Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FOXP | FOXP3 specifically inhibits binding of histone deacetylase 2 and 4 to the site and increases local histone H3 acetylation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-lysine-histone H3 + H2O | - |
Homo sapiens | acetate + histone H3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HDAC2 | - |
Homo sapiens |
HDAC4 | - |
Homo sapiens |
histone deacetylase 2 | - |
Homo sapiens |
histone deacetylase 4 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | short hairpin-RNA silencing of either HDAC2 or HDAC4 is sufficient to induce p21 expression | Homo sapiens |