Any feedback?
Literature summary for 3.5.1.98 extracted from
- Purification and characterization of chicken erythrocyte histone deacetylase 1 (1999), Biochemistry, 38, 5939-5947.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | 10 mM, 66% inhibition | Gallus gallus |  |
| NaCl | inhibitory in sodium phosphate/citric acid buffer, 50% inhibition at 100 mM | Gallus gallus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 54938 | - |
1 * 66000, SDS-PAGE, 1 * 54938, calculated | Gallus gallus |
| 66000 | - |
1 * 66000, SDS-PAGE, 1 * 54938, calculated | Gallus gallus |
| 72000 | - |
gel filtration | Gallus gallus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | P56517 | isoform HDAC1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Gallus gallus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N6-lysine acetylated histone H2A-H2B dimer + H2O | - |
Gallus gallus | histone H3-H4 dimer + acetate | - |
? | |
| N6-lysine acetylated histone H3-H4 tetramer + H2O | preferred substrate | Gallus gallus | histone H3-H4 tetramer + acetate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 66000, SDS-PAGE, 1 * 54938, calculated | Gallus gallus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Gallus gallus |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Gallus gallus | calculated | - |
5.3 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
