1.1.1.27: L-lactate dehydrogenase

This is an abbreviated version, for detailed information about L-lactate dehydrogenase, go to the full flat file.

Reaction

(S)-lactate
+
NAD+
=
pyruvate
+
NADH
+
H+

Synonyms

A4-LDH, AdhE, anaerobic lactate dehydrogenase, BbLDH, dehydrogenase, lactate, eLDHA, eLDHB, Epsilon crystallin, epsilon-crystallin, H4-L-lactate dehydrogenase, heart LDH, Immunogenic protein p36, L(+)-nLDH, L-(+)-lactate dehydrogenase, L-lactate dehydrogenase B, L-lactic acid dehydrogenase, L-lactic dehydrogenase, L-LDH, lactate dehydrogenase, lactate dehydrogenase A, lactate dehydrogenase B, lactate dehydrogenase NAD-dependent, lactic acid dehydrogenase, lactic dehydrogenase, LctD, LDH, LDH-1, LDH-2, LDH-3, LDH-4, LDH-5, LDH-A, LDH-A4, LDH-m4, LDH1, LDH2, LdhA, LDHB, mLDH, More, muscle LDH, NAD-lactate dehydrogenase, nitric oxideinducible l-lactate dehydrogenase, PfLDH, proteins, specific or class, anoxic stress response, p34, Sa-LDH-1, TeLdhL, Tsac_0416

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.27 L-lactate dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.27 - L-lactate dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.5 - 6
-
reduction of pyruvate
5 - 6.2
-
reduction of pyruvate
5 - 7
-
reduction of pyruvate, in presence of fructose 1,6-diphosphate
5.3
-
reduction of pyruvate
5.4
-
sodium acetate buffer
5.5
-
reduction of pyruvate
5.5 - 6
isozyme LDHB
5.5 - 7
-
reduction of pyruvate
5.6
-
reduction of pyruvate
5.8
pyruvate reduction, recombinant enzyme
6.9
-
in presence of fructose 1,6-diphosphate
7.2
-
oxidation of lactate
7.25
-
reduction of pyruvate, isoenzyme LDH-A2B2
7.3
-
reduction of pyruvate, isoenzyme I and II
7.8 - 8.8
-
oxidation of lactate, isoenzyme I and II
7.8
-
oxidation of lactate
8
-
reduction of pyruvate, in absence of fructose 1,6-diphosphate
8.5
-
oxidation of lactate
8.6
Molinema dessetae
-
oxidation of lactate
9
-
oxidation of lactate
9.1
-
oxidation of lactate
9.2
Agama stellio stellio
-
with lactate as substrate
9.5
-
glycine-NaOH buffer