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Information on EC 1.1.1.211 - long-chain-3-hydroxyacyl-CoA dehydrogenase

for references in articles please use BRENDA:EC1.1.1.211
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IUBMB Comments
This enzyme was purified from the mitochondrial inner membrane. The enzyme has a preference for long-chain substrates, and activity with a C16 substrate was 6- to 15-fold higher than with a C4 substrate (cf. EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase).
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
lchad, long-chain 3-hydroxyacyl-coa dehydrogenase, mitochondrial trifunctional protein, beta-hydroxyacyl-coa dehydrogenase, hadha, long chain 3-hydroxyacyl-coa dehydrogenase, long-chain 3-hydroxyacyl coenzyme a dehydrogenase, long-chain 3-hydroxy-acyl-coa dehydrogenase, long-chain-(s)-3-hydroxyacyl-coa:nad+ oxidoreductase, long-chain l-3 hydroxyacyl-coa dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a long-chain (S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+
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