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Literature summary for 3.4.24.B11 extracted from
- Adamts1 mediates ethanol-induced alterations in collagen and elastin via a FoxO1-sestrin3-AMPK signaling cascade in myocytes (2015), J. Cell. Biochem., 116, 91-101.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| TIMP3 | - |
Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P97857 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| C2C12 cell | - |
Mus musculus | - |
| myocyte | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADAMTS1 | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | incubation of myocytes with ethanol increases Adamt1 mRNA without changing the overall level of Adamts1 protein | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | silencing of Adamts1 blocks the adverse effects of ethanol on collagen and elastin levels | Mus musculus |
| metabolism | the enzyme is controlled by the FoxO1-sestrin 3-AMP-activated protein kinase signaling cascade and regulates ethanol-induced changes in collagen I and elastin levels | Mus musculus |
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