Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

No. of entries

Information on EC 1.1.1.27 - L-lactate dehydrogenase

for references in articles please use BRENDA:EC1.1.1.27

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

Also oxidizes other (S)-2-hydroxymonocarboxylic acids. NADP+ also acts, more slowly, with the animal, but not the bacterial, enzyme.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes

Synonyms
lactate dehydrogenase, lactic dehydrogenase, ldh-a, lactate dehydrogenase a, l-lactate dehydrogenase, ldh-5, lactic acid dehydrogenase, ldh-1, pfldh, alpha-hydroxybutyrate dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-lactate + NAD+ = pyruvate + NADH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
(S)-lactate fermentation to propanoate, acetate and hydrogen, Bifidobacterium shunt, heterolactic fermentation, L-histidine degradation V, pyruvate fermentation to (S)-lactate, superpathway of glucose and xylose degradation