EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.1 | alcohol dehydrogenase |
lung |
- |
285604 |
1.1.1.1 | alcohol dehydrogenase |
lung |
isozyme ADH1 |
691867 |
1.1.1.10 | L-xylulose reductase |
lung |
- |
656049 |
1.1.1.10 | L-xylulose reductase |
lung |
high content |
656049 |
1.1.1.10 | L-xylulose reductase |
lung |
low expression level |
656049 |
1.1.1.101 | acylglycerone-phosphate reductase |
lung |
- |
285684 |
1.1.1.102 | 3-dehydrosphinganine reductase |
lung |
- |
285699 |
1.1.1.102 | 3-dehydrosphinganine reductase |
lung |
high expression |
656256 |
1.1.1.103 | L-threonine 3-dehydrogenase |
lung |
- |
655125 |
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
lung |
mRNA expression |
692959 |
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
lung |
significant amounts of RoDH-4 message is detected in fetal lung |
285727 |
1.1.1.112 | indanol dehydrogenase |
lung |
- |
285758 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
lung |
- |
285912, 285917, 285918, 285921, 285926, 348015, 667558, 668172, 668173, 669380, 670868, 685947, 697090 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
lung |
high enzyme expression level |
669380 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
lung |
of 28-days-old pregnant rabbits |
285921 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
lung |
- |
670264, 700178, 700441 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
lung |
adult and fetal, isozymes HSD1 and HSD2 |
667152 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
lung |
fetal, adult |
285958 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
lung |
- |
670111, 688031 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
lung |
moderate expression rate of AKR1C23 |
669908 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
lung |
- |
286024 |
1.1.1.184 | carbonyl reductase (NADPH) |
lung |
- |
347750, 347753, 347757, 347759, 347778, 670264, 697262, 697582 |
1.1.1.184 | carbonyl reductase (NADPH) |
lung |
ciliated cells, nonciliated bronchiolar cells, Type II alveolar pneumocytes, epithelial cells of the ducts of the bronchial gland |
347755 |
1.1.1.184 | carbonyl reductase (NADPH) |
lung |
low expression of CBR3 |
697582 |
1.1.1.188 | prostaglandin-F synthase |
lung |
- |
389444, 389448, 389449, 389453, 389458, 389464, 654740, 654851, 657211, 661605, 667713, 687797, 704349 |
1.1.1.188 | prostaglandin-F synthase |
lung |
contractile interstitial cells |
389451 |
1.1.1.188 | prostaglandin-F synthase |
lung |
low activity |
687797 |
1.1.1.188 | prostaglandin-F synthase |
lung |
low expression level |
760437 |
1.1.1.188 | prostaglandin-F synthase |
lung |
lung-type isozyme |
389454, 654159, 657211 |
1.1.1.188 | prostaglandin-F synthase |
lung |
PGFS-I, lung-type isozyme |
667422 |
1.1.1.188 | prostaglandin-F synthase |
lung |
PGH2 9-,11-endoperoxide reductase activity lung-type isozyme |
657211 |
1.1.1.188 | prostaglandin-F synthase |
lung |
two different active sites |
389452, 389455, 389456, 389460 |
1.1.1.189 | prostaglandin-E2 9-reductase |
lung |
- |
654851 |
1.1.1.197 | 15-hydroxyprostaglandin dehydrogenase (NADP+) |
lung |
- |
347830 |
1.1.1.2 | alcohol dehydrogenase (NADP+) |
lung |
- |
286182 |
1.1.1.21 | aldose reductase |
lung |
- |
286240, 667420, 697266, 738282 |
1.1.1.21 | aldose reductase |
lung |
highest enzyme activity is detected in the kidneys, followed by white adipose tissue and the lungs of prehibernating jerboa |
760913 |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
lung |
- |
741474 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
lung |
strong isoform AKR1C3 immunoreactivity in bronchial epithelium but not in bronchial glands or alveolar pneumocytes |
725153 |
1.1.1.225 | chlordecone reductase |
lung |
- |
286316 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
lung |
strong isoform AKR1C3 immunoreactivity in bronchial epithelium but not in bronchial glands or alveolar pneumocytes |
725153 |
1.1.1.27 | L-lactate dehydrogenase |
lung |
- |
740001 |
1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
lung |
- |
724124 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
lung |
- |
287891, 697214 |
1.1.1.300 | NADP-retinol dehydrogenase |
lung |
- |
654687, 761488 |
1.1.1.300 | NADP-retinol dehydrogenase |
lung |
high expression level |
686690 |
1.1.1.300 | NADP-retinol dehydrogenase |
lung |
low mRNA expression |
690876 |
1.1.1.300 | NADP-retinol dehydrogenase |
lung |
moderate level expression |
761488 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
lung |
10% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
lung |
a weak but detectable signal is present in normal lung, the 3 kb isoform is the most abundant one |
692332 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
lung |
expression of CRAD2 mRNA is 3% of that in liver |
