Reference on EC 3.5.1.98 - histone deacetylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yeong Choi, K.; Ju Ji, Y.; Jee, C.; Kim, D.H.; Ahnn, J.
Characterization of CeHDA-7, a class II histone deacetylase interacting with MEF-2 in Caenorhabditis elegans
Biochem. Biophys. Res. Commun.
293
1295-1300
2002
Caenorhabditis elegans
Zou, H.; Wu, Y.; Navre, M.; Sang, B.C.
Characterization of the two catalytic domains in histone deacetylase 6
Biochem. Biophys. Res. Commun.
341
45-50
2006
Homo sapiens (Q9UBN7)
Riester, D.; Hildmann, C.; Gruenewald, S.; Beckers, T.; Schwienhorst, A.
Factors affecting the substrate specificity of histone deacetylases
Biochem. Biophys. Res. Commun.
357
439-445
2007
Homo sapiens
Song, Y.M.; Kim, Y.S.; Kim, D.; Lee, D.S.; Kwon, H.J.
Cloning, expression, and biochemical characterization of a new histone deacetylase-like protein from Thermus caldophilus GK24
Biochem. Biophys. Res. Commun.
361
55-61
2007
Thermus caldophilus, Thermus caldophilus GK24
Li, W.; Chen, H.Y.; Davie, J.R.
Properties of chicken erythrocyte histone deacetylase associated with the nuclear matrix
Biochem. J.
314
631-637
1996
Gallus gallus
-
Buggy, J.J.; Sideris, M.L.; Mak, P.; Lorimer, D.D.; McIntosh, B.; Clark, J.M.
Cloning and characterization of a novel human histone deacetylase, HDAC8
Biochem. J.
350
199-205
2000
Homo sapiens (Q9BY41), Homo sapiens
Sun, J.M.; Chen, H.Y.; Moniwa, M.; Samuel, S.; Davie, J.R.
Purification and characterization of chicken erythrocyte histone deacetylase 1
Biochemistry
38
5939-5947
1999
Gallus gallus (P56517), Gallus gallus
Lechner, T.; Lusser, A.; Pipal, A.; Brosch, G.; Loidl, A.; Goralik-Schramel, M.; Sendra, R.; Wegener, S.; Walton, J.D.; Loidl, P.
RPD3-Type Histone deacetylases in maize embryos
Biochemistry
39
1683-1692
2000
Zea mays (Q9ZTP8), Zea mays
Gantt, S.L.; Gattis, S.G.; Fierke, C.A.
Catalytic activity and inhibition of human histone deacetylase 8 is dependent on the identity of the active site metal ion
Biochemistry
45
6170-6178
2006
Homo sapiens (Q9BY41), Homo sapiens
Glenisson, W.; Castronovo, V.; Waltregny, D.
Histone deacetylase 4 is required for TGFbeta 1-induced myofibroblastic differentiation
Biochim. Biophys. Acta
1773
1572-1582
2007
Homo sapiens
Brogdon, J.L.; Xu, Y.; Szabo, S.J.; An, S.; Buxton, F.; Cohen, D.; Huang, Q.
Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function
Blood
109
1123-1130
2007
Homo sapiens
Harms, K.L.; Chen, X.
Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity
Cancer Res.
67
3145-3152
2007
Mus musculus
Myzak, M.C.; Hardin, K.; Wang, R.; Dashwood, R.H.; Ho, E.
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
Carcinogenesis
27
811-819
2006
Homo sapiens
Fong, P.M.; Tian, L.; Chen, Z.J.
Arabidopsis thaliana histone deacetylase 1 (AtHD1) is localized in euchromatic regions and demonstrates histone deacetylase activity in vitro
Cell Res.
16
479-488
2006
Arabidopsis thaliana (O22446), Arabidopsis thaliana
Mal, A.; Sturniolo, M.; Schiltz, R.L.; Ghosh, M.K.; Harter, M.L.
A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program
EMBO J.
20
1739-1753
2001
Homo sapiens
Hartman, H.B.; Yu, J.; Alenghat, T.; Ishizuka, T.; Lazar, M.A.
The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3
EMBO Rep.
6
445-451
2005
Mus musculus
Baidyaroy, D.; Brosch, G.; Graessle, S.; Trojer, P.; Walton, J.D.
Characterization of inhibitor-resistant histone deacetylase activity in plant-pathogenic fungi
Eukaryot. Cell
1
538-547
2002
Alternaria brassicicola, Bipolaris zeicola (Q8X1S4), Bipolaris zeicola, Pochonia chlamydosporia
Shwab, E.K.; Bok, J.W.; Tribus, M.; Galehr, J.; Graessle, S.; Keller, N.P.
Histone deacetylase activity regulates chemical diversity in Aspergillus
Eukaryot. Cell
6
1656-1664
2007
Aspergillus nidulans
Fischle, W.; Emiliani, S.; Hendzel, M.J.; Nagase, T.; Nomura, N.; Voelter, W.; Verdin, E.
A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p
J. Biol. Chem.
274
11713-11720
1999
Homo sapiens (P56524), Homo sapiens
Hu, E.; Chen, Z.; Fredrickson, T.; Zhu, Y.; Kirkpatrick, R.; Zhang, G.F.; Johanson, K.; Sung, C.M.; Liu, R.; Winkler, J.
Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor
J. Biol. Chem.
275
15254-15264
2000
Homo sapiens (Q9BY41), Homo sapiens
Huang, X.; Kadonaga, J.T.
