EC Number |
Recommended Name |
Application |
---|
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
diagnostics |
17beta-HSD1 is highly expressed in breast and ovary tissues and represents a prognostic marker for the tumor progression and survival of patients with breast cancer and other estrogen-dependent tumors |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
diagnostics |
2',3'-cyclic nucleotide 3'-phosphodiesterase is a stable marker for in situ detection of canine but not rat olfactory ensheathing cells |
2.4.1.17 | glucuronosyltransferase |
diagnostics |
3-epideacetycinobufagin can be used specially to measure the catalytic activity of UGT2B7 in biological samples due to its exclusive substrate specificty for the compound |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
diagnostics |
3-hydroxypalmitoleoyl-carnitine and other hydroxylated long chain acylcarnitines are markers of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) and/or trifunctional protein (TFP) deficiency, while heptadecanoylcarnitine is a biomarker specific for propionic acidemia (PA) or methylmalonic acidemia (MMA) patients able to detect propionate disorders during expanded newborn screening |
3.10.1.1 | N-sulfoglucosamine sulfohydrolase |
diagnostics |
a fluorimetric SGSH activity assay is commonly used to examine cells of mucopolysaccharidosis type IIIA patients for N-sulfoglucosamine sulfohydrolase activity, modification of the method for brain homogenates and definition of the parameters for assay linearity, overview |
1.1.3.4 | glucose oxidase |
diagnostics |
a glassy carbon electrode (GCE) is modified with carbon nanochips (CNCs), and glucose oxidase (GOx) is immobilized on the modified electrode surface. Chitosan (CS) is employed to fix the GOx/CNCs tightly to the surface of the GCE. Characterization of the modified electrode shows that glucose oxidase remains in its native structure when immobilized in CNC film. Application in glucose biosensing and biofuel cells |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
diagnostics |
a high HSD17B1 to HSD17B2 ratio, as well as high HSD17B1 on its own is associated with worse prognosis and increased risk of recurrence in patients with ERalpha-positive tumors. An increased copy number of the HSD17B1 gene is correlated with decreased breast cancer survival |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
diagnostics |
a high HSD17B1 to HSD17B2 ratio, as well as high HSD17B1 on its own is associated with worse prognosis and increased risk of recurrence in patients with ERalpha-positive tumors. An increased copy number of the HSD17B1 gene is correlated with decreased breast cancer survival |
1.14.19.30 | acyl-lipid (8-3)-desaturase |
diagnostics |
a higher serum concentration of the n-6 polyunsaturated fatty acid dihomo-gamma-linoleic acid and lower DELTA5-desaturase activity are associated with an increased risk of type 2 diabetes, independent of BMI, in Japanese adults |
1.1.2.3 | L-lactate dehydrogenase (cytochrome) |
diagnostics |
a mediatorless biosensor is developed that is based on flavocytochrome b2 immobilized onto gold nanoclusters for non-invasive L-lactate analysis of human liquids |
3.4.22.B49 | cathepsin L1 |
diagnostics |
a monoclonal antibody (MoAb) against recombinant Fasciola gigantica cathepsin L1H (rFgCatL1H) is produced by hybridoma technique using spleen cells from BALB/c mice immunized with recombinant proFgCatL1H (rproFgCatL1H). This MoAb is an immunoglobulin (Ig)G1 with kappa light chain isotype. The MoAb reacts specifically with rproFgCatL1H, the native FgCatL1H at a molecular weight (MW) 38-48 kDa in the extract of whole body (WB) of metacercariae and newly excysted juvenile (NEJ) and cross-reacted with rFgCatL1 and native FgCatLs at MW 25 to 28 kDa in WB of 2- and 4-week-old juveniles, adult, and adult excretory-secretory (ES) fractions by immunoblotting and indirect ELISA. It does not cross-react with antigens in WB fractions from other parasites. FgCatL1H and its MoAb may be used for immunodiagnosis of both early and late fasciolosis in ruminants and humans |
2.7.7.7 | DNA-directed DNA polymerase |
diagnostics |
a mutated thermostable DNA polymerase, Taq M1, from Thermus aquaticus, that exhibits an increased reverse transcriptase activity, is therefore designated for one-step PCR pathogen detection using established real-time detection methods |
