
P07333
-
macrophage colony stimulating factor I receptor
P09581
-
macrophage colony stimulating factor I receptor
Q00495
-
macrophage colony-stimulating factor receptor
-
-
macrophage colony-stimulating factor receptor
P09581
-
macrophage stimulating 1-receptor
-
-
macrophage-colony stimulating factor receptor
-
-
macrophage-stimulating protein receptor
Q04912
-
macrophage-stimulating protein receptor
Q62190
-
mast/stem cell growth factor receptor
P43481
-
mast/stem cell growth factor receptor
O97799
-
mast/stem cell growth factor receptor
Q28317
-
mast/stem cell growth factor receptor
Q28889
-
mast/stem cell growth factor receptor
Q08156
-
mast/stem cell growth factor receptor
P10721
-
mast/stem cell growth factor receptor
P05532
-
MDK1
Q61772
-
MEK4
-
-
-
-
melanoma receptor protein-tyrosine kinase
P13388
-
Mer receptor tyrosine kinase
Q60805
-
Mertk
Q60805
-
MET
-
-
MET
P08581
-
Met proto-oncogene tyrosine kinase
-
-
-
-
Met receptor-tyrosine kinase
-
-
Met-related kinase
-
-
-
-
Met/hepatocyte growth factor receptor tyrosine kinase
P08581
-
MFR
-
-
-
-
MIR
-
-
-
-
mouse developmental kinase 1
Q61772
-
mROR1
-
-
-
-
mROR2
-
-
-
-
MSP receptor
-
-
-
-
MST1R
-
-
muscle-specific receptor tyrosine kinase
-
-
muscle-specific receptor tyrosine kinase
Q61006
-
muscle-specific receptor-tyrosine kinase
-
-
MuSK
-
-
MuSK
Q61006
-
myoblast growth factor receptor egl-15
Q10656
-
nerve growth factor receptor
-
-
NET
-
-
-
-
NET
P54762
-
Neu
P06494
-
NEU proto-oncogene
-
-
-
-
neuregulin receptor ErbB-4
Q15303
-
Neurospecific receptor tyrosine kinase
-
-
-
-
neurotrophin tyrosine receptor kinase
-
-
neurotrophin tyrosine receptor kinase
P35739
-
NGF RPTK
-
-
non-receptor protein tyrosine kinase
-
-
NRTK
-
-
-
-
NT-3 growth factor receptor
Q91044
-
NT-3 growth factor receptor
Q16288
-
NT-3 growth factor receptor
Q03351
-
NT-3 growth factor receptor
P24786
-
nuclear growth factor tyrosine protein kinase
-
-
NUK
-
-
-
-
NYK/FLK-1
P35918
-
orphan receptor tyrosine kinase
-
-
P140 TEK
-
-
-
-
p140-TrkA
-
-
-
-
p145c-kit
P10721
-
p180erbB4
-
-
-
-
p185-Ron
-
-
-
-
p185erbB2
-
-
-
-
p190MET kinase
P08581
-
p72ITK/EMT
Q03526
-
p75 neurotrophin receptor
-
-
p75NTR
-
-
PAG
Q91694
-
Pagliaccio
-
-
-
-
PDGF A
P26619
-
PDGF beta-receptor
P09619
-
PDGF receptor
-
-
PDGF receptor
-
-
PDGF receptor tyrosine kinase
-
-
PDGF receptor tyrosine kinase
-
-
PDGF-alpha receptor
-
-
PDGF-beta receptor
-
-
PDGF-R-alpha
-
-
-
-
PDGF-R-beta
-
-
-
-
PDGFR
-
-
PDGFR kinase
-
-
-
-
PDGFR-alpha
-
-
PDGFR-alpha
-
isoform
PDGFR-beta
-
-
PDGFR-beta
-
isoform
PDGFR-beta
-
-
PDGFRB
P09619
-
PDGFRbeta
P09619
-
PKCdelta
-
-
platelet derived growth factor receptor-beta
P09619
-
platelet-derived growth factor receptor
-
-
platelet-derived growth factor receptor
-
-
platelet-derived growth factor receptor
-
-
platelet-derived growth factor receptor
-
-
platelet-derived growth factor receptor alpha
-
-