Biochemical analysis of transcriptional repression by Drosophila histone deacetylase 1
J. Biol. Chem.
276
12497-12500
2001
Drosophila melanogaster
Fischle, W.; Dequiedt, F.; Fillion, M.; Hendzel, M.J.; Voelter, W.; Verdin, E.
Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo
J. Biol. Chem.
276
35826-35835
2001
Homo sapiens (Q8WUI4), Homo sapiens
Phiel, C.J.; Zhang, F.; Huang, E.Y.; Guenther, M.G.; Lazar, M.A.; Klein, P.S.
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
J. Biol. Chem.
276
36734-36741
2001
Homo sapiens
Pflum, M.K.H.; Tong, J.K.; Lane, W.S.; Schreiber, S.L.
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation
J. Biol. Chem.
276
47733-47741
2001
Homo sapiens
Kao, H.Y.; Lee, C.H.; Komarov, A.; Han, C.C.; Evans, R.M.
Isolation and characterization of mammalian HDAC10, a novel histone deacetylase
J. Biol. Chem.
277
187-193
2002
Homo sapiens (Q969S8)
Gao, L.; Cueto, M.A.; Asselbergs, F.; Atadja, P.
Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family
J. Biol. Chem.
277
25748-25755
2002
Homo sapiens (Q96DB2), Homo sapiens
Guardiola, A.R.; Yao, T.P.
Molecular cloning and characterization of a novel histone deacetylase HDAC10
J. Biol. Chem.
277
3350-3356
2002
Homo sapiens (Q969S8)
Johnson, C.A.; White, D.A.; Lavender, J.S.; O'Neill, L.P.; Turner, B.M.
Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70
J. Biol. Chem.
277
9590-9597
2002
Homo sapiens
Klampfer, L.; Huang, J.; Swaby, L.A.; Augenlicht, L.
Requirement of histone deacetylase activity for signaling by STAT1
J. Biol. Chem.
279
30358-30368
2004
Homo sapiens
Rossig, L.; Urbich, C.; Bruhl, T.; Dernbach, E.; Heeschen, C.; Chavakis, E.; Sasaki, K.; Aicher, D.; Diehl, F.; Seeger, F.; Potente, M.; Aicher, A.; Zanetta, L.; Dejana, E.; Zeiher, A.M.; Dimmeler, S.
Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells
J. Exp. Med.
201
1825-1835
2005
Mus musculus
Suzuki, T.; Nagano, Y.; Kouketsu, A.; Matsuura, A.; Maruyama, S.; Kurotaki, M.; Nakagawa, H.; Miyata, N.
Novel Inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates
J. Med. Chem.
48
1019-1032
2005
Homo sapiens (Q9BY41), Homo sapiens
Liu, T.; Kapustin, G.; Etzkorn, F.A.
Design and synthesis of a potent histone deacetylase inhibitor
J. Med. Chem.
50
2003-2006
2007
Homo sapiens
Han, A.; He, J.; Wu, Y.; Liu, J.O.; Chen, L.
Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2
J. Mol. Biol.
345
91-102
2004
Homo sapiens
Broide, R.S.; Redwine, J.M.; Aftahi, N.; Young, W.; Bloom, F.E.; Winrow, C.J.
Distribution of histone deacetylases 1-11 in the rat brain
J. Mol. Neurosci.
31
47-58
2007
Rattus norvegicus
Finnin, M.S.; Donigian, J.R.; Cohen, A.; Richon, V.M.; Rifkind, R.A.; Marks, P.A.; Breslow, R.; Pavletich, N.P.
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
Nature
401
188-190
1999
Aquifex aeolicus
Tong, J.J.; Liu, J.; Bertos, N.R.; Yang, X.J.
Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain
Nucleic Acids Res.
30
1114-1123
2002
Homo sapiens (Q969S8), Homo sapiens
Trojer, P.; Brandtner, E.M.; Brosch, G.; Loidl, P.; Galehr, J.; Linzmaier, R.; Haas, H.; Mair, K.; Tribus, M.; Graessle, S.
Histone deacetylases in fungi: novel members, new facts
Nucleic Acids Res.
31
3971-3981
2003
Aspergillus nidulans (Q7Z8L7), Aspergillus nidulans (Q7Z8L9)
Vannini, A.; Volpari, C.; Filocamo, G.; Casavola, E.C.; Brunetti, M.; Renzoni, D.; Chakravarty, P.; Paolini, C.; De Francesco, R.; Gallinari, P.; Steinkuhler, C.; Di Marco, S.
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor
Proc. Natl. Acad. Sci. USA
101
15064-15069
2004
Homo sapiens (Q9BY41), Homo sapiens
Guo, L.; Han, A.; Bates, D.L.; Cao, J.; Chen, L.
Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains
Proc. Natl. Acad. Sci. USA
104
4297-4302
2007
Homo sapiens (P56524), Homo sapiens
Hassig, C.A.; Tong, J.K.; Fleischer, T.C.; Owa, T.; Grable, P.G.; Ayer, D.E.; Schreiber, S.L.
A role for histone deacetylase activity in HDAC1-mediated transcriptional repression
Proc. Natl. Acad. Sci. USA
95
3519-3524
1998
Homo sapiens
Zhou, X.; Marks, P.A.; Rifkind, R.A.; Richon, V.M.
Cloning and characterization of a histone deacetylase, HDAC9
Proc. Natl. Acad. Sci. USA
98
10572-10577
2001
Homo sapiens (Q9UKV0), Homo sapiens
Geiger, R.C.; Kaufman, C.D.; Lam, A.P.; Budinger, G.R.; Dean, D.A.