1.5.3.1 | sarcosine oxidase (formaldehyde-forming) |
diagnostics |
a photobioelectrochemical sensor based on CdSe/ZnS quantum dot and sarcosine oxidase is developed to determine sarcosine concentrations. The linear range is from 0.1 mM to 1 mM and the sensitivity depends on the number of immobilised enzyme layers.It is demonstrated that the [SOD/PAH]6-layer system is well suited for sensitive sarcosine detection. Sarcosine is an intermediate in the enzymatic analysis of creatinine, and thus, a sarcosine sensor can be beneficial for the diagnosis of kidney diseases |
2.7.1.20 | adenosine kinase |
diagnostics |
a rapid and sensitive colorimetric assay for the determination of adenosine kinase activity is developed |
1.4.3.19 | glycine oxidase |
diagnostics |
a rapid and simple glycine analysis method is developed using a stable glycine oxidase mutant (T42 A/C245 S/L301V). Glycine analysis is important in research fields such as physiology and healthcare because the concentration of glycine in human plasma has been reported to change with various disorders |
3.2.1.18 | exo-alpha-sialidase |
diagnostics |
a rapid separation of human liver and bone alkaline phosphatase is possible after treatment with the enzyme |
1.4.3.22 | diamine oxidase |
diagnostics |
a research prototype ELISA is able to reliably and accurately quantify the human enzyme in different biological fluids. The potential of diamine oxidase as biomarker in various diseases can be evaluated |
3.4.22.56 | caspase-3 |
diagnostics |
a simple biochemical assay of caspase-3 activity in blood, may be useful for predicting the disposition of drugs that undergo extensive conjugation and biliary elimination like silymarin in patients with liver disease, caspase-3 activity correlates with the amount of silymarin conjugates, e.g. silychristin and silybin A and B, and is 5fold higher in the HCV cirrhosis cohort, overview |
4.1.1.17 | ornithine decarboxylase |
diagnostics |
a single nucleotide polymorphism in intron 1 of the ODC gene serves as genetic marker for colon cancer |
3.2.1.52 | beta-N-acetylhexosaminidase |
diagnostics |
a spectrophotometric method for the determination of lysosomally derived N-acetyl-beta-D-hexosaminidase in synovial fluid on a microplate reader is optimized to improve its utility. The assay is sufficiently sensitive for small volumes of synovial fluid, and is useful for the clinical diagnosis of joint diseases |
3.2.1.31 | beta-glucuronidase |
diagnostics |
a technique for MPS VII diagnosis is adapted for smaller amounts of sample and reagents. That will facilitate the use of smaller amounts of samples, which may be used for other techniques and to save material. Given the importance of early MPS VII diagnosis due to the severity of the disease, using reliable diagnostic techniques in dried blood spots is essential |
3.2.1.28 | alpha,alpha-trehalase |
diagnostics |
a trehalase-based biosensor platform offers a versatile and convenient method for point-of-care applications as it does not require sample preparation or handling and can be integrated with existing glucometers or sensors |
3.4.17.23 | angiotensin-converting enzyme 2 |
diagnostics |
ACE2 levels is a putative early biomarker of SARS-CoV-2 infection severity |
3.1.1.7 | acetylcholinesterase |
diagnostics |
AChE activity can be used as a biomarker of neurotoxic metal elements, such as lead, cadmium and copper |
1.14.11.2 | procollagen-proline 4-dioxygenase |
diagnostics |
activation of NF-kappaB is observed in colon cancer. PHD3 appears to be a tumor suppressor in colorectal cancer cells that inhibits IKKbeta/NF-kappaB signaling. Determination of PHD3 status could aid targeted therapy selection for patients with colorectal tumors that have increased NF-kappaB activity |
3.4.22.56 | caspase-3 |
diagnostics |
active caspase-3 immunostaining is considered as a highly reliable and specific morphological marker of early apoptosis |
4.2.1.1 | carbonic anhydrase |
diagnostics |
activity of carbonic anhydrase is significantly lower in patients with renal cell carcinoma than in controls. The marker carbonic anhydrase might be potentially important as an additional biochemical tool for diagnosing renal cell carcinoma |
3.4.24.87 | ADAMTS13 endopeptidase |
diagnostics |
ADAMTS-13 may serve as a diagnostic and prognostic marker of disseminated intravascular coagulation. Patients with a low activity of ADAMTS-13 have a poor survival rate compared to patients with a high activity of ADAMTS-13 |
