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Information on EC 1.11.1.9 - glutathione peroxidase

for references in articles please use BRENDA:EC1.11.1.9

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IUBMB Comments

A protein containing a selenocysteine residue. Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 lipoxygenase on phospholipids, can act as acceptor, but more slowly than H2O2 (cf. EC 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase).

The enzyme appears in viruses and cellular organisms

Synonyms
glutathione peroxidase, gpx, gsh-px, ebselen, gshpx, gpx-1, gsh peroxidase, glutathione peroxidase 1, plasma glutathione peroxidase, selenium-dependent glutathione peroxidase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 glutathione + H2O2 = glutathione disulfide + 2 H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
glutathione-peroxide redox reactions, reactive oxygen species degradation
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