Tubulin acetylation and histone deacetylase 6 activity in the lung under cyclic load
Am. J. Respir. Cell Mol. Biol.
40
76-82
2009
Homo sapiens, Mus musculus (Q9Z2V5), Mus musculus
Han, Y.; Jeong, H.M.; Jin, Y.H.; Kim, Y.J.; Jeong, H.G.; Yeo, C.Y.; Lee, K.Y.
Acetylation of histone deacetylase 6 by p300 attenuates its deacetylase activity
Biochem. Biophys. Res. Commun.
383
88-92
2009
Homo sapiens
Osoata, G.O.; Yamamura, S.; Ito, M.; Vuppusetty, C.; Adcock, I.M.; Barnes, P.J.; Ito, K.
Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2
Biochem. Biophys. Res. Commun.
384
366-371
2009
Homo sapiens, Homo sapiens (Q92769)
Dowling, D.P.; Gantt, S.L.; Gattis, S.G.; Fierke, C.A.; Christianson, D.W.
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors
Biochemistry
47
13554-13563
2008
Homo sapiens (Q9BY41), Homo sapiens
Perrino, E.; Cappelletti, G.; Tazzari, V.; Giavini, E.; Del Soldato, P.; Sparatore, A.
New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity
Bioorg. Med. Chem. Lett.
18
1893-1897
2008
Homo sapiens
Mai, A.; Perrone, A.; Nebbioso, A.; Rotili, D.; Valente, S.; Tardugno, M.; Massa, S.; De Bellis, F.; Altucci, L.
Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities
Bioorg. Med. Chem. Lett.
18
2530-2535
2008
Homo sapiens
Wang, H.; Yu, N.; Song, H.; Chen, D.; Zou, Y.; Deng, W.; Lye, P.L.; Chang, J.; Ng, M.; Sun, E.T.; Sangthongpitag, K.; Wang, X.; Wu, X.; Khng, H.H.; Fang, L.; Goh, S.K.; Ong, W.C.; Bonday, Z.; Stuenkel, W.; Poulsen, A.; Entzeroth, M.
N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity
Bioorg. Med. Chem. Lett.
19
1403-1408
2009
Homo sapiens
Chen, P.C.; Patil, V.; Guerrant, W.; Green, P.; Oyelere, A.K.
Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group
Bioorg. Med. Chem.
16
4839-4853
2008
Homo sapiens
Balasubramanian, S.; Verner, E.; Buggy, J.J.
Isoform-specific histone deacetylase inhibitors: The next step?
Cancer Lett.
280
211-221
2009
Homo sapiens
Jung, J.C.; Moon, H.I.; Oh, S.
Synthesis, structural characterization and biological evaluation of N-protected cyclopropylethylcarbamates as potential histone deacetylase inhibitor
Chem. Biol. Drug Des.
72
592-595
2008
Homo sapiens
Kee, H.J.; Eom, G.H.; Joung, H.; Shin, S.; Kim, J.R.; Cho, Y.K.; Choe, N.; Sim, B.W.; Jo, D.; Jeong, M.H.; Kim, K.K.; Seo, J.S.; Kook, H.
Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy
Circ. Res.
103
1259-1269
2008
Mus musculus (P70288)
Farooq, M.; Sulochana, K.N.; Pan, X.; To, J.; Sheng, D.; Gong, Z.; Ge, R.
Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish
Dev. Biol.
317
336-353
2008
Danio rerio (Q803C3), Danio rerio
Knutson, S.K.; Chyla, B.J.; Amann, J.M.; Bhaskara, S.; Huppert, S.S.; Hiebert, S.W.
Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
EMBO J.
27
1017-1028
2008
Mus musculus (O88895), Mus musculus
Nian, H.; Delage, B.; Ho, E.; Dashwood, R.H.
Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds
Environ. Mol. Mutagen.
50
213-221
2009
Homo sapiens (Q9BY41), Homo sapiens
Liu, H.; Hu, Q.; Dercole, A.J.; Ye, P.
Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells
Glia
57
1-12
2009
Rattus norvegicus (B2GUW3)
Xiong, S.D.; Yu, K.; Liu, X.H.; Yin, L.H.; Kirschenbaum, A.; Yao, S.; Narla, G.; Difeo, A.; Wu, J.B.; Yuan, Y.; Ho, S.M.; Lam, Y.W.; Levine, A.C.
Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells
Int. J. Cancer
125
774-782
2009
Homo sapiens (Q13547)
Montero, A.; Beierle, J.M.; Olsen, C.A.; Ghadiri, M.R.
Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures
J. Am. Chem. Soc.
131
3033-3041
2009
Homo sapiens
Schuetz, A.; Min, J.; Allali-Hassani, A.; Schapira, M.; Shuen, M.; Loppnau, P.; Mazitschek, R.; Kwiatkowski, N.P.; Lewis, T.A.; Maglathin, R.L.; McLean, T.H.; Bochkarev, A.; Plotnikov, A.N.; Vedadi, M.; Arrowsmith, C.H.
Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity
J. Biol. Chem.
283
11355-11363
2008
Homo sapiens (Q8WUI4), Homo sapiens
Tischler, J.L.; Abuaita, B.; Cuthpert, S.C.; Fage, C.; Murphy, K.; Saxe, A.; Furr, E.B.; Hedrick, J.; Meyers, J.; Snare, D.; Zand, A.R.