platelet-derived growth factor receptor alpha
P16234
-
platelet-derived growth factor receptor kinase
-
-
platelet-derived growth factor receptor-beta
-
-
platelet-derived growth factor RPTK
-
-
proline-rich tyrosinekinase
-
-
protein kinase Cdelta
-
-
protein kinase eck
P29317
-
protein receptor tyrosine kinase RTK 6
Q08345
-
Protein tyrosine kinase
-
-
Protein tyrosine kinase
-
-
Protein-tyrosine kinase byk
-
-
-
-
protein-tyrosine kinase ITK/EMT
Q03526
-
Protein-tyrosine kinase receptor MPK-11
-
-
-
-
Proto-oncogene tyrosine-protein kinase Kit
-
-
-
-
proto-oncogene tyrosine-protein kinase MER
Q12866
-
proto-oncogene tyrosine-protein kinase MER
Q60805
-
proto-oncogene tyrosine-protein kinase MER
P57097
-
proto-oncogene tyrosine-protein kinase receptor ret
P07949
-
proto-oncogene tyrosine-protein kinase receptor ret
P35546
-
proto-oncogene tyrosine-protein kinase ROS
P08922
-
Pyk-2
-
-
Quek2
P52583
-
rceptor protein-tyrosine kinase erbB-4
Q62956
-
recepteur d'origine nantais
-
-
recepteur d'origine nantais receptor tyrosine kinase
-
-
recepteur d'origine nantais receptor tyrosine kinase
-
-
Recepteur d’Origine Nantais
Q04912
-
receptor for macrophage colony-stimulating factor
-
-
receptor for stem cell factor
-
-
receptor protein tyrosine kinase
-
-
receptor protein tyrosine kinase RTK
Q16832
-
receptor protein-tyrosine kinase erbB-2
P04626
-
receptor protein-tyrosine kinase erbB-2
Q60553
-
receptor protein-tyrosine kinase erbB-2
P06494
-
receptor protein-tyrosine kinase erbB-3
P21860
-
receptor protein-tyrosine kinase erbB-3
Q62799
-
receptor protein-tyrosine kinase erbB-4
Q15303
-
Receptor protein-tyrosine kinase HEK11
-
-
-
-
Receptor protein-tyrosine kinase HEK5
-
-
-
-
Receptor protein-tyrosine kinase HEK7
-
-
-
-
Receptor protein-tyrosine kinase HEK8
-
-
-
-
Receptor protein-tyrosine kinase TKT
-
-
-
-
receptor PTK
-
-
receptor tyrosine kinase
O97799
-
receptor tyrosine kinase
-
-
receptor tyrosine kinase
P09208
-
receptor tyrosine kinase
-
-
receptor tyrosine kinase
P30530
-
receptor tyrosine kinase
P35590, Q02763
-
receptor tyrosine kinase
Q08345
-
receptor tyrosine kinase
-
-
receptor tyrosine kinase
-
-
receptor tyrosine kinase
P35739
-
receptor tyrosine kinase c-Kit
-
-
receptor tyrosine kinase c-Kit
P05532
-
receptor tyrosine kinase Cek8
Q07496
-
receptor tyrosine kinase EphA1
-
-
receptor tyrosine kinase EphA2
P29317
-
receptor tyrosine kinase EphA2
Q03145
-
Receptor tyrosine kinase MerTK
-
-
-
-
receptor tyrosine kinase RET
-
-
receptor tyrosine kinase RON
-
-
receptor tyrosine kinase ROR1
Q01973
-
receptor tyrosine kinase Ror2
Q01974
-
receptor tyrosine kinase Ror2
-
-
receptor tyrosine kinase Sek
Q03137
-
receptor tyrosine kinase Sky
Q06418
-
receptor tyrosine-protein kinase erbB-2
P06494
-
Receptor-activated Janus kinase
-
-
-
-
receptor-like protein tyrosine kinase bsk
Q60629
-
receptor-like protein-tyrosine kinase TK14
P21802
-
receptor-like tyrosine-protein kinase kin-15
P34891