3.5.4.4 | adenosine deaminase |
diagnostics |
adenosine deaminase activity in pleural effusions due to Legionnaires disease may be as high as that in pleural effusions due to tuberculosis. In countries where the prevalence of tuberculosis is high and pleural fluid adenosine deaminase activities are frequently measured, Legionnaires disease should be included in the differential diagnosis of an exudative pleural effusion with a high ADA activity |
3.5.4.4 | adenosine deaminase |
diagnostics |
adenosine deaminase activity is significantly higher in patients with renal cell carcinoma than in controls. The marker adenosine deaminase might be potentially important as an additional biochemical tool for diagnosing renal cell carcinoma |
3.5.4.4 | adenosine deaminase |
diagnostics |
adenosine deaminase analysis is a sensitive marker of tuberculous pleuritis even in HIV patients with very low CD4 counts in a high tuberculosis endemic region. The adenosine deaminase assay is inexpensive, rapid, and simple to perform and is of great value for the immediate diagnosis of tuberculous pleuritis while waiting for culture result and this has a positive impact on patient outcome |
3.5.4.4 | adenosine deaminase |
diagnostics |
adenosine deaminase is a very useful biochemical parameter in diagnostic analysis tuberculous pleural effusion. When combined with cytologic examination the results are even better |
3.5.4.4 | adenosine deaminase |
diagnostics |
adenosine deaminase may be used as a supportive marker to differentiate familial mediterranean fever attacks from attack-free periods |
2.7.4.3 | adenylate kinase |
diagnostics |
adenylate kinase-specific IFN-gamma production and B-cell responses have high potential for diagnosis of tuberculosis |
1.1.99.24 | hydroxyacid-oxoacid transhydrogenase |
diagnostics |
AHDFE1 mRNA expression and DNA methylation can potentially be used as diagnostic markers in cancer and might be of great value in predicting the survival of patients with cancer. High expression of ADHFE1 is positively associated with favorable patient prognosis in breast, colon, and gastric cancers |
1.1.1.21 | aldose reductase |
diagnostics |
AKR1B10 may have a potential role as a tumor marker |
1.2.1.36 | retinal dehydrogenase |
diagnostics |
ALDH1A1 is rapidly gaining importance as a stem cell marker |
3.2.1.51 | alpha-L-fucosidase |
diagnostics |
alpha-L-fucosidase is a valuable diagnostic biomarker for hepatocellular carcinoma. An ultrasensitive plasmonic biosensor converts plasmonic absorption to electrical current in order to detect alpha-L-fucosidase and cardiac troponin I using whole human blood in a real-time and parallel fashion. The detection limit is calculated to be 0.016 U/L for alpha-L-fucosidase and 0.015 ng/mL for cardiac troponin I, respectively. The developed biosensor exhibits a promising application for the prediction of cancers and many other diseases |
3.4.21.68 | t-Plasminogen activator |
diagnostics |
alterations in tPA activity levels can be used as a biomarker for perturbations in brain homeostasis |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
diagnostics |
altered ARSB immunostaining and reduced activity may be useful indicators of malignant transformation in human colonic tissue |
5.1.99.4 | alpha-methylacyl-CoA racemase |
diagnostics |
AMACR is established as a valuable diagnostic marker for prostate cancer and has shown to be useful in the diagnosis of colorectal carcinoma |
3.4.11.2 | membrane alanyl aminopeptidase |
diagnostics |
aminopeptidase N is a diagnostic marker for hepatocellular carcinoma using canalicular immunostaining |
2.7.4.33 | AMP-polyphosphate phosphotransferase |
diagnostics |
AMP is known to have potential for use as a reliable indicator in hygiene monitoring, the development of a sensitive method for detecting AMP, by using polyphosphate-AMP phosphotransferase and adenylate kinase in conjugation with firefly luciferase, is useful to detect food samples with high sensitivity |
3.2.1.46 | galactosylceramidase |
diagnostics |
an assay is developed that can measure small amounts of residual galactosylcerebrosidase activity in leukocytes with high accuracy and can contribute, along with genotyping, biomarker analysis, and neurological imaging, a better plan for post-newborn screening follow-up for Krabbe disease |
1.1.3.2 | L-lactate oxidase |
diagnostics |