Simple inhibitors of histone deacetylase activity that combine features of short-chain fatty acid and hydroxamic acid inhibitors
J. Enzyme Inhib. Med. Chem.
23
549-555
2008
Rattus norvegicus
Jones, P.; Altamura, S.; De Francesco, R.; Paz, O.G.; Kinzel, O.; Mesiti, G.; Monteagudo, E.; Pescatore, G.; Rowley, M.; Verdirame, M.; Steinkuehler, C.
A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo
J. Med. Chem.
51
2350-2353
2008
Homo sapiens
Weerasinghe, S.V.; Estiu, G.; Wiest, O.; Pflum, M.K.
Residues in the 11 A channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors
J. Med. Chem.
51
5542-5551
2008
Homo sapiens (Q13547)
Patel, V.; Mazitschek, R.; Coleman, B.; Nguyen, C.; Urgaonkar, S.; Cortese, J.; Barker, R.H.; Greenberg, E.; Tang, W.; Bradner, J.E.; Schreiber, S.L.; Duraisingh, M.T.; Wirth, D.F.; Clardy, J.
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum
J. Med. Chem.
52
2185-2187
2009
Plasmodium falciparum (Q7K6A1), Plasmodium falciparum
Wallace, D.M.; Cotter, T.G.
Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina
J. Neurosci. Res.
87
887-905
2009
Mus musculus
Wang, J.C.; Chen, C.; Dumlao, T.; Naik, S.; Chang, T.; Xiao, Y.Y.; Sominsky, I.; Burton, J.
Enhanced histone deacetylase enzyme activity in primary myelofibrosis
Leuk. Lymphoma
49
2321-2327
2008
Homo sapiens
Duong, V.; Bret, C.; Altucci, L.; Mai, A.; Duraffourd, C.; Loubersac, J.; Harmand, P.O.; Bonnet, S.; Valente, S.; Maudelonde, T.; Cavailles, V.; Boulle, N.
Specific activity of class II histone deacetylases in human breast cancer cells
Mol. Cancer Res.
6
1908-1919
2008
Homo sapiens, Homo sapiens (P56524), Homo sapiens (Q13547), Homo sapiens (Q92769), Homo sapiens (Q9BY41)
Ray, S.; Lee, C.; Hou, T.; Boldogh, I.; Brasier, A.R.
Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution
Nucleic Acids Res.
36
4510-4520
2008
Homo sapiens (Q13547), Homo sapiens
Bowers, A.A.; West, N.; Newkirk, T.L.; Troutman-Youngman, A.E.; Schreiber, S.L.; Wiest, O.; Bradner, J.E.; Williams, R.M.
Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold
Org. Lett.
11
1301-1304
2009
Homo sapiens, Homo sapiens (Q13547), Homo sapiens (Q92769), Homo sapiens (Q9UBN7)
Ishii, S.; Kurasawa, Y.; Wong, J.; Yu-Lee, L.Y.
Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment
Proc. Natl. Acad. Sci. USA
105
4179-4184
2008
Homo sapiens
Zhou, J.; Vos, C.C.; Gjyrezi, A.; Yoshida, M.; Khuri, F.R.; Tamanoi, F.; Giannakakou, P.
The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner
J. Biol. Chem.
284
9648-9655
2009
Homo sapiens
Kawabata, T.; Nishida, K.; Takasugi, K.; Ogawa, H.; Sada, K.; Kadota, Y.; Inagaki, J.; Hirohata, S.; Ninomiya, Y.; Makino, H.
Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis
Arthritis Res. Ther.
12
R133
2010
Homo sapiens
Hu, Y.; Qin, F.; Huang, L.; Sun, Q.; Li, C.; Zhao, Y.; Zhou, D.X.
Rice histone deacetylase genes display specific expression patterns and developmental functions
Biochem. Biophys. Res. Commun.
388
266-271
2009
Oryza sativa Indica Group, Oryza sativa Japonica Group (Q2QWU2), Oryza sativa Japonica Group (Q5VP94), Oryza sativa Japonica Group (Q6YV04)
Zhuang, Y.; Nguyen, H.T.; Lasky, J.A.; Cao, S.; Li, C.; Hu, J.; Guo, X.; Burow, M.E.; Shan, B.
Requirement of a novel splicing variant of human histone deacetylase 6 for TGF-beta1-mediated gene activation
Biochem. Biophys. Res. Commun.
392
608-613
2010
Homo sapiens
Chetan, B.; Bunha, M.; Jagrat, M.; Sinha, B.N.; Saiko, P.; Graser, G.; Szekeres, T.; Raman, G.; Rajendran, P.; Moorthy, D.; Basu, A.; Jayaprakash, V.
Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity
Bioorg. Med. Chem. Lett.
20
3906-3910
2010
Homo sapiens (Q9BY41), Homo sapiens
Bora-Tatar, G.; Dayangac-Erden, D.; Demir, A.S.; Dalkara, S.; Yelekci, K.; Erdem-Yurter, H.
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
Bioorg. Med. Chem.
17
5219-5228
2009
Homo sapiens (Q9BY41), Homo sapiens
Zhang, Y.; Feng, J.; Liu, C.; Zhang, L.; Jiao, J.; Fang, H.; Su, L.; Zhang, X.; Zhang, J.; Li, M.; Wang, B.; Xu, W.
Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel histone deacetylases (HDACs) inhibitors
Bioorg. Med. Chem.
18
1761-1772
2010
Homo sapiens (Q9BY41)
Davies, G.F.; Ross, A.R.; Arnason, T.G.; Juurlink, B.H.; Harkness, T.A.