692942 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
lung |
low activity |
692700 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
lung |
medium expression level |
722328 |
1.1.1.345 | D-2-hydroxyacid dehydrogenase (NAD+) |
lung |
- |
287843 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
lung |
- |
725333 |
1.1.1.41 | isocitrate dehydrogenase (NAD+) |
lung |
- |
741458 |
1.1.1.43 | phosphogluconate 2-dehydrogenase |
lung |
- |
688042 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
lung |
- |
286839 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
lung |
nicotine activates enzyme activity, increase in activity is eliminated by vitamin E |
688042 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
lung |
- |
675105 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
lung |
G6PD is more than 2fold higher in rat lungs than in rat hearts |
697523 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
lung |
- |
389547 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
lung |
in female hamsters |
740637 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
lung |
- |
688956, 762074 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
lung |
bronchial epithelial cells and walls of pulmonary arteries |
675190 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
lung |
bronchial epithelium |
287198 |
1.1.1.64 | testosterone 17beta-dehydrogenase (NADP+) |
lung |
strong isoform AKR1C3 immunoreactivity in bronchial epithelium but not in bronchial glands or alveolar pneumocytes |
725153 |
1.1.1.77 | lactaldehyde reductase |
lung |
- |
287308 |
1.1.1.78 | methylglyoxal reductase (NADH) |
lung |
- |
207968 |
1.1.1.96 | diiodophenylpyruvate reductase |
lung |
- |
287552 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
lung |
- |
700178 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
lung |
adult and fetal lung and cultured fetal lung explant contain similar amounts of isoform HSD2 mRNA. Higher levels of HSD2 protein are detected in fetal lung tissue than in adult lung, with expression being restricted to a subset of epithelial cells in the fetal lung tissue. Differentiated fetal lung explants express higher levels of enzyme protein than undifferentiated explants |
689337 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
lung |
adult and fetal, isozymes HSD1 and HSD2 |
667152 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
lung |
fetal, adult |
285958 |
1.1.99.24 | hydroxyacid-oxoacid transhydrogenase |
lung |
very low enzyme activity |
664967 |
1.10.5.1 | ribosyldihydronicotinamide dehydrogenase (quinone) |
lung |
- |
658430 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
lung |
- |
394867, 394871, 659398, 671327, 673845, 674370 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
lung |
parenchym |
688464 |
1.11.1.20 | prostamide/prostaglandin F2alpha synthase |
lung |
- |
687797 |
1.11.1.24 | thioredoxin-dependent peroxiredoxin |
lung |
0.001 mg Prx I per mg of soluble protein Prx I, 0.0013 mg Prx II per mg of soluble protein, 0.0003 mg Prx III per mg of soluble protein, 0.0003 mg Prx V per mg of soluble protein and 0.0017 mg Prx VI per mg of soluble protein |
655756 |
1.11.1.27 | glutathione-dependent peroxiredoxin |
lung |
- |
673786, 755233 |
1.11.1.27 | glutathione-dependent peroxiredoxin |
lung |
especially in type II alveolar epithelial cells and bronchiolar Clara cells |
710899 |
1.11.1.6 | catalase |
lung |
- |
439788 |
1.11.1.6 | catalase |
lung |
activity remains unaltered after exposure to 50 cGy whole body gamma-irradiation |
-, 674075 |
1.11.1.7 | peroxidase |
lung |
- |
698048 |
1.11.1.9 | glutathione peroxidase |
lung |
- |
396619, 396637, 688957 |
1.11.1.9 | glutathione peroxidase |
lung |
GPX1 |
675985 |
1.11.1.9 | glutathione peroxidase |
lung |
GPX3 |
675985 |
1.11.1.9 | glutathione peroxidase |
lung |
weak expression of pGPx |
672988 |
1.11.2.2 | myeloperoxidase |
lung |
- |
699699 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
lung |
- |
743358 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
lung |
endothelial cell expression in lung |
765516 |
1.13.11.19 | cysteamine dioxygenase |
lung |
- |
396418 |
1.13.11.20 | cysteine dioxygenase |
lung |
- |
657523, 742253 |
1.13.11.20 | cysteine dioxygenase |
lung |
alveolar epithelial cells, no enzyme detected in smooth muscle cells lining the alveoli or in blood vessels within the surrounding tissue |
659966 |
1.13.11.20 | cysteine dioxygenase |
lung |
easily detectable levels |
439556 |
1.13.11.20 | cysteine dioxygenase |
lung |
lower level than in liver |
657515 |
1.13.11.31 | arachidonate 12-lipoxygenase |
lung |
- |
395417, 395419, 763866, 765189 |
1.13.11.31 | arachidonate 12-lipoxygenase |
lung |
low activity |
395410 |
1.13.11.33 | arachidonate 15-lipoxygenase |
lung |
- |
639264, 674109 |