-
receptor-like tyrosine-protein kinase kin-16
P34892
-
receptor-type tyrosine kinase termed Rse
Q06418
-
receptor-type tyrosine-protein kinase FLT3
P36888
-
recptor tyrosine kinase
-
-
RET oncogene protein
Q9vie4
-
Ret receptor tyrosine kinase
-
-
Ret receptor tyrosine kinase
-
-
Ret51
-
-
Ret9
-
-
RON receptor
Q62190
-
RON receptor tyrosine kinase
-
-
RON receptor tyrosine kinase
-
-
RON receptor tyrosine kinase
Q04912
-
RON receptor tyrosine kinase
-
-
RON receptor tyrosine kinase
-
-
RON receptor tyrosine kinase
Q62190
-
Ron tyrosine kinase receptor
Q04912
-
Ron/Stk receptor tyrosine kinase
Q62190
-
ROR1
-
-
ROR1
Q01973
-
RPTK
-
-
RPTK
-
-
RTK
-
-
-
-
RTK
Q02858
-
RTK
P35739
-
sam3 protein
Q61851
-
SCFR
-
-
-
-
sea receptor
-
-
Sek-1 receptor tyrosine kinase
Q91845
-
sevenless protein
P20806
-
sevenless receptor tyrosine kinase
-
-
sFlt-1
-
-
Sky receptor
P55146
-
sky receptor tyrosine kinase
P55146
-
Slow nerve growth factor receptor
-
-
-
-
soluble fms-like tyrosine kinase 1
-
-
sponge receptor tyrosine kinase
Q27656
-
Srcasm
P36888
-
stem cell derived tyrosine kinase
-
-
stem cell factor receptor
-
-
stem cell receptor
-
-
stem cell tyrosine kinase 1
P36888
-
Stem cell-derived tyrosine kinase
-
-
-
-
Stem cell-derived tyrosine kinase
-
-
STK-1
P36888
-
subclass III receptor tyrosine kinase
-
-
T-cell-specific kinase
Q03526
-
Tec family kinase EMT/ITK/TSK
Q03526
-
Tek receptor tyrosine kinase
Q02858
-
Tie-2
-
-
Tie1
-
-
Tie1
P35590
-
Tie2
Q02858
-
Torpedo protein
-
-
-
-
TRK1 transforming tyrosine kinase protein
-
-
-
-
TrkA
-
-
TrkA
Q16288
-
trkB
-
-
trkB
Q16288
-
trkB
Q63604
-
TrkB receptor
-
-
TrkB receptor
Q63604
-
TrkB tyrosine kinase
-
-
-
-
TrkC
-
-
TrkC
Q16288
-
TrkC
Q03351
-
TrkC receptor tyrosine kinases
Q03351
-
TrkC tyrosine kinase
-
-
-
-
Tsk
Q03526
-
Tunica interna endothelial cell kinase
-
-
-
-
Tyro 10 receptor tyrosine kinase
Q62371
-
Tyro 3
-
-
Tyrosine kinase
-
-
Tyrosine kinase CEK6 receptor
-
-
-
-
Tyrosine kinase DDR
-
-
-
-
tyrosine kinase domain of the insulin receptor
-
-
tyrosine kinase Emt/Itk
Q03526
-
tyrosine kinase p59fyn
P36888
-
tyrosine kinase QEK5
Q90344
-
tyrosine kinase receptor
-
-
tyrosine kinase receptor CEK2
P18460
-
tyrosine kinase receptor CEK3
P18461
-
Tyrosine kinase receptor HD-14
-
-
-
-
tyrosine kinase receptor HER2
P70424
-
tyrosine kinase receptor RON
-
-
tyrosine kinase receptor trkE
Q08345
-
Tyrosine kinase-type cell surface receptor HER2
-
-
-
-
Tyrosine kinase-type cell surface receptor HER3
-
-
-
-
Tyrosine kinase-type cell surface receptor HER4
-
-
-
-
Tyrosine-protein kinase CAK
-
-
-
-
Tyrosine-protein kinase CEK9
-
-
-
-
tyrosine-protein kinase Dnt
Q9v422
-
tyrosine-protein kinase Drl
Q27324
-
Tyrosine-protein kinase DTK
-
-
-
-
tyrosine-protein kinase Etk
P38134
-
tyrosine-protein kinase Etk
P58764
-
tyrosine-protein kinase Etk
Q8XC28
-
Tyrosine-protein kinase FLT3
-
-
-
-
Tyrosine-protein kinase FRT
-
-
-