Troglitazone inhibits histone deacetylase activity in breast cancer cells
Cancer Lett.
288
236-250
2010
Homo sapiens
Liu, R.; Wang, L.; Chen, G.; Katoh, H.; Chen, C.; Liu, Y.; Zheng, P.
FOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locus
Cancer Res.
69
2252-2259
2009
Homo sapiens
Nian, H.; Bisson, W.H.; Dashwood, W.M.; Pinto, J.T.; Dashwood, R.H.
Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells
Carcinogenesis
30
1416-1423
2009
Homo sapiens (Q9BY41), Homo sapiens
Hui, S.; Brunt, K.; Husain, M.
Temporal and spatial regulation of histone deacetylase-7 and beta-catenin in endothelial cells
Circ. Res.
106
1180-1183
2010
Homo sapiens
Fiesel, F.C.; Voigt, A.; Weber, S.S.; Van den Haute, C.; Waldenmaier, A.; Goerner, K.; Walter, M.; Anderson, M.L.; Kern, J.V.; Rasse, T.M.; Schmidt, T.; Springer, W.; Kirchner, R.; Bonin, M.; Neumann, M.; Baekelandt, V.; Alunni-Fabbroni, M.; Schulz, J.B.; Kahle, P.J.
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
EMBO J.
29
209-221
2010
Homo sapiens
Halbert, J.; Ayong, L.; Equinet, L.; Le Roch, K.; Hardy, M.; Goldring, D.; Reininger, L.; Waters, N.; Chakrabarti, D.; Doerig, C.
A Plasmodium falciparum transcriptional cyclin-dependent kinase-related kinase with a crucial role in parasite proliferation associates with histone deacetylase activity
Eukaryot. Cell
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952-959
2010
Plasmodium falciparum
Hong, S.; Derfoul, A.; Pereira-Mouries, L.; Hall, D.J.
A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes
FASEB J.
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3539-3552
2009
Homo sapiens
Hayashi, A.; Horiuchi, A.; Kikuchi, N.; Hayashi, T.; Fuseya, C.; Suzuki, A.; Konishi, I.; Shiozawa, T.
Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin
Int. J. Cancer
127
1332-1346
2010
Homo sapiens
Luo, Y.; Jian, W.; Stavreva, D.; Fu, X.; Hager, G.; Bungert, J.; Huang, S.; Qiu, Y.
Trans-regulation of histone deacetylase activities through acetylation
J. Biol. Chem.
284
34901-34910
2009
Homo sapiens
Doyle, K.; Fitzpatrick, F.A.
Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function
J. Biol. Chem.
285
17417-17424
2010
Homo sapiens
Gantt, S.L.; Joseph, C.G.; Fierke, C.A.
Activation and inhibition of histone deacetylase 8 by monovalent cations
J. Biol. Chem.
285
6036-6043
2010
Homo sapiens
Ontoria, J.M.; Altamura, S.; Di Marco, A.; Ferrigno, F.; Laufer, R.; Muraglia, E.; Palumbi, M.C.; Rowley, M.; Scarpelli, R.; Schultz-Fademrecht, C.; Serafini, S.; Steinkuehler, C.; Jones, P.
Identification of novel, selective, and stable inhibitors of class II histone deacetylases. Validation studies of the inhibition of the enzymatic activity of HDAC4 by small molecules as a novel approach for cancer therapy
J. Med. Chem.
52
6782-6789
2009
Homo sapiens
Lee, K.H.; Choi, E.Y.; Kim, M.K.; Kim, K.O.; Jang, B.I.; Kim, S.W.; Kim, S.W.; Song, S.K.; Kim, J.R.
Inhibition of histone deacetylase activity down-regulates urokinase plasminogen activator and matrix metalloproteinase-9 expression in gastric cancer
Mol. Cell. Biochem.
343
163-171
2010
Homo sapiens
Lee, J.; Jeong, E.; Choi, M.; Kim, S.; Park, J.; Song, S.; Park, J.; Bang, Y.; Kim, T.
Inhibition of histone deacetylase 10 induces thioredoxin-interacting protein and causes accumulation of reactive oxygen species in SNU-620 human gastric cancer cells
Mol. Cells
30
107-112
2010
Homo sapiens
Hutt, D.M.; Herman, D.; Rodrigues, A.P.; Noel, S.; Pilewski, J.M.; Matteson, J.; Hoch, B.; Kellner, W.; Kelly, J.W.; Schmidt, A.; Thomas, P.J.; Matsumura, Y.; Skach, W.R.; Gentzsch, M.; Riordan, J.R.; Sorscher, E.J.; Okiyoneda, T.; Yates, J.R.; Lukacs, G.L.; Frizzell, R.A.; Manning, G.; Gottesfeld, J.M.; Balc, B.a.l.c.h.
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis
Nat. Chem. Biol.
6
25-33
2010
Homo sapiens
Jawerka, M.; Colak, D.; Dimou, L.; Spiller, C.; Lagger, S.; Montgomery, R.L.; Olson, E.N.; Wurst, W.; Goettlicher, M.; Goetz, M.
The specific role of histone deacetylase 2 in adult neurogenesis
Neuron Glia Biol.
6
93-107
2010
Mus musculus
Leone, V.; Mansueto, G.; Pierantoni, G.M.; Tornincasa, M.; Merolla, F.; Cerrato, A.; Santoro, M.; Grieco, M.; Scaloni, A.; Celetti, A.; Fusco, A.