an improved amperometric L-lactate biosensor was constructed based on covalent immobilization of lactate oxidase from Pediococcus species onto carboxylated multiwalled carbon nanotubes (cMWCNT)/copper nanoparticles (CuNPs)/polyaniline (PANI) hybrid film electrodeposited on the surface of a pencil graphite electrode. The biosensor shows maximum response within 5 s at pH 8.0 in 0.05 M sodium phosphate buffer and 37°C, when operated at 20 mV/s. The biosensor has a detection limit of 0.00025 mM with a wide working range between 0.001-2.5 mM. The biosensor is employed for measurement of L-lactic acid level in plasma of apparently healthy and diseased persons. Analytical recovery of added lactic acid in plasma is 95.5%. The working enzyme electrode is used 180 times over a period of 140 days, when stored at 4°C |
3.4.22.27 | cathepsin S |
diagnostics |
an increased serum level of cathepsin S may serve as a biomarker for atherosclerosis and diabetes |
1.1.3.2 | L-lactate oxidase |
diagnostics |
an integrated tear lactate sensor using Schirmer test strip and engineered lactate oxidase is developed. The sensor is insensitive to ascorbic acid, acetaminophen, and uric acid, which are common interfering compounds in tears, and show no sign of degradation after 8 weeks of shelf life study. The proposed sensor exhibits potential usefulness in providing an alternative noninvasive method of measuring lactate and in calibrating the continuous lactate contact lens |
1.1.5.9 | glucose 1-dehydrogenase (FAD, quinone) |
diagnostics |
an oxygen insensitive glucose biosensor is developed which comprises FAD-dependent glucose dehydrogenase, dichlorophenol indophenol or 2,3-dichloro-naphthoquinone as redox mediators and polydopamine as a constraining layer. It shows long term bioelectrocatalytic activity for at least 3 days without any additional coating or treatment. The system shows great reproducibility, as well as an easy fabrication methodology that should allow low-cost manufacturing |
3.5.4.4 | adenosine deaminase |
diagnostics |
analysis of adenosine deaminase in saliva could be used as a simple, rapid, economic and non-invasive diagnostic tool in porcine production in field conditions |
2.4.1.109 | dolichyl-phosphate-mannose-protein mannosyltransferase |
diagnostics |
analysis of fibroblasts to elucidate the phenotypes of POMT1 mutations |
2.7.10.1 | receptor protein-tyrosine kinase |
diagnostics |
analysis of in situ ERBB signaling networks in conjunction with ex vivo drug response profiling and biochemical dissection of adaptive RTK activities may serve as a valid diagnostic approach to identify tumors sensitive to ERBB network inhibition |
3.4.22.B60 | cathepsin L2 |
diagnostics |
analysis of the diagnostic values of the three different clades of cathepsin Ls, FhCL1, FhCL2, and FhCL5, from adult flukes in an ELISA, test of sera from sheep and cattle naturally infected with Fasciola hepatica, assessment of cross-reactive antibodies, overview. For sheep sera, the sensitivity is 100% for the three rFhpCLs, while for cattle sera, the highest sensitivity is obtained using rFhpCL2 (97%), being equal for both rFhpCL1 and rFhpCL5 (87.9%), after adjusting cut-offs for maximum specificity |
3.4.22.B49 | cathepsin L1 |
diagnostics |
analysis of the diagnostic values of the three different clades of cathepsin Ls, FhCL1, FhCL2, and FhCL5, from adult flukes in an ELISA, test of sera from sheep and cattle naturally infected with Fasciola hepatica, of cross-reactive antibodies, overview. For sheep sera, the sensitivity is 100% for the three rFhpCLs, while for cattle sera, the highest sensitivity is obtained using rFhpCL2 (97%), being equal for both rFhpCL1 and rFhpCL5 (87.9%), after adjusting cut-offs for maximum specificity |
3.4.22.B61 | cathepsin L5 |
diagnostics |
analysis of the diagnostic values of the three different clades of cathepsin Ls, FhCL1, FhCL2, and FhCL5, from adult flukes in an ELISA, test of sera from sheep and cattle naturally infected with Fasciola hepatica, of cross-reactive antibodies, overview. For sheep sera, the sensitivity is 100% for the three rFhpCLs, while for cattle sera, the highest sensitivity is obtained using rFhpCL2 (97%), being equal for both rFhpCL1 and rFhpCL5 (87.9%), after adjusting cut-offs for maximum specificity |
1.1.3.6 | cholesterol oxidase |
diagnostics |
analytic tool for determining cholesterol in various samples |
2.4.1.17 | glucuronosyltransferase |