-
tyrosine-protein kinase ITK/TSK
Q03526
-
tyrosine-protein kinase Ptk
O52788
-
Tyrosine-protein kinase receptor CEK10
-
-
-
-
Tyrosine-protein kinase receptor CEK11
-
-
-
-
Tyrosine-protein kinase receptor CEK5
-
-
-
-
Tyrosine-protein kinase receptor CEK7
-
-
-
-
Tyrosine-protein kinase receptor CEK8
-
-
-
-
Tyrosine-protein kinase receptor CEPHA7
-
-
-
-
Tyrosine-protein kinase receptor ECK
-
-
-
-
Tyrosine-protein kinase receptor EEK
-
-
-
-
Tyrosine-protein kinase receptor EPH
-
-
-
-
Tyrosine-protein kinase receptor ESK
-
-
-
-
Tyrosine-protein kinase receptor ETK1
-
-
-
-
Tyrosine-protein kinase receptor FLT
-
-
-
-
Tyrosine-protein kinase receptor FLT3
-
-
-
-
Tyrosine-protein kinase receptor FLT4
-
-
-
-
Tyrosine-protein kinase receptor HTK
-
-
-
-
Tyrosine-protein kinase receptor PAG
-
-
-
-
Tyrosine-protein kinase receptor QEK5
-
-
-
-
Tyrosine-protein kinase receptor REK4
-
-
-
-
Tyrosine-protein kinase receptor SEK
-
-
-
-
Tyrosine-protein kinase receptor TCK
-
-
-
-
Tyrosine-protein kinase receptor TEK
-
-
-
-
tyrosine-protein kinase receptor Tie-1
Q06805
-
tyrosine-protein kinase receptor Tie-1
P35590
-
tyrosine-protein kinase receptor Tie-1
Q06806
-
tyrosine-protein kinase receptor torso
P18475
-
tyrosine-protein kinase receptor TYRO3
Q06418
-
tyrosine-protein kinase receptor TYRO3
P55144
-
tyrosine-protein kinase receptor TYRO3
P55146
-
tyrosine-protein kinase receptor UFO
P30530
-
tyrosine-protein kinase receptor UFO
Q00993
-
Tyrosine-protein kinase receptor XEK
-
-
-
-
Tyrosine-protein kinase receptor XELK
-
-
-
-
Tyrosine-protein kinase receptor ZEK1
-
-
-
-
Tyrosine-protein kinase receptor ZEK2
-
-
-
-
Tyrosine-protein kinase receptor ZEK3
-
-
-
-
Tyrosine-protein kinase RSE
-
-
-
-
tyrosine-protein kinase RYK
P34925
-
tyrosine-protein kinase RYK
Q01887
-
Tyrosine-protein kinase SKY
-
-
-
-
tyrosine-protein kinase transforming protein erbB
P00535
-
tyrosine-protein kinase transforming protein erbB
P11273
-
tyrosine-protein kinase transforming protein erbB
Avian erythroblastosis virus ES4
P00535
;
-
tyrosine-protein kinase transforming protein erbB
Avian erythroblastosis virus ts167
P11273
-
-
tyrosine-protein kinase transforming protein erbB
P00534
-
tyrosine-protein kinase transforming protein kit
P04048
-
tyrosine-protein kinase transforming protein kit
Feline sarcoma virus Hardy-Zuckerman 4
P04048
-
-
tyrosine-protein kinase transforming protein RYK
P33497
-
tyrosine-protein kinase transmembrane receptor Ror
Q24488
-
tyrosine-protein kinase transmembrane receptor ROR1
Q01973
-
tyrosine-protein kinase transmembrane receptor ROR1
Q9z139
-
tyrosine-protein kinase transmembrane receptor ROR2
Q01974
-
tyrosine-protein kinase transmembrane receptor ROR2
Q9z138
-
tyrosine-protein kinase Wzc
P76387
-
tyrosine-protein kinase Wzc
Q8X7L9
-
tyrosine-protein kinase Wzc
Q8X7L9
-
-
VAB-1 Eph receptor tyrosine kinase
O61460
-
vascular endothelial growth factor
-
-