CCDC6 represses CREB1 activity by recruiting histone deacetylase 1 and protein phosphatase 1
Oncogene
29
4341-4351
2010
Homo sapiens
Gao, D.J.; Xu, M.; Zhang, Y.Q.; Du, Y.Q.; Gao, J.; Gong, Y.F.; Man, X.H.; Wu, H.Y.; Jin, J.; Xu, G.M.; Li, Z.S.
Upregulated histone deacetylase 1 expression in pancreatic ductal adenocarcinoma and specific siRNA inhibits the growth of cancer cells
Pancreas
39
994-1001
2010
Homo sapiens
Demetriou, K.; Kapazoglou, A.; Tondelli, A.; Francia, E.; Stanca, M.A.; Bladenopoulos, K.; Tsaftaris, A.S.
Epigenetic chromatin modifiers in barley: I. Cloning, mapping and expression analysis of the plant specific HD2 family of histone deacetylases from barley, during seed development and after hormonal treatment
Physiol. Plant.
136
358-368
2009
Hordeum vulgare (C1IC97), Hordeum vulgare (C1IC98)
Kim, I.A.; No, M.; Lee, J.M.; Shin, J.H.; Oh, J.S.; Choi, E.J.; Kim, I.H.; Atadja, P.; Bernhard, E.J.
Epigenetic modulation of radiation response in human cancer cells with activated EGFR or HER-2 signaling: potential role of histone deacetylase 6
Radiother. Oncol.
92
125-132
2009
Homo sapiens
Janzer, A.; Lim, S.; Fronhoffs, F.; Niazy, N.; Buettner, R.; Kirfel, J.
Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components
Biochem. Biophys. Res. Commun.
421
665-670
2012
Homo sapiens
Shultz, M.; Fan, J.; Chen, C.; Cho, Y.S.; Davis, N.; Bickford, S.; Buteau, K.; Cao, X.; Holmqvist, M.; Hsu, M.; Jiang, L.; Liu, G.; Lu, Q.; Patel, C.; Suresh, J.R.; Selvaraj, M.; Urban, L.; Wang, P.; Yan-Neale, Y.; Whitehead, L.; Zhang, H.; Zhou, L.; Atadja, P.
The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors
Bioorg. Med. Chem. Lett.
21
4909-4912
2011
Homo sapiens
Singh, R.K.; Mandal, T.; Balsubramanian, N.; Viaene, T.; Leedahl, T.; Sule, N.; Cook, G.; Srivastava, D.K.
Histone deacetylase activators: N-acetylthioureas serve as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate
Bioorg. Med. Chem. Lett.
21
5920-5923
2011
Homo sapiens
Guan, P.; Sun, F.; Hou, X.; Wang, F.; Yi, F.; Xu, W.; Fang, H.
Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors
Bioorg. Med. Chem.
20
3865-3872
2012
Homo sapiens
Henkes, L.M.; Haus, P.; Jaeger, F.; Ludwig, J.; Meyer-Almes, F.J.
Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-octanediamides as inhibitors of human histone deacetylases
Bioorg. Med. Chem.
20
985-995
2012
Homo sapiens
Feng, J.H.; Jing, F.B.; Fang, H.; Gu, L.C.; Xu, W.F.
Expression, purification, and S-nitrosylation of recombinant histone deacetylase 8 in Escherichia coli
Biosci. Trends
5
17-22
2011
Homo sapiens (Q9BY41), Homo sapiens
Carneiro, K.; Donnet, C.; Rejtar, T.; Karger, B.; Barisone, G.; Daz, E.; Kortagere, S.; Lemire, J.; Levin, M.
Histone deacetylase activity is necessary for left-right patterning during vertebrate development
BMC Dev. Biol.
11
29
2011
Xenopus laevis
Mihaylova, M.M.; Vasquez, D.S.; Ravnskjaer, K.; Denechaud, P.D.; Yu, R.T.; Alvarez, J.G.; Downes, M.; Evans, R.M.; Montminy, M.; Shaw, R.J.
Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis
Cell
145
607-621
2011
Mus musculus
Terracciano, S.; Chini, M.G.; Riccio, R.; Bruno, I.; Bifulco, G.
Design, synthesis, and biological activity of hydroxamic tertiary amines as histone deacetylase inhibitors
ChemMedChem
7
694-702
2012
Homo sapiens, Aquifex aeolicus (O67135)
Icardi, L.; Lievens, S.; Mori, R.; Piessevaux, J.; De Cauwer, L.; De Bosscher, K.; Tavernier, J.
Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2
FASEB J.
26
240-249
2012
Homo sapiens
Smith, K.M.; Dobosy, J.R.; Reifsnyder, J.E.; Rountree, M.R.; Anderson, D.C.; Green, G.R.; Selker, E.U.
H2B- and H3-specific histone deacetylases are required for DNA methylation in Neurospora crassa
Genetics
186
1207-1216
2010
Neurospora crassa (Q7RY64), Neurospora crassa (Q7S8C9), Neurospora crassa (Q7SEB0), Neurospora crassa (Q7SEL7), Neurospora crassa
Muralidhar, S.A.; Ramakrishnan, V.; Kalra, I.S.; Li, W.; Pace, B.S.
Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells
J. Biol. Chem.
286
2343-2353
2011
Homo sapiens
Chen, Y.; Huang, P.; Ai, W.; Li, X.; Guo, W.; Zhang, J.; Yang, J.
Histone deacetylase activity is decreased in peripheral blood monocytes in patients with COPD
J. Inflamm.
9
10
2012
Homo sapiens
Mahboobi, S.; Sellmer, A.; Winkler, M.; Eichhorn, E.; Pongratz, H.; Ciossek, T.; Baer, T.; Maier, T.; Beckers, T.