diagnostics |
androgen glucuronidation by UGT2B17 is particularly interesting in doping control |
3.4.21.76 | Myeloblastin |
diagnostics |
anti-neutrophil cytoplasmic antibodies with proteinase 3 specificity are a useful laboratory biomarker for the diagnosis of granulomatosis with polyangiitis, i.e.Wegener's granulomatosis |
1.3.1.24 | biliverdin reductase |
diagnostics |
antiapoptotic effect of the enzyme in cancers portens strategies for developing novel biomarkers and effective treatment ways for cancer patients |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
diagnostics |
APE1/Ref-1 expression levels together with subcellular dysregulation may be predictive markers to indicate the tumor sensitivity toward radiotherapy or chemotherapy |
3.1.1.7 | acetylcholinesterase |
diagnostics |
application in AChE biosensor |
1.14.11.18 | phytanoyl-CoA dioxygenase |
diagnostics |
assays for Refsums disease should not be based on PAHX activity alone. At least four different types of mutation cause loss of PAHX activity in vivo. Mutations to the peroxisomal targeting sequence do not affect catalytic function but probably affect targeting or degradation of the enzyme. A second group of mutations, including truncation and missense mutations, results in total loss of activity. A third group of mutations results in uncoupling of substrate oxidation from that of 2-oxoglutarate. A fourth group of mutations causes partial inactivation by hindering binding/utilization of the 2-oxoglutarate cosubstrate and/or iron(II) cofactor. From the therapeutic and biochemical view-point the latter two groups are particularly interesting since it may be possible to restore their activity with modified cosubstrates |
2.7.1.158 | inositol-pentakisphosphate 2-kinase |
diagnostics |
assessing early kidney structural damage in diabetic kidney disease (DKD) via a urine biomarker is an appealing goal, and IPP2K may be a promising candidate |
3.4.24.24 | gelatinase A |
diagnostics |
assessment of enzyme for monitoring and screening patients with prostate cancer. Significant correlation of densitometric analysis of enzyme activity and indirect hemagglutination titer, and prostate-specific antigen parameters |
3.1.1.56 | methylumbelliferyl-acetate deacetylase |
diagnostics |
assisting early retinoblastoma diagnosis |
3.4.24.23 | matrilysin |
diagnostics |
associated expression of metalloproteinase-1, metalloproteinase-7 and VEGF in colorectal adenocarcinoma is related to the incidence of disease recurrence |
3.4.24.B3 | matrix metalloproteinase-11 |
diagnostics |
association between the clinicopathological characteristics and MMP-11 expression in oral squamous cell carcinoma (OSCC) patients, expression of MMP-11 is associated with higher incidence of lymph node metastasis and worse grade of tumor differentiation, overview. The MMP-11 expression in OSCC samples can predict the progression, especially lymph node metastasis, and the survival of OSCC patients in Taiwan |
1.8.1.4 | dihydrolipoyl dehydrogenase |
diagnostics |
Bacillus sphaericus DLD-diaphorase exhibits considerable potential to be used as a component of diagnostic tests for the quantification of metabolites |
3.2.1.31 | beta-glucuronidase |
diagnostics |
beta-glucuronidase activity is a sensitive biomarker to assess low-level organophosphorus insecticide exposure, e.g. plasma BG activity for low-level organophosphorus-exposure compared to BChE activity, overview |
1.1.2.B5 | PQQ-dependent quinohemoprotein pyranose dehydrogenase |
diagnostics |
bioelectrochemical applications (an amperometric biosensor) in electrochemical devices, based on direct electron transfer reactions. Development of a biosensor to detect urinary L-fucose |
5.1.99.4 | alpha-methylacyl-CoA racemase |
diagnostics |
biomarker for cancer in prostate, breast, colon, renal and other cancer cells |
1.1.99.35 | soluble quinoprotein glucose dehydrogenase |
diagnostics |
biosensor |
3.1.3.1 | alkaline phosphatase |
diagnostics |
biosensors |
6.3.4.15 | biotin-[biotin carboxyl-carrier protein] ligase |
diagnostics |
BirA can be useful for specific in vivo labeling of proteins in cell cultures by biotinylation |
1.3.3.5 | bilirubin oxidase |
diagnostics |
BOD is used for diagnostic analysis of bilirubin in serum |
5.1.1.10 | amino-acid racemase |
diagnostics |