vascular endothelial growth factor 2
-
-
vascular endothelial growth factor receptor
-
-
vascular endothelial growth factor receptor
P35968
-
vascular endothelial growth factor receptor
-
-
vascular endothelial growth factor receptor
P35918
-
vascular endothelial growth factor receptor
-
-
vascular endothelial growth factor receptor
O08775
-
vascular endothelial growth factor receptor 1
P17948
-
vascular endothelial growth factor receptor 1
P53767
-
vascular endothelial growth factor receptor 2
P52583
-
vascular endothelial growth factor receptor 2
-
-
vascular endothelial growth factor receptor 2
-
-
vascular endothelial growth factor receptor 2
P35968
-
vascular endothelial growth factor receptor 2
P35918
-
vascular endothelial growth factor receptor 2
O08775
-
vascular endothelial growth factor receptor 3
P35916
-
vascular endothelial growth factor receptor 3
P35917
-
vascular endothelial growth factor receptor tyrosine kinase
-
-
vascular endothelial growth factor receptor-1
P35968
-
vascular endothelial growth-factor receptor-1 tyrosine kinase
-
-
Vascular permeability factor receptor
-
-
-
-
VEGF factor receptor tyrosine kinase
-
-
VEGF receptor
P35968
-
VEGF receptor
P35918
-
VEGF receptor
O08775
-
VEGF receptor 2
P52583
-
VEGF receptor tyrosine kinase
-
-
VEGF receptor-1
P35968
-
VEGF-receptor
-
-
VEGFR
-
-
VEGFR tyrosine kinase
-
-
VEGFR-1
-
-
VEGFR-1 tyrosine kinase
-
-
VEGFR-2
P35968
-
VEGFR-2
P35918
-
VEGFR-2
O08775
-
VEGFR-2 tyrosine kinase
P35968
-
VEGFR-3
-
-
VEGFR1
-
-
VEGFR1
-
isoform
VEGFR1-3
-
-
VEGFR2
-
-
VEGFR2
-
-
VEGFR2
-
isoform
VEGFR2/kinase domain region
-
-
VEGFR3
-
isoform
vitamin D receptor
-
-
Xek
Q91571
-
Xenopus Elk-like kinase
Q91571
-
MLN 19
-
-
-
-
additional information
-
EGFR tyrosine kinase, Her1 tyrosine kinase, ErbB1 tyrosine kinase are part of the plasma membrane receptor tyrosine kinase family
additional information
-
epidermal growth factor receptor is a member of the Erb family
additional information
-
Kit receptor is a type III protein-tyrosine kinase
additional information
-
the enzyme is a member of receptor-mediated PTK family
additional information
-
the enzyme is a member of the FGFR family
additional information
-
WebB and HER receptor protein-tyrosine kinase, as well as epidermal growth factor receptor belong to the ErbB family, overview
additional information
P00533
the enzymes belong to the epidermal growth factor receptor family, i.e. EGFR/ErbB family
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
strain ts167
SwissProt
Manually annotated by BRENDA team
Avian erythroblastosis virus ES4
strain ES4
SwissProt
Manually annotated by BRENDA team
Avian erythroblastosis virus ts167
strain ts167
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
grown in bovine BM and HCT-8 cells, parasite contains membrane proteins with EGF-like extracellular domains
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
strain O157
SwissProt