Novel chimeric histone deacetylase inhibitors: a series of lapatinib hybrides as potent inhibitors of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and histone deacetylase activity
J. Med. Chem.
53
8546-8555
2010
Homo sapiens
Kaufmann, I.; White, E.; Azad, A.; Marguerat, S.; Baehler, J.; Proudfoot, N.J.
Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase
Mol. Cell. Biol.
30
3396-3410
2010
Schizosaccharomyces pombe
Hnilicova, J.; Hozeifi, S.; Duskova, E.; Icha, J.; Tomankova, T.; Stanek, D.
Histone deacetylase activity modulates alternative splicing
PLoS ONE
6
e16727
2011
Homo sapiens
Meyners, C.; Baud, M.G.; Fuchter, M.J.; Meyer-Almes, F.J.
Kinetic method for the large-scale analysis of the binding mechanism of histone deacetylase inhibitors
Anal. Biochem.
460
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2014
Homo sapiens (Q13547), Homo sapiens (Q9BY41), Homo sapiens (Q9UBN7), Homo sapiens, Alcaligenes sp. (Q70I53), Alcaligenes sp. DSM 11172 (Q70I53)
Karthikeyan, G.; Paul-Satyaseela, M.; Dhatchana Moorthy, N.; Gopalaswamy, R.; Narayanan, S.
Functional characterization of Candida albicans Hos2 histone deacetylase
F1000Res.
2
238
2013
Candida albicans, Candida albicans ATCC 90028
Huang, J.; Barr, E.; Rudnick, D.A.
Characterization of the regulation and function of zinc-dependent histone deacetylases during rodent liver regeneration
Hepatology
57
1742-1751
2013
Mus musculus
Wong, J.C.; Tang, G.; Wu, X.; Liang, C.; Zhang, Z.; Guo, L.; Peng, Z.; Zhang, W.; Lin, X.; Wang, Z.; Mei, J.; Chen, J.; Pan, S.; Zhang, N.; Liu, Y.; Zhou, M.; Feng, L.; Zhao, W.; Li, S.; Zhang, C.; Zhang, M.; Rong, Y.; Jin, T.G.; Zhang, X.; Ren, S.; Ji, Y.; Zhao, R.; She, J.; Ren, Y.; Xu, C.; Chen, D.; Cai, J.; Shan, S.
Pharmacokinetic optimization of class-selective histone deacetylase inhibitors and identification of associated candidate predictive biomarkers of hepatocellular carcinoma tumor response
J. Med. Chem.
55
8903-8925
2012
Homo sapiens (Q13547), Mus musculus (O09106), Mus musculus
Hnisz, D.; Bardet, A.F.; Nobile, C.J.; Petryshyn, A.; Glaser, W.; Schoeck, U.; Stark, A.; Kuchler, K.
A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis
PLoS Genet.
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e1003118
2012
Candida albicans
Ma, P.; Schultz, R.M.
Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse
PLoS Genet.
9
e1003377
2013
Mus musculus (P70288), Mus musculus
Kim, B.; Pithadia, A.S.; Fierke, C.A.
Kinetics and thermodynamics of metal-binding to histone deacetylase 8
Protein Sci.
24
354-365
2015
Homo sapiens (Q9BY41)
Munkhjargal, T.; Aboulaila, M.; Ueno, A.; Sivakumar, T.; Nakano, Y.; Yokoyama, M.; Yokoyama, N.; Igarashi, I.
Cloning and characterization of histone deacetylase from Babesia bovis
Vet. Parasitol.
190
423-433
2012
Babesia bovis
Kraemer, A.; Wagner, T.; Yildiz, O.e.; Meyer-Almes, F.J.
Crystal structure of a histone deacetylase homologue from Pseudomonas aeruginosa
Biochemistry
55
6858-6868
2016
Pseudomonas aeruginosa (Q9HXM1), Pseudomonas aeruginosa, Pseudomonas aeruginosa 1C (Q9HXM1), Pseudomonas aeruginosa ATCC 15692 (Q9HXM1), Pseudomonas aeruginosa CIP 104116 (Q9HXM1), Pseudomonas aeruginosa DSM 22644 (Q9HXM1), Pseudomonas aeruginosa JCM 14847 (Q9HXM1), Pseudomonas aeruginosa LMG 12228 (Q9HXM1), Pseudomonas aeruginosa PRS 101 (Q9HXM1)
Castaneda, C.A.; Lopez, J.E.; Joseph, C.G.; Scholle, M.D.; Mrksich, M.; Fierke, C.A.
Active site metal identity alters histone deacetylase 8 substrate selectivity a potential novel regulatory mechanism
Biochemistry
56
5663-5670
2017
Homo sapiens (Q9BY41)
Wagner, F.F.; Weiwer, M.; Steinbacher, S.; Schomburg, A.; Reinemer, P.; Gale, J.P.; Campbell, A.J.; Fisher, S.L.; Zhao, W.N.; Reis, S.A.; Hennig, K.M.; Thomas, M.; Mueller, P.; Jefson, M.R.; Fass, D.M.; Haggarty, S.J.; Zhang, Y.L.; Holson, E.B.
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors
Bioorg. Med. Chem.
24
4008-4015
2016
Homo sapiens (O15379), Homo sapiens (Q13547), Homo sapiens (Q92769)
Tomimoto, K.; Akao, T.; Fukuda, H.
