Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.1.98 extracted from

  • Tomimoto, K.; Akao, T.; Fukuda, H.
    Histone deacetylases in sake yeast affect fermentation characteristics (2019), Biosci. Biotechnol. Biochem., 83, 1498-1505 .
    View publication on PubMed
Search for more literature for 3.5.1.98

Cloned(Commentary)

Cloned (Comment) Organism
gene hda1 Saccharomyces cerevisiae
gene rpd3 Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information establishment of HDAC RPD3 and accessory protein gene-disrupted strains, sake strain 701 with deleted gened encoding for other transcription regulatory proteins, e.g. RPD3, HDA1, SDS3, DEP1, and UME1, and NAD-dependent protein deacetylases, e.g. HST1, and quantitative real-time PCR of fusel alcohol or acetate ester synthesis related-genes in these strains, overview. Evaluation of sake fermenatation with the mutant strains, small-scale sake production test Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P32561 sake strain Kyokai No 701 and diverse deletion mutants
-
Saccharomyces cerevisiae P53973 sake strain Kyokai No 701 and diverse deletion mutants
-
Saccharomyces cerevisiae ATCC 204508 P32561 sake strain Kyokai No 701 and diverse deletion mutants
-
Saccharomyces cerevisiae ATCC 204508 P53973 sake strain Kyokai No 701 and diverse deletion mutants
-

Synonyms

Synonyms Comment Organism
hda1
-
 Saccharomyces cerevisiae
RPD3
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction K701 rpd3DELTA and K701 hda1DELTA alter the response to oxygen of isoamyl acetate production Saccharomyces cerevisiae
malfunction transcript levels of ILV2, ILV3 and ILV5 are elevated in Rpd3L-deficient strains (rpd3DELTA, ume1DELTA, dep1DELTA, and sds3DELTA) but not in Rpd3S-single deficient strain (rco1DELTA and eaf3DELTA) compared to wild-type K701. The transcript levels of ATF2, a minor alcohol acetyltransferase, are higher in the rpd3DELTA and ume1DELTA strains than in the parental strain. K701 rpd3DELTA and K701 hda1DELTA alter the response to oxygen of isoamyl acetate production Saccharomyces cerevisiae
additional information transcript analysis of genes responsible for the production of flavor components Saccharomyces cerevisiae
physiological function HDAC genes are non-essential in yeast, functional analysis of genes, RPD3, HDA1, SIR2, and HST1 in the Sake yeast strain Kyokai No. 701 (K701). RPD3 and Hda1 are translation regulatory proteins and histone deacetylases. Rpd3 and Hda1 may regulate isoamyl acetate production via oxygen in a Rox1-independent manner. Yeast HDACs, and maybe also HAT and their regulatory subunits, are keys to determine fermentation characteristics, and these genes may be an important target for improvement of yeast strains used for alcoholic beverage production Saccharomyces cerevisiae
physiological function HDAC genes are non-essential in yeast, functional analysis of genes, RPD3, HDA1, SIR2, and HST1 in the Sake yeast strain Kyokai No. 701 (K701). RPD3 and Hda1 are translation regulatory proteins and histone deacetylases. Rpd3L-dependent regulation of genes ILV2, ILV3 and ILV5. Rpd3 and Hda1 may regulate isoamyl acetate production via oxygen in a Rox1-independent manner. Yeast HDACs, and maybe also HAT and their regulatory subunits, are keys to determine fermentation characteristics, and these genes may be an important target for improvement of yeast strains used for alcoholic beverage production Saccharomyces cerevisiae