Manually annotated by BRENDA team
strain O157
SwissProt
Manually annotated by BRENDA team
strain Hardy-Zuckerman 4
SwissProt
Manually annotated by BRENDA team
Feline sarcoma virus Hardy-Zuckerman 4
strain Hardy-Zuckerman 4
SwissProt
Manually annotated by BRENDA team
ssp. catus
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
2 enzyme forms FGFR1 and FGFR2
-
-
Manually annotated by BRENDA team
2 isozymes PDGF-alpha receptor and PDGF-beta receptor, 4 isozymes FGFR-1, FGFR-2, FGFR-3, and FGFR-4
-
-
Manually annotated by BRENDA team
4 isozymes FGFR1-4
-
-
Manually annotated by BRENDA team
c-Met kinase
SwissProt
Manually annotated by BRENDA team
DDR1
SwissProt
Manually annotated by BRENDA team
EPHA4
SwissProt
Manually annotated by BRENDA team
epidermal growth factor receptor tyrosine kinase
SwissProt
Manually annotated by BRENDA team
ErbB1
SwissProt
Manually annotated by BRENDA team
IGF-1R
SwissProt
Manually annotated by BRENDA team
insulin-like growth factor 1 receptor
SwissProt
Manually annotated by BRENDA team
juxtamembrane domain and catalytic domains of c-Kit receptor protein-tyrosine kinase, residues 544-935
SwissProt
Manually annotated by BRENDA team
macrophage-stimulating protein receptor
SwissProt
Manually annotated by BRENDA team
MET
SwissProt
Manually annotated by BRENDA team
patients with chronic myelogenous leukemia
SwissProt
Manually annotated by BRENDA team
PDGFR-beta
SwissProt
Manually annotated by BRENDA team
PDGFRalpha
SwissProt
Manually annotated by BRENDA team
receptor-type tyrosine-protein kinase FLT3
SwissProt
Manually annotated by BRENDA team
several isozymes of both ErbB receptor protein-tyrosine kinase and HER receptor protein-tyrosine kinase
-
-
Manually annotated by BRENDA team
Southeast Asian acute myeloid leukemia patients
-
-
Manually annotated by BRENDA team
Mongolian gerbil
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Balb/c female mice
SwissProt
Manually annotated by BRENDA team
C57BL/6 mice
SwissProt
Manually annotated by BRENDA team
CD-1 mice, BALB/cJ mice and C57BL/6 mice
SwissProt
Manually annotated by BRENDA team
male ddY mice
-
-
Manually annotated by BRENDA team
strains C3H/HeJ and C57BL/6
-
-
Manually annotated by BRENDA team
wild-type 129/P3J mice and 129/SvJ SR-A-/- mice
SwissProt
Manually annotated by BRENDA team
grown in bovine BM and HCT-8 cells, parasite contains membrane proteins with EGF-like extracellular domains
-
-
Manually annotated by BRENDA team
New Zealand white rabbits
-
-
Manually annotated by BRENDA team
female Sprague-Dawley rats
SwissProt
Manually annotated by BRENDA team
female Wistar rats
-
-
Manually annotated by BRENDA team
male sprague-dawley rats
-
-
Manually annotated by BRENDA team
male Wistar rats
-
-
Manually annotated by BRENDA team
grown in bovine BM and HCT-8 cells, parasite contains membrane proteins with EGF-like extracellular domains
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)