Histone deacetylases in sake yeast affect fermentation characteristics
Biosci. Biotechnol. Biochem.
83
1498-1505
2019
Saccharomyces cerevisiae (P32561), Saccharomyces cerevisiae (P53973), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P32561), Saccharomyces cerevisiae ATCC 204508 (P53973)
Stefan, A.; Calonghi, N.; Schipani, F.; Dal Piaz, F.; Sartor, G.; Hochkoeppler, A.
Purification of active recombinant human histone deacetylase 1 (HDAC1) overexpressed in Escherichia coli
Biotechnol. Lett.
40
1355-1363
2018
Homo sapiens (Q13547), Homo sapiens
Yang, C.; Shen, W.; Chen, H.; Chu, L.; Xu, Y.; Zhou, X.; Liu, C.; Chen, C.; Zeng, J.; Liu, J.; Li, Q.; Gao, C.; Charron, J.B.; Luo, M.
Characterization and subcellular localization of histone deacetylases and their roles in response to abiotic stresses in soybean
BMC Plant Biol.
18
226
2018
Glycine max (A0A0R0FIH2), Glycine max (A0A0R0H2W2), Glycine max (A0A0R0JU82), Glycine max (A0A0R0K0I2), Glycine max (I1JB12), Glycine max (I1JZJ1), Glycine max (I1K037), Glycine max (I1LFN1), Glycine max (I1LKU7), Glycine max (I1LTZ2), Glycine max (I1LWR2), Glycine max (I1MTD8), Glycine max (I1MUF8), Glycine max (I1MXC3), Glycine max (K7K0Q1), Glycine max (K7KKZ9), Glycine max (K7KL00), Glycine max (K7KR69), Glycine max
Kasler, H.G.; Lee, I.S.; Lim, H.W.; Verdin, E.
Histone deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant natural killer T cells
eLife
7
e32109
2018
Mus musculus (Q8C2B3), Homo sapiens (Q8WUI4), Homo sapiens, Mus musculus C57BL/6 (Q8C2B3)
Yang, Z.; Shen, M.; Tang, M.; Zhang, W.; Cui, X.; Zhang, Z.; Pei, H.; Li, Y.; Hu, M.; Bai, P.; Chen, L.
Discovery of 1,2,4-oxadiazole-containing hydroxamic acid derivatives as histone deacetylase inhibitors potential application in cancer therapy
Eur. J. Med. Chem.
178
116-130
2019
Homo sapiens (Q13547), Homo sapiens (Q9UBN7), Homo sapiens
Kutil, Z.; Skultetyova, L.; Rauh, D.; Meleshin, M.; Snajdr, I.; Novakova, Z.; Mikesova, J.; Pavlicek, J.; Hadzima, M.; Baranova, P.; Havlinova, B.; Majer, P.; Schutkowski, M.; Barinka, C.
The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide libraries
FASEB J.
33
4035-4045
2019
Homo sapiens (Q9UBN7), Homo sapiens
Su, L.C.; Deng, B.; Liu, S.; Li, L.M.; Hu, B.; Zhong, Y.T.; Li, L.
Isolation and characterization of an osmotic stress and ABA induced histone deacetylase in Arachis hygogaea
Front. Plant Sci.
6
512
2015
Arachis hypogaea (A0A023IUM3), Arachis hypogaea
Buckwalter, J.M.; Chan, W.; Shuman, L.; Wildermuth, T.; Ellis-Mohl, J.; Walter, V.; Warrick, J.I.; Wu, X.R.; Kaag, M.; Raman, J.D.; DeGraff, D.J.
Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems
Int. J. Mol. Sci.
20
E2599
2019
Homo sapiens (P56524), Homo sapiens (Q8WUI4), Homo sapiens (Q9UKV0), Homo sapiens
Li, H.; Torres-Garcia, J.; Latrasse, D.; Benhamed, M.; Schilderink, S.; Zhou, W.; Kulikova, O.; Hirt, H.; Bisseling, T.
Plant-specific histone deacetylases HDT1/2 regulate GIBBERELLIN 2-OXIDASE2 expression to control Arabidopsis root meristem cell number
Plant Cell
29
2183-2196
2017
Arabidopsis thaliana (Q56WH4), Arabidopsis thaliana (Q9FVE6)
Shen, Y.; Lei, T.; Cui, X.; Liu, X.; Zhou, S.; Zheng, Y.; Guerard, F.; Issakidis-Bourguet, E.; Zhou, D.X.
Arabidopsis histone deacetylase HDA15 directly represses plant response to elevated ambient temperature
Plant J.
100
991-1006
2019
Arabidopsis thaliana (O22446), Arabidopsis thaliana (Q8GXJ1), Arabidopsis thaliana (Q8H0W2)
Ozawa, T.; Mizuhara, T.; Arata, M.; Shimada, M.; Niimi, T.; Okada, K.; Okada, Y.; Ohta, K.
Histone deacetylases control module-specific phenotypic plasticity in beetle weapons
Proc. Natl. Acad. Sci. USA
113
15042-15047
2016
Gnatocerus cornutus (A0A1L7N252), Gnatocerus cornutus (A0A1L7N254), Gnatocerus cornutus
Shen, H.; Zhu, Y.; Wang, C.; Yan, H.; Teng, M.; Li, X.
Structural and histone binding ability characterization of the ARB2 domain of a histone deacetylase Hda1 from Saccharomyces cerevisiae
Sci. Rep.
6
33905
2016
Saccharomyces cerevisiae (P53973), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P53973)
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