broad-specificity amino acid racemase is a non-antibiotic selectable marker for transgenic plants and can be used in the development of genetically modified plants without using antibiotic resistance marker genes. Selection with different amino acid enantiomers using Bsar, Bsar-R174A and Bsar-R174K gene as selectable markers, overview |
3.5.1.12 | biotinidase |
diagnostics |
BTD is a biomarker for the hepatic glycogen storage disease, overview |
3.5.1.12 | biotinidase |
diagnostics |
BTD is a potential serological biomarker for the detection of breast cancer to use with plasma |
3.1.1.8 | cholinesterase |
diagnostics |
BuChE is a possible marker for Alzheimer's disease |
3.1.1.8 | cholinesterase |
diagnostics |
butyrylcholinesterase activity is a sensitive and specific biomarker of Alzheimers disease (AD), BChE-associated amyloid-beta plaques has the potential as an improved AD biomarker. The predictive value of BChE as a biomarker for AD facilitates timely disease diagnosis and management |
2.4.1.122 | N-acetylgalactosaminide beta-1,3-galactosyltransferase |
diagnostics |
C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
diagnostics |
C2GnT1 might become a prognostic factor for endometrial carcinoma. Patients with C2GnT1 overexpression show significantly shorter survival, multivariable analysis also indicate that 2GnT1 overexpression is an independent prognostic factor |
3.4.17.10 | carboxypeptidase E |
diagnostics |
carboxypeptidase E is a prediction marker for tumor recurrence in early-stage hepatocellular carcinoma |
3.4.22.56 | caspase-3 |
diagnostics |
caspase-3 activity is a marker for apoptosis in gut epithelium, leading to impairment of the gastrointestinal mucosal barrier, that contributes to progression of HIV infection, immunohistochemical staining of cleaved caspase-3, overview |
3.4.22.56 | caspase-3 |
diagnostics |
caspase-3 activity is a marker for cell death, e.g. in microglia, overview |
3.4.22.56 | caspase-3 |
diagnostics |
caspase-3 can act as apoptosis marker |
3.4.22.56 | caspase-3 |
diagnostics |
caspase-3 is a helpful indicator of apoptosis induction, e.g. in mammary carcinomas |
3.4.22.56 | caspase-3 |
diagnostics |
caspase-3 is a marker for apoptosis, e.g. useful in patients with urothelial carcinoma of the upper urinary tract, overview |
3.4.22.56 | caspase-3 |
diagnostics |
caspase-3 is a marker of apoptotic cell death in embryonic fibroblasts, NIH-3T3 and WST-1 cells |
1.11.1.6 | catalase |
diagnostics |
catalase activity is significantly higher in patients with renal cell carcinoma than in controls. The marker catalase might be potentially important as an additional biochemical tool for diagnosing renal cell carcinoma |
3.4.22.1 | cathepsin B |
diagnostics |
CATB is a potent and independent prognostic marker for resectable pancreatic adenocarcinoma |
3.4.22.1 | cathepsin B |
diagnostics |
cathepsin B activity can be a useful marker of oocyte quality |
3.4.22.1 | cathepsin B |
diagnostics |
cathepsin B is a biologic marker reflecting the clinical state of inflammatory disease |
3.4.22.1 | cathepsin B |
diagnostics |
cathepsin B is a possible prognostic biomarker for the aggressiveness of ovarian cancer, overview |
3.4.22.1 | cathepsin B |
diagnostics |
cathepsin B is an important biomarker for the stratification of glioblastoma patients with respect to survival |
3.4.22.27 | cathepsin S |
diagnostics |
cathepsin S is a biomarker for adiposity and has relevance to atherogenesis |
3.4.18.1 | cathepsin X |
diagnostics |
Cathepsin X is an inflammatory marker |
2.7.7.15 | choline-phosphate cytidylyltransferase |
diagnostics |
CCT-alpha status is not predictive of outcome of neoadjuvant cisplatin-based chemotherapy response in patients with T2-T4 bladder cancer. In the control group with cystectomy only it has prognostic value |
3.1.21.1 | deoxyribonuclease I |
diagnostics |
cell-free DNA circulating in blood cannot be a reliable marker of increased cell death during pregnancy. Thus, assessment of the level of cell death during pregnancy should be done by simultaneous analysis of cell-free DNA level and DNase I activity |
1.1.1.80 | isopropanol dehydrogenase (NADP+) |
diagnostics |
characterization of adrenal and gonadal tissue |
2.3.1.6 | choline O-acetyltransferase |
diagnostics |
ChAT is selected as a marker of cholinergicneurons. In the CA1 region of hippocampus of mice, several of the insulin signaling-related proteins are co-located with ChAT, and most double immunoreactive positive cells are pyramidal cells |