Information on EC 3.4.24.24 - gelatinase A

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY
3.4.24.24
-
RECOMMENDED NAME
GeneOntology No.
gelatinase A
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-/-Ile-Ala-Gly-Gln
show the reaction diagram
cleaves the collagen-like sequence Pro-Gln-Gly-+-Ile-Ala-Gly-Gln, the term -+- depicts the point of cleavage
-
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of peptide bond
-
-
-
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
72 kDa Gelatinase
-
-
-
-
72 kDa Gelatinase type A
-
-
-
-
72 kDa type IV collagenase
-
-
72-kDa Gelatinase
-
-
-
-
72-kDa Gelatinase
-
-
Collagenase IV
-
-
-
-
Collagenase type IV
-
-
-
-
gelatinase A
-
-
human gelatinase A
-
-
human matrix metalloproteinase 2
-
-
human matrix metalloproteinase-2
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-
matrix metalloprotease 2
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-
Matrix metalloproteinase 2
-
-
-
-
Matrix metalloproteinase 2
-
-
matrix metalloproteinase-2
-
-
matrix metalloproteinase-2
P08253
-
matrix metalloproteinase-2
-
-
matrix metalloproteinase-2
-
-
matrix metalloprotenase-2
-
-
metalloproteinase-2
-
-
metrix metalloproteinase-2
-
-
MMP 2
-
-
-
-
MMP-2
-
-
MMP-2
P08253
-
MMP-2
-
-
MMP-2
Rattus norvegicus Wistar
-
-
-
MMP-2
-
-
MMP2
-
-
Type IV collagen metalloproteinase
-
-
-
-
Type IV collagenase
-
-
-
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Type IV collagenase
-
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Type IV collagenase/gelatinase
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-
-
-
CAS REGISTRY NUMBER
COMMENTARY
146480-35-5
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
expression in Escherichia coli
-
-
Manually annotated by BRENDA team
MMP-2 is a constitutive enzyme
-
-
Manually annotated by BRENDA team
patients with benign prostate hyperplasia or prostate cancer
-
-
Manually annotated by BRENDA team
patients with bladder cancer
-
-
Manually annotated by BRENDA team
patients with degenerative disc disease
-
-
Manually annotated by BRENDA team
patients with oral squamous cell carcinomas
-
-
Manually annotated by BRENDA team
patients with pleural effusions, such as malignant pleural effusion, breast carcinoma or lung carcinoma
-
-
Manually annotated by BRENDA team
recombinant enzyme
-
-
Manually annotated by BRENDA team
recombinant enzyme expressed in a Vaccinia virus-mammalian cell expression system
-
-
Manually annotated by BRENDA team
recombinant enzyme expressed in NSO mouse myeloma cells
-
-
Manually annotated by BRENDA team
recombinant wild-type from a myeloma cell expression system
-
-
Manually annotated by BRENDA team
synthetic gene in which two polypeptide fragments of the catalytic domain are joined with the deletion of the 19000 MW fibronectin-like insert of the catalytic domain, expressed in Escherichia coli
-
-
Manually annotated by BRENDA team
Fisher344 rats
-
-
Manually annotated by BRENDA team
Sprague-Dawley rats
-
-
Manually annotated by BRENDA team
Rattus norvegicus Wistar
male
-
-
Manually annotated by BRENDA team
newborn undergoing hypoxia and reoxygenation
-
-
Manually annotated by BRENDA team